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Select item 114874991.

SPOCK: Master regulator of malignant tumors (Review)

Mingyuan Xiao, Jiancheng Xue, Enli Jin

Mol Med Rep. 2024 Dec; 30(6): 231. Published online 2024 Oct 8. doi: 10.3892/mmr.2024.13355

PMCID:: PMC11487499

Abstract Article PDF–2.9M

Select item 111094832.

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors

Anita Waltho, Oliver Popp, Christopher Lenz, Lukas Pluska, Mahil Lambert, Volker Dötsch, Philipp Mertins, Thomas Sommer

Life Sci Alliance. 2024 Aug; 7(8): e202402740. Published online 2024 May 21. doi: 10.26508/lsa.202402740

PMCID:: PMC11109483

Abstract Article PDF–2.9M

Select item 107170423.

SPOCK1, as a potential prognostic and therapeutic biomarker for lung adenocarcinoma, is associated with epithelial-mesenchymal transition and immune evasion

Yafeng Liu, Tao Han, Jing Wu, Jiawei Zhou, Jianqiang Guo, Rui Miao, Zhi Xu, Yingru Xing, Ying Bai, Dong Hu

J Transl Med. 2023; 21: 909. Published online 2023 Dec 12. doi: 10.1186/s12967-023-04616-3

PMCID:: PMC10717042

Abstract Article PDF–21M

Select item 99137954.

Proteoglycan SPOCK1 as a Poor Prognostic Marker Promotes Malignant Progression of Clear Cell Renal Cell Carcinoma via Triggering the Snail/Slug-MMP-2 Axis-Mediated Epithelial-to-Mesenchymal Transition

Yung-Wei Lin, Yu-Ching Wen, Chi-Hao Hsiao, Feng-Ru Lai, Shun-Fa Yang, Yi-Chieh Yang, Kuo-Hao Ho, Feng-Koo Hsieh, Michael Hsiao, Wei-Jiunn Lee, Ming-Hsien Chien

Cells. 2023 Feb; 12(3): 352. Published online 2023 Jan 17. doi: 10.3390/cells12030352

PMCID:: PMC9913795

Abstract Article PDF–3.7M

Select item 98265815.

SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer

Caiqin Gan, Mengting Li, Yuanyuan Lu, Ganjing Peng, Wenjie Li, Haizhou Wang, Yanan Peng, Qian Hu, Wanhui Wei, Fan Wang, Lan Liu, Qiu Zhao

BMC Gastroenterol. 2023; 23: 4. Published online 2023 Jan 7. doi: 10.1186/s12876-022-02621-2

PMCID:: PMC9826581

Abstract Article PDF–11M

Select item 92316236.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 88635907.

Expression and Potential Prognostic Value of SOX9, MCL-1 and SPOCK1 in Gastric Adenocarcinoma

Wenyi Luo, Teddy S. Nagaria, Hongxia Sun, Junsheng Ma, Jamie L. Lombardo, Roland Bassett, Austin C. Cao, Dongfeng Tan

Pathol Oncol Res. 2022; 28: 1610293. Published online 2022 Feb 9. doi: 10.3389/pore.2022.1610293

PMCID:: PMC8863590

Abstract Article PDF–1.5M

Select item 82917888.

Long non-coding RNA TTN antisense RNA 1 facilitates hepatocellular carcinoma progression via regulating miR-139-5p/SPOCK1 axis

Xinghao Zhu, Shiqing Jiang, Zongyao Wu, Tonghua Liu, Wei Zhang, Lili Wu, Lijun Xu, Mingliang Shao

Bioengineered. 2021; 12(1): 578–588. Published online 2021 Feb 8. doi: 10.1080/21655979.2021.1882133

PMCID:: PMC8291788

Abstract Article PDF–3.0M

Select item 82368079.

Multiomic analysis of the function of SPOCK1 across cancers: an integrated bioinformatics approach

Jie Han, Yihui Rong, Xudong Gao

J Int Med Res. 2021 Jun; 49(6): 0300060520962659. Published online 2021 Jun 22. doi: 10.1177/0300060520962659

PMCID:: PMC8236807

Abstract Article PDF–1.5M

Select item 783868610.

Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway

Ping Zhao, Hai-Tao Guan, Zhi-Jun Dai, Yu-Guang Ma, Xiao-Xu Liu, Xi-Jing Wang

Oncol Res. 2016; 24(6): 437–445. Published online 2016 Oct 27. doi: 10.3727/096504016X14685034103554

PMCID:: PMC7838686

Abstract Article PDF–7.6M

Select item 783506111.

SPOCK1/SIX1axis promotes breast cancer progression by activating AKT/mTOR signaling

Ming Xu, Xianglan Zhang, Songnan Zhang, Junjie Piao, Yang Yang, Xinyue Wang, Zhenhua Lin

Aging (Albany NY) 2021 Jan 15; 13(1): 1032–1050. Published online 2020 Dec 3. doi: 10.18632/aging.202231

PMCID:: PMC7835061

Abstract Article PDF–3.7M

Select item 776321812.

The Central Region of Testican-2 Forms a Compact Core and Promotes Cell Migration

Anja Krajnc, Aljaž Gaber, Brigita Lenarčič, Miha Pavšič

Int J Mol Sci. 2020 Dec; 21(24): 9413. Published online 2020 Dec 10. doi: 10.3390/ijms21249413

PMCID:: PMC7763218

Abstract Article PDF–8.1M

Select item 773016713.

Divide-and-Conquer Matrisome Protein (DC-MaP) Strategy: An MS-Friendly Approach to Proteomic Matrisome Characterization

Emna Ouni, Sébastien Pyr dit Ruys, Marie-Madeleine Dolmans, Gaëtan Herinckx, Didier Vertommen, Christiani A. Amorim

Int J Mol Sci. 2020 Dec; 21(23): 9141. Published online 2020 Nov 30. doi: 10.3390/ijms21239141

PMCID:: PMC7730167

Abstract Article PDF–8.9M

Select item 752370614.

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis

Katrin Tiemann, Carolina Garri, Sang Bok Lee, Paymaneh D. Malihi, Mincheol Park, Ruth M. Alvarez, Li Peng Yap, Parag Mallick, Jonathan E. Katz, Mitchell E. Gross, Kian Kani

Oncogene. Author manuscript; available in PMC 2020 Sep 29.

Published in final edited form as: Oncogene. 2019 Apr; 38(16): 3003–3018. Published online 2018 Dec 21. doi: 10.1038/s41388-018-0638-9

PMCID:: PMC7523706

Abstract Article PDF–2.3M

Select item 730001115.

SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth

Rehab Alshargabi, Tomomi Sano, Akiko Yamashita, Aiko Takano, Taiki Sanada, Misaki Iwashita, Takanori Shinjo, Takao Fukuda, Terukazu Sanui, Shosei Kishida, Fusanori Nishimura

Sci Rep. 2020; 10: 9785. Published online 2020 Jun 17. doi: 10.1038/s41598-020-66660-z

PMCID:: PMC7300011

Abstract Article PDF–6.5M

Select item 716998316.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 700197917.

3D mapping of native extracellular matrix reveals cellular responses to the microenvironment

Zipora Lansky, Yael Mutsafi, Lothar Houben, Tal Ilani, Gad Armony, Sharon G. Wolf, Deborah Fass

J Struct Biol X. 2019 Jan-Mar; 1: 100002. Published online 2018 Dec 19. doi: 10.1016/j.yjsbx.2018.100002

PMCID:: PMC7001979

Abstract Article PDF–12M

Select item 677813718.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 643365719.

MiR‐139‐5p, miR‐940 and miR‐193a‐5p inhibit the growth of hepatocellular carcinoma by targeting SPOCK1

Peng Li, Zhiwei Xiao, Jiajun Luo, Yaojun Zhang, Lizhu Lin

J Cell Mol Med. 2019 Apr; 23(4): 2475–2488. Published online 2019 Feb 1. doi: 10.1111/jcmm.14121

PMCID:: PMC6433657

Abstract Article PDF–3.1M

Select item 578386720.

SPOCK1 promotes the invasion and metastasis of gastric cancer through Slug‐induced epithelial‐mesenchymal transition

Dehu Chen, Haihua Zhou, Guiyuan Liu, Yinghai Zhao, Gan Cao, Qinghong Liu

J Cell Mol Med. 2018 Feb; 22(2): 797–807. Published online 2017 Sep 22. doi: 10.1111/jcmm.13357

PMCID:: PMC5783867

Abstract Article PDF–1.1M

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