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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107003422.

Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function

Horacio Maldonado, Bryan D. Savage, Harlan R. Barker, Ulrike May, Maria Vähätupa, Rahul K. Badiani, Katarzyna I. Wolanska, Craig M. J. Turner, Toini Pemmari, Tuomo Ketomäki, Stuart Prince, Martin J. Humphries, Erkki Ruoslahti, Mark R. Morgan, Tero A. H. Järvinen

Nat Commun. 2023; 14: 8069. Published online 2023 Dec 6. doi: 10.1038/s41467-023-43848-1

Correction in:: Nat Commun. 2024; 15: 234.

PMCID:: PMC10700342

Abstract Article PDF–8.9M

Select item 102165873.

Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis

Tayler F. L. Wishart, Frank J. Lovicu

Cells. 2023 May; 12(10): 1364. Published online 2023 May 11. doi: 10.3390/cells12101364

PMCID:: PMC10216587

Abstract Article PDF–20M

Select item 101387974.

Unravelling the Effects of Syndecan-4 Knockdown on Skeletal Muscle Functions

Mónika Sztretye, Zoltán Singlár, Nyamkhuu Ganbat, Dána Al-Gaadi, Kitti Szabó, Zoltán Márton Köhler, László Dux, Anikó Keller-Pintér, László Csernoch, Péter Szentesi

Int J Mol Sci. 2023 Apr; 24(8): 6933. Published online 2023 Apr 8. doi: 10.3390/ijms24086933

PMCID:: PMC10138797

Abstract Article PDF–4.7M

Select item 101087065.

A distinct transcriptome characterizes neural crest-derived cells at the migratory wavefront during enteric nervous system development

Rhian Stavely, Ryo Hotta, Richard A. Guyer, Nicole Picard, Ahmed A. Rahman, Meredith Omer, Adam Soos, Emoke Szocs, Jessica Mueller, Allan M. Goldstein, Nandor Nagy

Development. 2023 Mar 1; 150(5): dev201090. Published online 2023 Mar 6. doi: 10.1242/dev.201090

PMCID:: PMC10108706

Abstract Article

Select item 97124076.

Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy

Ida G. Lunde, J. Magnus Aronsen, A. Olav Melleby, Mari E. Strand, Jonas Skogestad, Bård A. Bendiksen, M. Shakil Ahmed, Ivar Sjaastad, Håvard Attramadal, Cathrine R. Carlson, Geir Christensen

Mol Biol Rep. 2022; 49(12): 11795–11809. Published online 2022 Oct 7. doi: 10.1007/s11033-022-07985-y

PMCID:: PMC9712407

Abstract Article PDF–2.2M

Select item 96817397.

Cholesterol-induced LRP3 downregulation promotes cartilage degeneration in osteoarthritis by targeting Syndecan-4

Chenxi Cao, Yuanyuan Shi, Xin Zhang, Qi Li, Jiahao Zhang, Fengyuan Zhao, Qingyang Meng, Wenli Dai, Zhenlong Liu, Wenqiang Yan, Xiaoning Duan, Jiying Zhang, Xin Fu, Jin Cheng, Xiaoqing Hu, Yingfang Ao

Nat Commun. 2022; 13: 7139. Published online 2022 Nov 21. doi: 10.1038/s41467-022-34830-4

PMCID:: PMC9681739

Abstract Article PDF–5.2M

Select item 94528468.

The female syndecan-4^−/− heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels

Thea Parsberg Støle, Marianne Lunde, Xin Shen, Marita Martinsen, Per Kristian Lunde, Jia Li, Francesca Lockwood, Ivar Sjaastad, William Edward Louch, Jan Magnus Aronsen, Geir Christensen, Cathrine Rein Carlson

Front Cell Dev Biol. 2022; 10: 908126. Published online 2022 Aug 25. doi: 10.3389/fcell.2022.908126

PMCID:: PMC9452846

Abstract Article PDF–2.6M

Select item 93164279.

Biodistribution and Cellular Internalization of Inactivated SARS-CoV-2 in Wild-Type Mice

Anett Hudák, Gareth Morgan, Jaromir Bacovsky, Roland Patai, Tamás F. Polgár, Annamária Letoha, Aladar Pettko-Szandtner, Csaba Vizler, László Szilák, Tamás Letoha

Int J Mol Sci. 2022 Jul; 23(14): 7609. Published online 2022 Jul 9. doi: 10.3390/ijms23147609

PMCID:: PMC9316427

Abstract Article PDF–4.8M

Select item 928798610.

