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Select item 112242941.

SOCS1 and SOCS3 as key checkpoint molecules in the immune responses associated to skin inflammation and malignant transformation

Martina Morelli, Stefania Madonna, Cristina Albanesi

Front Immunol. 2024; 15: 1393799. Published online 2024 Jun 21. doi: 10.3389/fimmu.2024.1393799

PMCID:: PMC11224294

Abstract Article PDF–1.4M

Select item 111786082.

Unmasking early colorectal cancer clues: in silico and in vitro investigation of downregulated IGF2, SOCS1, MLH1, and CACNA1G in SSA polyps

Seyedeh Nasim Mirbahari, Nayeralsadat Fatemi, Sanaz Savabkar, Vahid Chaleshi, Neda Zali, Mohammad Yaghoob Taleghani, Ebrahim Mirzaei, Leili Rejali, Pardis Ketabi Moghadam, Ehsan Nazemalhosseini Mojarad

Mol Biol Rep. 2024; 51(1): 764. Published online 2024 Jun 14. doi: 10.1007/s11033-024-09683-3

PMCID:: PMC11178608

Abstract Article PDF–2.9M

Select item 111132993.

Suppressor of cytokine signaling 1 blocks mitosis in human melanoma cells

Verónica Parrillas, Laura Martínez-Muñoz, Borja L. Holgado, Amit Kumar, Graciela Cascio, Pilar Lucas, José Miguel Rodríguez-Frade, Marcos Malumbres, Ana C. Carrera, Karel HM van Wely, Mario Mellado

Cell Mol Life Sci. 2013 Feb; 70(3): 545–558. Published online 2012 Sep 23. doi: 10.1007/s00018-012-1145-8

PMCID:: PMC11113299

Abstract Article PDF–668K

Select item 111033874.

The Role of JAK-STAT-SOCS1 Axis in Tumorigenesis, Malignant Progression and Lymphatic Metastasis of Penile Cancer

Da-Ming Xu, Ling-Xiao Chen, Xiao-Yu Zhuang, Hui Han, Miao Mo

Int J Med Sci. 2024; 21(6): 1176–1186. Published online 2024 Apr 29. doi: 10.7150/ijms.95490

PMCID:: PMC11103387

Abstract Article PDF–7.7M

Select item 109873945.

In cis “benign” SOCS1 variants linked to enhanced interferon signaling and autoimmunity

Yan Du, Kailey Brodeur, Evan Hsu, Liang Chen, Qian Chen, Meng Liu, Qi Cheng, Seymour Rosen, Thomas F. Michniacki, Janet Chou, Mindy S. Lo, Craig D. Platt, Pui Y. Lee

J Autoimmun. Author manuscript; available in PMC 2024 Nov 1.

Published in final edited form as: J Autoimmun. 2023 Nov; 140: 103119. Published online 2023 Oct 4. doi: 10.1016/j.jaut.2023.103119

PMCID:: PMC10987394

Abstract Article PDF–1.8M

Select item 109506986.

IL-13 facilitates ferroptotic death in asthmatic epithelial cells via SOCS1-mediated ubiquitinated degradation of SLC7A11

Manli Miao, Min Pan, Xu Chen, Jiapan Shen, Ling Zhang, Xiaoxia Feng, Mengting Chen, Guofeng Cui, Huaiyuan Zong, Wen Zhang, Shuang Chang, Fangzhou Xu, Zixi Wang, Dapeng Li, Weiwei Liu, Zhao Ding, Shengquan Zhang, Biao Chen, Xiaojun Zha, Xiaoyun Fan

Redox Biol. 2024 May; 71: 103100. Published online 2024 Mar 8. doi: 10.1016/j.redox.2024.103100

PMCID:: PMC10950698

Abstract Article PDF–25M

Select item 109122707.

Downregulation of lncRNA CDKN2B-AS1 attenuates inflammatory response in mice with allergic rhinitis by regulating miR-98-5p/SOCS1 axis

Bangyu Deng, Yunxia zhao, Jisheng Liu

Funct Integr Genomics. 2024; 24(2): 48. Published online 2024 Mar 4. doi: 10.1007/s10142-024-01318-x

PMCID:: PMC10912270

Abstract Article PDF–4.0M

Select item 105093118.

KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammation

Karina C. Lockwood, Travis B. Lear, Shristi Rajbhandari, Alison C. McKelvey, Sarah R. Dunn, Áine N. Boudreau, Yuan Liu, Bill B. Chen

FEBS J. Author manuscript; available in PMC 2023 Sep 28.

Published in final edited form as: FEBS J. 2023 Aug; 290(15): 3802–3811. Published online 2023 Apr 7. doi: 10.1111/febs.16780

PMCID:: PMC10509311

Abstract Article PDF–1.6M

Select item 105003089.

