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Select item 115417331.

ERα status of invasive ductal breast carcinoma as a result of regulatory interactions between lysine deacetylases KAT6A and KAT6B

Mateusz Olbromski, Monika Mrozowska, Beata Smolarz, Hanna Romanowicz, Agnieszka Rusak, Aleksandra Piotrowska

Sci Rep. 2024; 14: 26935. Published online 2024 Nov 6. doi: 10.1038/s41598-024-78432-0

PMCID:: PMC11541733

Abstract Article PDF–2.5M

Select item 114259132.

KAT6A Condensates Impair PARP1 Trapping of PARP Inhibitors in Ovarian Cancer

Zhiyan Zhan, Jiarong Zhang, Huisheng Liang, Chong Wang, Li Hong, Wenxue Liu

Adv Sci (Weinh) 2024 Sep; 11(34): 2400140. Published online 2024 Jul 8. doi: 10.1002/advs.202400140

PMCID:: PMC11425913

Abstract Article PDF–9.9M

Select item 113174543.

KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement

Kuang Tan, Jiayi Wang, Xinyu Su, Yunfei Zheng, Weiran Li

Prog Orthod. 2024; 25: 29. Published online 2024 Aug 12. doi: 10.1186/s40510-024-00530-6

PMCID:: PMC11317454

Abstract Article PDF–8.2M

Select item 112969144.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 111584765.

Roles of the histone acetyltransferase monocytic leukemia zinc finger protein in normal and malignant hematopoiesis

Takuo Katsumoto, Naomi Yoshida, Issay Kitabayashi

Cancer Sci. 2008 Aug; 99(8): 1523–1527. Published online 2008 Aug 14. doi: 10.1111/j.1349-7006.2008.00865.x

PMCID:: PMC11158476

Abstract Article PDF–244K

Select item 106763146.

KAT6A mutations in Arboleda-Tham syndrome drive epigenetic regulation of posterior HOXC cluster

Meghna Singh, Sarah J. Spendlove, Angela Wei, Leroy M. Bondhus, Aileen A. Nava, Francisca N. de L. Vitorino, Seth Amano, Jacob Lee, Gesenia Echeverria, Dianne Gomez, Benjamin A. Garcia, Valerie A. Arboleda

Hum Genet. 2023; 142(12): 1705–1720. Published online 2023 Oct 20. doi: 10.1007/s00439-023-02608-3

PMCID:: PMC10676314

Abstract Article PDF–4.2M

Select item 104607327.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 99088898.

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain

Dustin C. Becht, Brianna J. Klein, Akinori Kanai, Suk Min Jang, Khan L. Cox, Bing-Rui Zhou, Sabrina K. Phanor, Yi Zhang, Ruo-Wen Chen, Christopher C. Ebmeier, Catherine Lachance, Maxime Galloy, Amelie Fradet-Turcotte, Martha L. Bulyk, Yawen Bai, Michael G. Poirier, Jacques Côté, Akihiko Yokoyama, Tatiana G. Kutateladze

Nat Commun. 2023; 14: 697. Published online 2023 Feb 8. doi: 10.1038/s41467-023-36368-5

PMCID:: PMC9908889

Abstract Article PDF–12M

Select item 98811369.

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain

Lisa Marie Weber, Yulin Jia, Bastian Stielow, Stephen S Gisselbrecht, Yinghua Cao, Yanpeng Ren, Iris Rohner, Jessica King, Elisabeth Rothman, Sabrina Fischer, Clara Simon, Ignasi Forné, Andrea Nist, Thorsten Stiewe, Martha L Bulyk, Zhanxin Wang, Robert Liefke

Nucleic Acids Res. 2023 Jan 25; 51(2): 574–594. Published online 2022 Dec 20. doi: 10.1093/nar/gkac1188

PMCID:: PMC9881136

Abstract Article PDF–4.4M

Select item 954034510.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 934345511.

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis

Natalie Vaughan, Nico Scholz, Catherine Lindon, Julien D. F. Licchesi

Sci Rep. 2022; 12: 13160. Published online 2022 Aug 1. doi: 10.1038/s41598-022-16965-y

PMCID:: PMC9343455

Abstract Article PDF–3.7M

Select item 929667612.

Matrix stiffness-induced upregulation of histone acetyltransferase KAT6A promotes hepatocellular carcinoma progression through regulating SOX2 expression

Wei Zhao, Huanye Mo, Runkun Liu, Tianxiang Chen, Nan Yang, Zhikui Liu

Br J Cancer. 2022 Jul 20; 127(2): 202–210. Published online 2022 Mar 24. doi: 10.1038/s41416-022-01784-9

PMCID:: PMC9296676

Abstract Article PDF–2.9M

Select item 926261413.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 911973614.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 891603715.

KAT6A and ENL form an epigenetic transcriptional control module to drive critical leukemogenic gene expression programs

Fangxue Yan, Jinyang Li, Jelena Milosevic, Ricardo Petroni, Suying Liu, Zhennan Shi, Salina Yuan, Janice M. Reynaga, Yuwei Qi, Joshua Rico, Sixiang Yu, Yiman Liu, Susumu Rokudai, Neil Palmisiano, Sara E. Meyer, Pamela J Sung, Liling Wan, Fei Lan, Benjamin A. Garcia, Ben Z. Stanger, David B. Sykes, M. Andrés Blanco

Cancer Discov. Author manuscript; available in PMC 2022 Sep 1.

Published in final edited form as: Cancer Discov. 2022 Mar 1; 12(3): 792–811. doi: 10.1158/2159-8290.CD-20-1459

PMCID:: PMC8916037

Abstract Article PDF–2.6M

Select item 852949416.

KAT6A Acetylation of SMAD3 Regulates Myeloid‐Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple‐Negative Breast Cancer

Bo Yu, Fei Luo, Bowen Sun, Wenxue Liu, Qiqi Shi, Shi‐Yuan Cheng, Ceshi Chen, Guoqiang Chen, Yanxin Li, Haizhong Feng

Adv Sci (Weinh) 2021 Oct; 8(20): 2100014. Published online 2021 Aug 13. doi: 10.1002/advs.202100014

Correction in:: Adv Sci (Weinh). 2022 Jan; 9(3): 2105793.

PMCID:: PMC8529494

Abstract Article PDF–4.5M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 812022718.

KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1

Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng

Theranostics. 2021; 11(13): 6278–6292. Published online 2021 Apr 15. doi: 10.7150/thno.57455

PMCID:: PMC8120227

Abstract Article PDF–2.7M

Select item 770266219.

Acute Monoblastic Leukemia with Erythrophagocytosis and Absence of KAT6A Rearrangement

Carlos De Miguel Sánchez, Diego Robles de Castro, Ana Vega González de Viñaspre, Ariane Unamunzaga Zilaurren, Arantza Mendizábal Abad, José María Guinea de Castro

Turk J Haematol. 2020 Dec; 37(4): 282–283. Published online 2020 Nov 19. doi: 10.4274/tjh.galenos.2020.2020.0237

PMCID:: PMC7702662

Article PDF–243K

Select item 746727720.

KAT6A amplifications are associated with shorter progression-free survival and overall survival in patients with endometrial serous carcinoma

Ozlen Saglam, Zhenya Tang, Guilin Tang, L. Jeffrey Medeiros, Gokce A. Toruner

PLoS One. 2020; 15(9): e0238477. Published online 2020 Sep 2. doi: 10.1371/journal.pone.0238477

PMCID:: PMC7467277

Abstract Article PDF–2.8M

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