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Select item 88264841.

A Population Genomic Assessment of Three Decades of Evolution in a Natural Drosophila Population

Jeremy D Lange, Héloïse Bastide, Justin B Lack, John E Pool

Mol Biol Evol. 2022 Feb; 39(2): msab368. Published online 2021 Dec 31. doi: 10.1093/molbev/msab368

PMCID:: PMC8826484

Abstract Article PDF–864K

Select item 80229462.

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

Diane P V Lebo, Alice Chirn, Jeffrey D Taylor, Andre Levan, Valentina Doerre Torres, Emily Agreda, Sandy B Serizier, Allison K Lord, Victoria K Jenkins, Kimberly McCall

G3 (Bethesda) 2021 Feb; 11(2): jkaa066. Published online 2021 Mar 6. doi: 10.1093/g3journal/jkaa066

PMCID:: PMC8022946

Abstract Article PDF–1.3M

Select item 65482273.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 60278804.

Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure

Richard D. Mortensen, Regan P. Moore, Stephanie M. Fogerson, Hellen Y. Chiou, Chimdindu V. Obinero, Neel K. Prabhu, Angela H. Wei, Janice M. Crawford, Daniel P. Kiehart

G3 (Bethesda) 2018 Jul; 8(7): 2361–2387. Published online 2018 May 18. doi: 10.1534/g3.118.200233

PMCID:: PMC6027880

Abstract Article PDF–7.5M

Select item 59313695.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 57078056.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890027.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 45283308.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 45283299.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288710.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 420866711.

Combining Genetic Perturbations and Proteomics to Examine Kinase-Phosphatase Networks in Drosophila Embryos

Richelle Sopko, Marianna Foos, Arunachalam Vinayagam, Bo Zhai, Richard Binari, Yanhui Hu, Sakara Randklev, Lizabeth A. Perkins, Steven P. Gygi, Norbert Perrimon

Dev Cell. Author manuscript; available in PMC 2015 Oct 13.

Published in final edited form as: Dev Cell. 2014 Oct 13; 31(1): 114–127. Published online 2014 Oct 2. doi: 10.1016/j.devcel.2014.07.027

PMCID:: PMC4208667

Abstract Article PDF–2.4M

Select item 386985312.

An Allele of Sequoia Dominantly Enhances a Trio Mutant Phenotype to Influence Drosophila Larval Behavior

Kathryn E. Dean, April Fields, Marcus J. Geer, Eric C. King, Brian T. Lynch, Rohan R. Manohar, Julianne R. McCall, Katherine C. Palozola, Yan Zhang, Eric C. Liebl

PLoS One. 2013; 8(12): e84149. Published online 2013 Dec 20. doi: 10.1371/journal.pone.0084149

PMCID:: PMC3869853

Abstract Article PDF–1.9M

Select item 386112813.

Alcohol-Induced Histone Acetylation Reveals a Gene Network Involved in Alcohol Tolerance

Alfredo Ghezzi, Harish R. Krishnan, Linda Lew, Francisco J. Prado, III, Darryl S. Ong, Nigel S. Atkinson

PLoS Genet. 2013 Dec; 9(12): e1003986. Published online 2013 Dec 12. doi: 10.1371/journal.pgen.1003986

PMCID:: PMC3861128

Abstract Article PDF–972K

Select item 362032214.

Modulation of Morphogenesis by Egfr during Dorsal Closure in Drosophila

Weiping Shen, Xi Chen, Olga Cormier, David Chung-Pei Cheng, Bruce Reed, Nicholas Harden

PLoS One. 2013; 8(4): e60180. Published online 2013 Apr 8. doi: 10.1371/journal.pone.0060180

PMCID:: PMC3620322

Abstract Article PDF–20M

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946716.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 343913617.

Proteomic and Functional Genomic Landscape of Receptor Tyrosine Kinase and Ras to Extracellular Signal–Regulated Kinase Signaling

Adam A. Friedman, George Tucker, Rohit Singh, Dong Yan, Arunachalam Vinayagam, Yanhui Hu, Richard Binari, Pengyu Hong, Xiaoyun Sun, Maura Porto, Svetlana Pacifico, Thilakam Murali, Russell L. Finley, Jr., John M. Asara, Bonnie Berger, Norbert Perrimon

Sci Signal. Author manuscript; available in PMC 2012 Sep 11.

Published in final edited form as: Sci Signal. 2011 Oct 25; 4(196): rs10. Published online 2011 Oct 25. doi: 10.1126/scisignal.2002029

PMCID:: PMC3439136

Abstract Article PDF–2.4M

Select item 335508518.

Drosophila Activated Cdc42 Kinase Has an Anti-Apoptotic Function

Jessica A. Schoenherr, J. Michelle Drennan, Juan S. Martinez, Madhusudana Rao Chikka, Mark C. Hall, Henry C. Chang, James C. Clemens

PLoS Genet. 2012 May; 8(5): e1002725. Published online 2012 May 17. doi: 10.1371/journal.pgen.1002725

PMCID:: PMC3355085

Abstract Article PDF–8.9M

Select item 305899419.

E2 Ligase dRad6 Regulates DMP53 Turnover in Drosophila

Su Chen, Hui-Min Wei, Wen-Wen Lv, Da-Liang Wang, Fang-Lin Sun

J Biol Chem. 2011 Mar 18; 286(11): 9020–9030. Published online 2011 Jan 4. doi: 10.1074/jbc.M110.190314

PMCID:: PMC3058994

Abstract Article PDF–1.9M

Select item 304044120.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

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