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Select item 104573421.

PINK1 and Parkin regulate IP₃R-mediated ER calcium release

Su Jin Ham, Heesuk Yoo, Daihn Woo, Da Hyun Lee, Kyu-Sang Park, Jongkyeong Chung

Nat Commun. 2023; 14: 5202. Published online 2023 Aug 25. doi: 10.1038/s41467-023-40929-z

PMCID:: PMC10457342

Abstract Article PDF–3.1M

Select item 101057362.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 98461503.

The calcineurin regulator Sarah enables distinct forms of homeostatic plasticity at the Drosophila neuromuscular junction

Noah S. Armstrong, C. Andrew Frank

Front Synaptic Neurosci. 2022; 14: 1033743. Published online 2023 Jan 4. doi: 10.3389/fnsyn.2022.1033743

PMCID:: PMC9846150

Abstract Article PDF–9.4M

Select item 92738684.

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov

Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017

PMCID:: PMC9273868

Abstract Article PDF–3.6M

Select item 88959895.

Transgenic Drosophila lines for LexA-dependent gene and growth regulation

Kathleen R Chang, Deborah D Tsao, Celine Bennett, Elaine Wang, Jax F Floyd, Ashley S Y Tay, Emily Greenwald, Ella S Kim, Catherine Griffin, Elizabeth Morse, Townley Chisholm, Anne E Rankin, Luis Alberto Baena-Lopez, Nicole Lantz, Elizabeth Fox, Lutz Kockel, Seung K Kim, Sangbin Park

G3 (Bethesda) 2022 Mar; 12(3): jkac018. Published online 2022 Jan 19. doi: 10.1093/g3journal/jkac018

PMCID:: PMC8895989

Abstract Article PDF–1.0M

Select item 87944706.

A phosphoswitch at acinus-serine⁴³⁷ controls autophagic responses to cadmium exposure and neurodegenerative stress

Nilay Nandi, Zuhair Zaidi, Charles Tracy, Helmut Krämer

eLife. 2022; 11: e72169. Published online 2022 Jan 17. doi: 10.7554/eLife.72169

PMCID:: PMC8794470

Abstract Article PDF–5.3M

Select item 84918767.

Minibrain kinase and calcineurin coordinate activity-dependent bulk endocytosis through synaptojanin

Yi-Jheng Peng, Junhua Geng, Ying Wu, Cristian Pinales, Jennifer Langen, Yen-Ching Chang, Christopher Buser, Karen T. Chang

J Cell Biol. 2021 Dec 6; 220(12): e202011028. Published online 2021 Oct 1. doi: 10.1083/jcb.202011028

PMCID:: PMC8491876

Abstract Article PDF–7.6M

Select item 75501928.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 71014289.

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Patricia Deng, Anzer Khan, Dionna Jacobson, Nagraj Sambrani, Leeanne McGurk, Xianghua Li, Aswathy Jayasree, Jan Hejatko, Galit Shohat-Ophir, Mary A. O’Connell, Jin Billy Li, Liam P. Keegan

Nat Commun. 2020; 11: 1580. Published online 2020 Mar 27. doi: 10.1038/s41467-020-15435-1

PMCID:: PMC7101428

Abstract Article PDF–1.6M

Select item 696157810.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 662341511.

Calcineurin and Its Regulator Sra/DSCR1 Are Essential for Sleep in Drosophila

Yasuhiro Nakai, Junjiro Horiuchi, Manabu Tsuda, Satomi Takeo, Shin Akahori, Takashi Matsuo, Kazuhiko Kume, Toshiro Aigaki

J Neurosci. 2011 Sep 7; 31(36): 12759–12766. doi: 10.1523/JNEUROSCI.1337-11.2011

PMCID:: PMC6623415

Abstract Article PDF–1.8M

Select item 662325212.

Pan-Neuronal Knockdown of Calcineurin Reduces Sleep in the Fruit Fly, Drosophila melanogaster

Jun Tomita, Madoka Mitsuyoshi, Taro Ueno, Yoshinori Aso, Hiromu Tanimoto, Yasuhiro Nakai, Toshiro Aigaki, Shoen Kume, Kazuhiko Kume

J Neurosci. 2011 Sep 14; 31(37): 13137–13146. doi: 10.1523/JNEUROSCI.5860-10.2011

PMCID:: PMC6623252

Abstract Article PDF–3.3M

Select item 651053113.

Glial Ca²⁺signaling links endocytosis to K⁺ buffering around neuronal somas to regulate excitability

Shirley Weiss, Jan E Melom, Kiel G Ormerod, Yao V Zhang, J Troy Littleton

eLife. 2019; 8: e44186. Published online 2019 Apr 26. doi: 10.7554/eLife.44186

PMCID:: PMC6510531

Abstract Article PDF–5.3M

Select item 642724014.

Calcineurin-dependent Protein Phosphorylation Changes During Egg Activation in Drosophila melanogaster

Zijing Zhang, Yasir H. Ahmed-Braimah, Michael L. Goldberg, Mariana F. Wolfner

Mol Cell Proteomics. 2019 Mar 15; 18(Suppl 1): S145–S158. Published online 2018 Nov 26. doi: 10.1074/mcp.RA118.001076

PMCID:: PMC6427240

Abstract Article PDF–1.5M

Select item 607860415.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352