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Items: 1 to 20 of 346

1.
Targeting IGF1/IGF1r signaling relieve pain and autophagic dysfunction in NTG-induced chronic migraine model of mice
Tianxiao Wang, Chenlu Zhu, Kaibo zhang, Jinggui Gao, Yunhao Xu, Chenyang Duan, Shouyi Wu, Cheng Peng, Jisong Guan, Yonggang Wang
J Headache Pain. 2024; 25(1): 156. Published online 2024 Sep 20. doi: 10.1186/s10194-024-01864-6
Correction in:
J Headache Pain. 2024; 25(1): 173.
PMCID:
PMC11414239
AbstractArticlePDF–8.2M
2.
A role for astrocytic insulin-like growth factor I receptors in the response to ischemic insult
Kentaro Suda, Jaime Pignatelli, Laura Genis, Ana M Fernandez, Estrella Fernandez de Sevilla, Ines Fernandez de la Cruz, Andrea Pozo-Rodrigalvarez, Maria L de Ceballos, Sonia Díaz-Pacheco, Raquel Herrero-Labrador, Ignacio Torres Aleman
J Cereb Blood Flow Metab. 2024 Jun; 44(6): 970–984. Published online 2023 Nov 28. doi: 10.1177/0271678X231217669
PMCID:
PMC11318401
AbstractArticlePDF–1.6M
3.
Mechanism of adipose tissue-derived stromal cell-extracellular vesicles in treating oral submucous fibrosis by blocking the TGF-β1/Smad3 pathway via the miR-760-3p/IGF1R axis
Fengcong Wang, Li Jiang, Ping Liu, Yanjun Jiang
Biomol Biomed. 2024 Aug 1; 24(4): 827–839. Published online 2024 Aug 1. doi: 10.17305/bb.2023.9944
PMCID:
PMC11293217
AbstractArticlePDF–13M
4.
Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin receptor (Insr) genes
Kim Moorwood, Florentia M. Smith, Alastair S. Garfield, Andrew Ward
BMC Biol. 2024; 22: 127. Published online 2024 May 30. doi: 10.1186/s12915-024-01926-w
PMCID:
PMC11140863
AbstractArticlePDF–6.8M
5.
GRP94 is an IGF-1R chaperone and regulates beta cell death in diabetes
Do-Sung Kim, Lili Song, Wenyu Gou, Jisun Kim, Bei Liu, Hua Wei, Robin C. Muise-Helmericks, Zihai Li, Hongjun Wang
Cell Death Dis. 2024 May; 15(5): 374. Published online 2024 May 29. doi: 10.1038/s41419-024-06754-y
PMCID:
PMC11137047
AbstractArticlePDF–3.7M
6.
Normal Ovarian Function in Subfertile Mouse with Amhr2-Cre-Driven Ablation of Insr and Igf1r
Jenna C. Douglas, Nikola Sekulovski, Madison R. Arreola, Yeongseok Oh, Kanako Hayashi, James A. MacLean, II
Genes (Basel) 2024 May; 15(5): 616. Published online 2024 May 12. doi: 10.3390/genes15050616
PMCID:
PMC11121541
AbstractArticlePDF–7.1M
7.
Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects
Lauren R. Miller, Marisa A. Bickel, Michaela L. Vance, Hannah Vaden, Domonkos Nagykaldi, Adam Nyul-Toth, Elizabeth C. Bullen, Tripti Gautam, Stefano Tarantini, Andriy Yabluchanskiy, Tamas Kiss, Zoltan Ungvari, Shannon M. Conley
GeroScience. 2024 Jun; 46(3): 3481–3501. Published online 2024 Feb 23. doi: 10.1007/s11357-024-01090-7
PMCID:
PMC11009188
AbstractArticlePDF–6.6M
8.
Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
Qiang Lan, Ewelina Trela, Riitta Lindström, Jyoti Prabha Satta, Beata Kaczyńska, Mona M Christensen, Martin Holzenberger, Jukka Jernvall, Marja L Mikkola
eLife. 2024; 13: e93326. Published online 2024 Mar 5. doi: 10.7554/eLife.93326
PMCID:
PMC10959526
AbstractArticlePDF–10M
9.
IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice
Lauren R. Miller, Marisa A. Bickel, Stefano Tarantini, Megan E. Runion, Zoe Matacchiera, Michaela L. Vance, Clara Hibbs, Hannah Vaden, Domonkos Nagykaldi, Teryn Martin, Elizabeth C. Bullen, Jessica Pinckard, Tamas Kiss, Eric W. Howard, Andriy Yabluchanskiy, Shannon M. Conley
Front Aging Neurosci. 2024; 16: 1320808. Published online 2024 Feb 15. doi: 10.3389/fnagi.2024.1320808
PMCID:
PMC10902040
AbstractArticlePDF–3.6M
10.
Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function
Kaitlin Kiernan, Yazan Alwarawrah, Amanda G. Nichols, Keiko Danzaki, Nancie J. MacIver
Sci Rep. 2024; 14: 4331. Published online 2024 Feb 21. doi: 10.1038/s41598-024-54836-w
PMCID:
PMC10881490
AbstractArticlePDF–1.7M
11.
