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Select item 107990631.

Two mitochondrial DNA polymorphisms modulate cardiolipin binding and lead to synthetic lethality

Ason C. Y. Chiang, Jan Ježek, Peiqiang Mu, Ying Di, Anna Klucnika, Martin Jabůrek, Petr Ježek, Hansong Ma

Nat Commun. 2024; 15: 611. Published online 2024 Jan 19. doi: 10.1038/s41467-024-44964-2

PMCID:: PMC10799063

Abstract Article PDF–2.1M

Select item 107182852.

Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity

Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112846. Published online 2023 Jul 29. doi: 10.1016/j.celrep.2023.112846

PMCID:: PMC10718285

Abstract Article PDF–2.8M

Select item 106228403.

Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle

Mindong Ren, Yang Xu, Colin K.L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Michael Schlame

J Biol Chem. 2023 Oct; 299(10): 105241. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105241

PMCID:: PMC10622840

Abstract Article PDF–1.2M

Select item 105295814.

A novel panel of Drosophila TAFAZZIN mutants in distinct genetic backgrounds as a resource for therapeutic testing

Kristin Richardson, Robert Wessells

PLoS One. 2023; 18(9): e0286380. Published online 2023 Sep 27. doi: 10.1371/journal.pone.0286380

PMCID:: PMC10529581

Abstract Article PDF–1.2M

Select item 102159725.

Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation

Hideaki Fujita, Junichi Kaneshiro, Maki Takeda, Kensuke Sasaki, Rikako Yamamoto, Daiki Umetsu, Erina Kuranaga, Shuichiro Higo, Takumi Kondo, Yoshihiro Asano, Yasushi Sakata, Shigeru Miyagawa, Tomonobu M Watanabe

Life Sci Alliance. 2023 Jul; 6(7): e202302070. Published online 2023 May 26. doi: 10.26508/lsa.202302070

PMCID:: PMC10215972

Abstract Article PDF–3.8M

Select item 95586266.

Stimulating the sir2–spargel axis rescues exercise capacity and mitochondrial respiration in a Drosophila model of Barth syndrome

Deena Damschroder, Rubén Zapata-Pérez, Kristin Richardson, Frédéric M. Vaz, Riekelt H. Houtkooper, Robert Wessells

Dis Model Mech. 2022 Oct 1; 15(10): dmm049279. Published online 2022 Oct 5. doi: 10.1242/dmm.049279

Correction in:: Dis Model Mech. 2024 Sep 1; 17(9): dmm052040.

PMCID:: PMC9558626

Abstract Article

Select item 88831787.

NAD supplementation improves mitochondrial performance of cardiolipin mutants

Jiajia Ji, Deena Damschroder, Denise Bessert, Pablo Lazcano, Robert Wessells, Christian A. Reynolds, Miriam L. Greenberg

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Apr; 1867(4): 159094. Published online 2022 Jan 18. doi: 10.1016/j.bbalip.2021.159094

PMCID:: PMC8883178

Abstract Article PDF–1.2M

Select item 86341388.

Cardiolipin remodeling enables protein crowding in the inner mitochondrial membrane

Yang Xu, Hediye Erdjument‐Bromage, Colin K L Phoon, Thomas A Neubert, Mindong Ren, Michael Schlame

EMBO J. 2021 Dec 1; 40(23): e108428. Published online 2021 Oct 18. doi: 10.15252/embj.2021108428

PMCID:: PMC8634138

Abstract Article PDF–1.1M

Select item 84328419.

iPLA₂-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster

Surya Jyoti Banerjee, Adina Schonbrun, Sogol Eizadshenass, Shimshon Benji, Yaakov Tzvi Cantor, Liam Eliach, Matthew Lubin, Zev Narrowe, Jeremy Purow, Benjamin Shulman, Leib Wiener, Josefa Steinhauer

PLoS One. 2021; 16(9): e0256738. Published online 2021 Sep 10. doi: 10.1371/journal.pone.0256738

PMCID:: PMC8432841

Abstract Article PDF–4.9M

Select item 835559910.

Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study

Yesid Cuesta-Astroz, Guilherme Gischkow Rucatti, Leandro Murgas, Carol D. SanMartín, Mario Sanhueza, Alberto J. M. Martin

Front Genet. 2021; 12: 649764. Published online 2021 Jul 28. doi: 10.3389/fgene.2021.649764

PMCID:: PMC8355599

Abstract Article PDF–1.5M

Select item 757659911.

Emerging role of the Hippo pathway in autophagy

Dongying Wang, Jiaxing He, Bingyu Huang, Shanshan Liu, Hongming Zhu, Tianmin Xu

Cell Death Dis. 2020 Oct; 11(10): 880. Published online 2020 Oct 20. doi: 10.1038/s41419-020-03069-6

PMCID:: PMC7576599

Abstract Article PDF–2.3M

Select item 733458012.

Drosophila PTPMT1 Has a Function in Tracheal Air Filling

Amanda M. Papakyrikos, Min Joo Kim, Xinnan Wang

iScience. 2020 Jul 24; 23(7): 101285. Published online 2020 Jun 20. doi: 10.1016/j.isci.2020.101285

PMCID:: PMC7334580

Abstract Article PDF–5.8M

Select item 727233213.

STRIPAK–PP2A regulates Hippo-Yorkie signaling to suppress retinal fate in the Drosophila eye disc peripodial epithelium

Scott J. Neal, Qingxiang Zhou, Francesca Pignoni

J Cell Sci. 2020 May 15; 133(10): jcs237834. Published online 2020 May 26. doi: 10.1242/jcs.237834

PMCID:: PMC7272332

Abstract Article

Select item 703532614.

Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution

Yuxuan Chen, Han Han, Gayoung Seo, Rebecca Elizabeth Vargas, Bing Yang, Kimberly Chuc, Huabin Zhao, Wenqi Wang

Sci Rep. 2020; 10: 3173. Published online 2020 Feb 21. doi: 10.1038/s41598-020-60120-4

PMCID:: PMC7035326

Abstract Article PDF–6.6M

Select item 696157815.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 656127316.

Assembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipin

Yang Xu, Murari Anjaneyulu, Alec Donelian, Wenxi Yu, Miriam L. Greenberg, Mindong Ren, Edward Owusu-Ansah, Michael Schlame

Proc Natl Acad Sci U S A. 2019 Jun 4; 116(23): 11235–11240. Published online 2019 May 20. doi: 10.1073/pnas.1900890116

PMCID:: PMC6561273

Abstract Article PDF–1.0M

Select item 650653917.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 605246318.

Comparative transcriptomics across 14 Drosophila species reveals signatures of longevity

Siming Ma, Andrei S. Avanesov, Emily Porter, Byung Cheon Lee, Marco Mariotti, Nadezhda Zemskaya, Roderic Guigo, Alexey A. Moskalev, Vadim N. Gladyshev

Aging Cell. 2018 Aug; 17(4): e12740. Published online 2018 Apr 19. doi: 10.1111/acel.12740