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Items: 1 to 20 of 104

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
The REEP5/TRAM1 complex binds SARS-CoV-2 NSP3 and promotes virus replication
Jie Li, Qi Gui, Feng-Xia Liang, Joseph Sall, Qingyue Zhang, Yatong Duan, Avantika Dhabaria, Manor Askenazi, Beatrix Ueberheide, Kenneth A. Stapleford, Michele Pagano
J Virol. 2023 Oct; 97(10): e00507-23. Published online 2023 Sep 28. doi: 10.1128/jvi.00507-23
PMCID:
PMC10617467
AbstractArticlePDF–3.2M
3.
The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants
Adam Hosszu, Akos R. Toth, Tamas Lakat, Ganna Stepanova, Zsuzsanna Antal, Laszlo J. Wagner, Attila J. Szabo, Andrea Fekete
Int J Mol Sci. 2023 Jul; 24(14): 11630. Published online 2023 Jul 19. doi: 10.3390/ijms241411630
PMCID:
PMC10380852
AbstractArticlePDF–3.4M
4.
In Vitro Reconstitution and Analysis of SARS-CoV-2/Host Protein–Protein Interactions
Shayli Varasteh Moradi, Yue Wu, Patricia Walden, Zhenling Cui, Wayne A. Johnston, Dmitri Petrov, Kirill Alexandrov
ACS Omega. 2023 Jul 18; 8(28): 25009–25019. Published online 2023 Jul 6. doi: 10.1021/acsomega.3c01625
PMCID:
PMC10357528
AbstractArticlePDF–4.1M
5.
Sig1R activates extracellular matrix-induced bladder cancer cell proliferation and angiogenesis by combing β-integrin
Feng Zhao, Tianli Yang, Liuhua Zhou, Rongfei Li, Jingyu Liu, Jun Zhao, Ruipeng Jia
Aging (Albany NY) 2023 May 31; 15(10): 4182–4201. Published online 2023 May 16. doi: 10.18632/aging.204721
PMCID:
PMC10258007
AbstractArticlePDF–3.0M
6.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
7.
SIGMAR1 Confers Innate Resilience against Neurodegeneration
Simon Couly, Yuko Yasui, Tsung-Ping Su
Int J Mol Sci. 2023 May; 24(9): 7767. Published online 2023 Apr 24. doi: 10.3390/ijms24097767
PMCID:
PMC10178636
AbstractArticlePDF–1.5M
8.
Investigation of the Entry Pathway and Molecular Nature of σ1 Receptor Ligands
Gianmarco Pascarella, Lorenzo Antonelli, Daniele Narzi, Theo Battista, Annarita Fiorillo, Gianni Colotti, Leonardo Guidoni, Veronica Morea, Andrea Ilari
Int J Mol Sci. 2023 Apr; 24(7): 6367. Published online 2023 Mar 28. doi: 10.3390/ijms24076367
PMCID:
PMC10094450
AbstractArticlePDF–4.7M
9.
TRPA1 modulation by Sigma-1 receptor prevents oxaliplatin-induced painful peripheral neuropathy
Aida Marcotti, Jorge Fernández-Trillo, Alejandro González, Marta Vizcaíno-Escoto, Pablo Ros-Arlanzón, Luz Romero, José Miguel Vela, Ana Gomis, Félix Viana, Elvira de la Peña
Brain. 2023 Feb; 146(2): 475–491. Published online 2022 Jul 24. doi: 10.1093/brain/awac273
PMCID:
PMC9924907
AbstractArticlePDF–1.1M
10.
Overview of Sigma-1R Subcellular Specific Biological Functions and Role in Neuroprotection
Véronik Lachance, Sara-Maude Bélanger, Célia Hay, Victoria Le Corvec, Vina Banouvong, Mathieu Lapalme, Khadija Tarmoun, Guillaume Beaucaire, Marc P. Lussier, Saïd Kourrich
Int J Mol Sci. 2023 Feb; 24(3): 1971. Published online 2023 Jan 19. doi: 10.3390/ijms24031971
PMCID:
PMC9916267
AbstractArticlePDF–4.2M
11.
Sigma-1 Receptor Signaling: In Search of New Therapeutic Alternatives for Cardiovascular and Renal Diseases
Francisco Javier Munguia-Galaviz, Alejandra Guillermina Miranda-Diaz, Miguel Alejandro Cardenas-Sosa, Raquel Echavarria
Int J Mol Sci. 2023 Feb; 24(3): 1997. Published online 2023 Jan 19. doi: 10.3390/ijms24031997
PMCID:
PMC9916216
AbstractArticlePDF–3.7M
12.