Gold nanoparticles attenuate the interferon-γ induced SOCS1 expression and activation of NF-κB p65/50 activity via modulation of microRNA-155-5p in triple-negative breast cancer cells

Aisha Farhana, Abdullah Alsrhani, Naila Rasheed, Zafar Rasheed

Front Immunol. 2023; 14: 1228458. Published online 2023 Aug 31. doi: 10.3389/fimmu.2023.1228458

PMCID:: PMC10500308

Abstract Article PDF–6.0M

Select item 1024788910.

SARS-CoV2 infection induce miR-155 expression and skewed Th17/Treg balance by changing SOCS1 level: A clinical study

Mohammad Sadegh Soltani-Zangbar, Mahsa Hajivalili, Danyal Daneshdoust, Sara Ghadir, Golaleh Savari, Mohammadali Zolfaghari, Leili Aghebati-Maleki, Solmaz Oloufi, Narjes Nouri, Naser Amini, Amir Mehdizadeh, Hossein Ghasemi Moghadam, Ata Mahmoodpoor, Javad Ahmadian Heris, Mehdi Yousefi

Cytokine. 2023 Sep; 169: 156248. Published online 2023 Jun 8. doi: 10.1016/j.cyto.2023.156248

PMCID:: PMC10247889

Abstract Article PDF–2.3M

Select item 1017774111.

The suppressor of cytokine signaling-1 (SOCS1) gene polymorphism and promoter methylation correlate with the course of COVID-19

Tufan Tukek, Sacide Pehlivan, Alpay Medetalibeyoglu, Istemi Serin, Yasemin Oyacı, Huzeyfe Arıcı, Naci Senkal, Mustafa Pehlivan, Ummuhan Isoglu-Alkac, Murat Kose

Pathog Glob Health. 2023; 117(4): 392–400. Published online 2022 Nov 29. doi: 10.1080/20477724.2022.2151861

PMCID:: PMC10177741

Abstract Article PDF–1.6M

Select item 982742312.

Growth hormone inhibits the JAK/STAT3 pathway by regulating SOCS1 in endometrial cells in vitro: A clue to enhance endometrial receptivity in recurrent implantation failure

Haixia Li, Ning Su, Yaqiao Zhu, Wei Wang, Meihong Cai, Xiaohuan Luo, Wei Xia, Song Quan

Eur J Histochem. 2023 Jan 2; 67(1): 3580. Published online 2022 Dec 22. doi: 10.4081/ejh.2023.3580

PMCID:: PMC9827423

Abstract Article PDF–1.2M

Select item 981730213.

Alterations of SOCS1 and SOCS3 transcript levels, but not promoter methylation levels in subcutaneous adipose tissues in obese women

Solaleh Emamgholipour, Fataneh Esmaeili, Maryam Shabani, Seyedeh Zahra Hasanpour, Mahsa Pilehvari, Hossein Zabihi-Mahmoudabadi, Meysam Motevasseli, Mehrnoosh Shanaki

BMC Endocr Disord. 2023; 23: 7. Published online 2023 Jan 6. doi: 10.1186/s12902-022-01247-5

PMCID:: PMC9817302

Abstract Article PDF–1.2M

Select item 979777814.

MiR-222-3p Aggravates the Inflammatory Response by Targeting SOCS1 to Activate STAT3 Signaling in Ulcerative Colitis

Fei Xia, Wenxia Bo, Jinli Ding, Yanqiu Yu, Jianning Wang

Turk J Gastroenterol. 2022 Nov; 33(11): 934–944. Published online 2022 Nov 1. doi: 10.5152/tjg.2022.21769

PMCID:: PMC9797778

Abstract Article PDF–2.4M

Select item 932026115.

The Effect of Host miRNAs on Prognosis in COVID-19: miRNA-155 May Promote Severity via Targeting Suppressor of Cytokine Signaling 1 (SOCS1) Gene

Asuman Gedikbasi, Gokhan Adas, Nilgun Isiksacan, Kadriye Kart Yasar, Esra Canbolat Unlu, Rabia Yilmaz, Gulsum Oya Hergunsel, Zafer Cukurova

Genes (Basel) 2022 Jul; 13(7): 1146. Published online 2022 Jun 25. doi: 10.3390/genes13071146

PMCID:: PMC9320261

Abstract Article PDF–1.5M

Select item 931350316.

Multiomics Analysis Identifies SOCS1 as Restraining T Cell Activation and Preventing Graft‐Versus‐Host Disease

Huidong Guo, Ruifeng Li, Ming Wang, Yingping Hou, Shuoshuo Liu, Ting Peng, Xiang‐Yu Zhao, Liming Lu, Yali Han, Yiming Shao, Ying‐Jun Chang, Cheng Li, Xiao‐Jun Huang

Adv Sci (Weinh) 2022 Jul; 9(21): 2200978. Published online 2022 May 18. doi: 10.1002/advs.202200978