A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinflammatory capacity of macrophages

Jiaxin Hu, Ying Zhang, Liaoping Hu, Haiting Chen, Han Wu, Jianzhou Chen, Jun Xie, Biao Xu, Zhonghai Wei

J Transl Med. 2022; 20: 319. Published online 2022 Jul 16. doi: 10.1186/s12967-022-03505-5

PMCID:: PMC9287986

Abstract Article PDF–13M

Select item 903432011.

Proteomic analysis reveals exercise training induced remodelling of hepatokine secretion and uncovers syndecan-4 as a regulator of hepatic lipid metabolism

William De Nardo, Paula M. Miotto, Jacqueline Bayliss, Shuai Nie, Stacey N. Keenan, Magdalene K. Montgomery, Matthew J. Watt

Mol Metab. 2022 Jun; 60: 101491. Published online 2022 Apr 2. doi: 10.1016/j.molmet.2022.101491

PMCID:: PMC9034320

Abstract Article PDF–5.1M

Select item 881864212.

Syndecan-4 affects myogenesis via Rac1-mediated actin remodeling and exhibits copy-number amplification and increased expression in human rhabdomyosarcoma tumors

Kitti Szabo, Daniel Varga, Attila Gergely Vegh, Ning Liu, Xue Xiao, Lin Xu, Laszlo Dux, Miklos Erdelyi, Laszlo Rovo, Aniko Keller-Pinter

Cell Mol Life Sci. 2022 Feb; 79(2): 122. Published online 2022 Feb 7. doi: 10.1007/s00018-021-04121-0

PMCID:: PMC8818642

Abstract Article PDF–12M

Select item 831323913.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 829214514.

Inhibition of syndecan-4 reduces cartilage degradation in murine models of osteoarthritis through the downregulation of HIF-2α by miR-96-5p

Kai Zhou, Sirong He, Haoda Yu, Fuxing Pei, Zongke Zhou

Lab Invest. 2021; 101(8): 1060–1070. Published online 2021 Apr 13. doi: 10.1038/s41374-021-00595-5

PMCID:: PMC8292145

Abstract Article PDF–3.6M

Select item 793877015.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 761369916.

Pathological angiogenesis requires Syndecan-4 for efficient VEGFA-induced VE-Cadherin internalization

Giulia De Rossi, Maria Vähätupa, Enrico Cristante, Samantha Arokiasamy, Sidath E. Liyanage, Ulrike May, Laura Pellinen, Hannele Uusitalo-Järvinen, James W. Bainbridge, Tero A.H. Järvinen, James R. Whiteford

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Oct 13.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Apr 1; 41(4): 1374–1389. Published online 2021 Feb 18. doi: 10.1161/ATVBAHA.121.315941

PMCID:: PMC7613699

Abstract Article PDF–3.3M

Select item 743318517.

Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells

Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest, Lisette Leyton

Cell Commun Signal. 2020; 18: 129. Published online 2020 Aug 18. doi: 10.1186/s12964-020-00629-3

PMCID:: PMC7433185

Abstract Article PDF–2.8M

Select item 741599118.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 741100819.

Syndecan-4^–/– Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components

Sissel Beate Rønning, Cathrine Rein Carlson, Jan Magnus Aronsen, Addolorata Pisconti, Vibeke Høst, Marianne Lunde, Kristian Hovde Liland, Ivar Sjaastad, Svein Olav Kolset, Geir Christensen, Mona Elisabeth Pedersen

Front Cell Dev Biol. 2020; 8: 730. Published online 2020 Jul 31. doi: 10.3389/fcell.2020.00730

PMCID:: PMC7411008

Abstract Article PDF–3.8M

Select item 729392420.

The Spatiotemporal Expression Pattern of Syndecans in Murine Embryonic Teeth

Jingyi Wu, Hong Li, Lu Han, Tianyu Sun, Ye Tian, Xiaofang Wang

Gene Expr Patterns. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Gene Expr Patterns. 2020 Jun; 36: 119109. Published online 2020 Mar 24. doi: 10.1016/j.gep.2020.119109

PMCID:: PMC7293924

Abstract Article PDF–1.2M

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