A comprehensive SARS-CoV-2–human protein–protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets
Yadi Zhou, Yuan Liu, Shagun Gupta, Mauricio I. Paramo, Yuan Hou, Chengsheng Mao, Yuan Luo, Julius Judd, Shayne Wierbowski, Marta Bertolotti, Mriganka Nerkar, Lara Jehi, Nir Drayman, Vlad Nicolaescu, Haley Gula, Savaş Tay, Glenn Randall, Peihui Wang, John T. Lis, Cédric Feschotte, Serpil C. Erzurum, Feixiong Cheng, Haiyuan Yu
Nat Biotechnol. Author manuscript; available in PMC 2023 Jan 20.
Published in final edited form as: Nat Biotechnol. 2023 Jan; 41(1): 128–139. Published online 2022 Oct 10. doi: 10.1038/s41587-022-01474-0
PMCID:
PMC9851973
AbstractArticlePDF–4.0M
13.
SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis
Jun-yi Zhu, Guanglei Wang, Xiaohu Huang, Hangnoh Lee, Jin-Gu Lee, Penghua Yang, Joyce van de Leemput, Weiliang Huang, Maureen A. Kane, Peixin Yang, Zhe Han
Commun Biol. 2022; 5: 1039. Published online 2022 Sep 30. doi: 10.1038/s42003-022-03986-6
PMCID:
PMC9523645
AbstractArticlePDF–3.9M
14.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
15.
Sigma-1 Receptor in Retina: Neuroprotective Effects and Potential Mechanisms
Zifen Xu, Yushuang Lei, Huan Qin, Shiyao Zhang, Ping Li, Kai Yao
Int J Mol Sci. 2022 Jul; 23(14): 7572. Published online 2022 Jul 8. doi: 10.3390/ijms23147572
PMCID:
PMC9321618
AbstractArticlePDF–2.5M
16.
Sigma‐1 receptor attenuates osteoclastogenesis by promoting ER‐associated degradation of SERCA2
Xiaoan Wei, Zeyu Zheng, Zhenhua Feng, Lin Zheng, Siyue Tao, Bingjie Zheng, Bao Huang, Xuyang Zhang, Junhui Liu, Yilei Chen, Wentian Zong, Zhi Shan, Shunwu Fan, Jian Chen, Fengdong Zhao
EMBO Mol Med. 2022 Jul; 14(7): e15373. Published online 2022 May 25. doi: 10.15252/emmm.202115373
PMCID:
PMC9260208
AbstractArticlePDF–3.5M
17.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
18.
Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins
Fabian Hosp, Hannes Vossfeldt, Matthias Heinig, Djordje Vasiljevic, Anup Arumughan, Emanuel Wyler, Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, Markus Landthaler, Norbert Hubner, Erich E. Wanker, Lars Lannfelt, Martin Ingelsson, Maciej Lalowski, Aaron Voigt, Matthias Selbach
Cell Rep. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Cell Rep. 2015 May 19; 11(7): 1134–1146. Published online 2015 May 7. doi: 10.1016/j.celrep.2015.04.030
PMCID:
PMC9014711
AbstractArticlePDF–2.2M
19.
The Sigma-1 receptor is an ER-localized type II membrane protein
Neeraj Sharma, Chaitanya Patel, Marina Shenkman, Amit Kessel, Nir Ben-Tal, Gerardo Z. Lederkremer
J Biol Chem. 2021 Nov; 297(5): 101299. Published online 2021 Oct 11. doi: 10.1016/j.jbc.2021.101299
PMCID:
PMC8561001
AbstractArticlePDF–2.6M
20.
Sigma-1 Receptor Agonists Acting on Aquaporin-Mediated H2O2 Permeability: New Tools for Counteracting Oxidative Stress
Giorgia Pellavio, Giacomo Rossino, Giulia Gastaldi, Daniela Rossi, Pasquale Linciano, Simona Collina, Umberto Laforenza
Int J Mol Sci. 2021 Sep; 22(18): 9790. Published online 2021 Sep 10. doi: 10.3390/ijms22189790
PMCID:
PMC8467392
AbstractArticlePDF–2.6M

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