IGF-I Receptor Is Required for the Anabolic Actions of Parathyroid Hormone on Bone
Yongmei Wang, Shigeki Nishida, Benjamin M Boudignon, Andrew Burghardt, Hashem Z Elalieh, Michelle M Hamilton, Sharmila Majumdar, Bernard P Halloran, Thomas L Clemens, Daniel D Bikle
J Bone Miner Res. Author manuscript; available in PMC 2023 Dec 7.
Published in final edited form as: J Bone Miner Res. 2007 Sep; 22(9): 1329–1337. doi: 10.1359/jbmr.070517
PMCID:
PMC10702248
AbstractArticlePDF–1.2M
12.
Insulin-Like Growth Factor-I Is Essential for Embryonic Bone Development
Yongmei Wang, Shigeki Nishida, Takeshi Sakata, Hashem Z. Elalieh, Wenhan Chang, Bernard P. Halloran, Steven B. Doty, Daniel D. Bikle
Endocrinology. Author manuscript; available in PMC 2023 Nov 14.
Published in final edited form as: Endocrinology. 2006 Oct; 147(10): 4753–4761. Published online 2006 Jul 20. doi: 10.1210/en.2006-0196
PMCID:
PMC10645399
AbstractArticlePDF–2.8M
13.
The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway
Xiang Xiong, Liqin Yuan, Kai Yang, Xiancheng Wang
J Transl Med. 2023; 21: 732. Published online 2023 Oct 17. doi: 10.1186/s12967-023-04581-x
PMCID:
PMC10583486
AbstractArticlePDF–9.6M
14.
IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy
Li Pan, Kin-Sang Cho, Xin Wei, Fuyi Xu, Anton Lennikov, Guangan Hu, Jing Tang, Shuai Guo, Julie Chen, Emil Kriukov, Robert Kyle, Farris Elzaridi, Shuhong Jiang, Pierre A. Dromel, Michael Young, Petr Baranov, Do Chi-Wai, Robert W. Williams, Jianzhu Chen, Lu Lu, Dong Feng Chen
Cell Rep. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112889. Published online 2023 Jul 31. doi: 10.1016/j.celrep.2023.112889
PMCID:
PMC10528709
AbstractArticlePDF–3.4M
15.
Blocking insulin-like growth factor 1 receptor signaling pathway inhibits neuromuscular junction regeneration after botulinum toxin-A treatment
Hiroki Ishihara, Yoshinori Otani, Kazuki Tanaka, Hisao Miyajima, Huy Xuan Ngo, Masashi Fujitani
Cell Death Dis. 2023 Sep; 14(9): 609. Published online 2023 Sep 16. doi: 10.1038/s41419-023-06128-w
PMCID:
PMC10505167
AbstractArticlePDF–4.0M
16.
Insulin-like Growth Factor 1, Growth Hormone, and Anti-Müllerian Hormone Receptors Are Differentially Expressed during GnRH Neuron Development
Alyssa J. J. Paganoni, Rossella Cannarella, Roberto Oleari, Federica Amoruso, Renata Antal, Marco Ruzza, Chiara Olivieri, Rosita A. Condorelli, Sandro La Vignera, Fationa Tolaj, Anna Cariboni, Aldo E. Calogero, Paolo Magni
Int J Mol Sci. 2023 Sep; 24(17): 13073. Published online 2023 Aug 22. doi: 10.3390/ijms241713073
PMCID:
PMC10487694
AbstractArticlePDF–8.8M
17.
Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation
Cornelis J. Boogerd, Ilaria Perini, Eirini Kyriakopoulou, Su Ji Han, Phit La, Britt van der Swaan, Jari B. Berkhout, Danielle Versteeg, Jantine Monshouwer-Kloots, Eva van Rooij
Nat Commun. 2023; 14: 4716. Published online 2023 Aug 5. doi: 10.1038/s41467-023-40203-2
PMCID:
PMC10404286
AbstractArticlePDF–3.4M
18.
EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis
Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerrero, Antonio Llombart-Bosch, Isidro Machado, Katia Scotlandi, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, M. Jordan Rowley, Vimla Band, Bhopal C. Mohapatra, Hamid Band
Commun Biol. 2023; 6: 758. Published online 2023 Jul 20. doi: 10.1038/s42003-023-05125-1
PMCID:
PMC10359273
AbstractArticlePDF–9.8M
19.
Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells
Kanako Iwasaki, Benjamin Lalani, Jiho Kahng, Priscila Carapeto, Stephanie Sanjines, Francesko Hela, Cristian Abarca, Tadataka Tsuji, Justin Darcy, Andrzej Bartke, Yu-Hua Tseng, Rohit N. Kulkarni, Cristina Aguayo-Mazzucato
Front Endocrinol (Lausanne) 2023; 14: 1203534. Published online 2023 Jun 27. doi: 10.3389/fendo.2023.1203534
PMCID:
PMC10335398
AbstractArticlePDF–2.2M
20.
Insulin-like growth factor 1 regulates excitatory synaptic transmission in pyramidal neurons from adult prefrontal cortex
Shuwen Yue, Yunwanbin Wang, Zi-Jun Wang
Neuropharmacology. Author manuscript; available in PMC 2023 Jul 10.
Published in final edited form as: Neuropharmacology. 2022 Oct 1; 217: 109204. Published online 2022 Aug 2. doi: 10.1016/j.neuropharm.2022.109204
PMCID:
PMC10332249
AbstractArticlePDF–1.6M

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