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Items: 1 to 20 of 150

1.
Reciprocal negative feedback regulation of ATF6α and PTEN promotes prostate cancer progression
Tingting Feng, Ru Zhao, Hanwen Zhang, Feifei Sun, Jing Hu, Meng Wang, Mei Qi, Ling Liu, Lin Gao, Yabo Xiao, Junhui Zhen, Weiwen Chen, Lin Wang, Bo Han
Cell Mol Life Sci. 2023 Oct; 80(10): 292. Published online 2023 Sep 16. doi: 10.1007/s00018-023-04940-3
PMCID:
PMC11073217
AbstractArticlePDF–7.3M
2.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
3.
KCNH2A561V Heterozygous Mutation Inhibits KCNH2 Protein Expression via The Activation of UPR Mediated by ATF6
Bangsheng CHEN, Lian TAN, Danqi CHEN, Xinghou WANG, Jiequan LIU, Xiaoyan HUANG, Ying WANG, Shuaishuai HUANG, Feiyan MAO, Jiangfang LIAN
Physiol Res. 2023 Oct; 72(5): 621–631. Published online 2023 Oct 31. doi: 10.33549/physiolres.935095
PMCID:
PMC10751050
AbstractArticlePDF–1.6M
4.
Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF6
Hibiki Koba, Shengyu Jin, Nanami Imada, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Tetsushi Sakuma, Takashi Yamamoto, Kazutoshi Mori
Cell Struct Funct. 2020; 45(1): 9–21. Published online 2019 Dec 19. doi: 10.1247/csf.19030
PMCID:
PMC10739154
AbstractArticlePDF–1.3M
5.
Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation
Dandan Wu, Xing Zhang, Kourtney M. Zimmerly, Ruoning Wang, Chunqing Wang, Russell Hunter, Xiang Wu, Matthew Campen, Meilian Liu, Xuexian O. Yang
Mucosal Immunol. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Mucosal Immunol. 2023 Aug; 16(4): 499–512. Published online 2023 May 19. doi: 10.1016/j.mucimm.2023.05.007
PMCID:
PMC10530451
AbstractArticlePDF–2.4M
6.
Targeting the ATF6-mediated ER stress response and autophagy blocks integrin-driven prostate cancer progression
Amanda J. Macke, Artem N. Pachikov, Taylor E. Divita, Mary E. Morris, Chad A. LaGrange, Melissa S. Holzapfel, Anatoly V. Kubyshkin, Evgeniya Y. Zyablitskaya, Tatiana P. Makalish, Sergey N. Eremenko, Haowen Qiu, Jean-Jack M. Riethoven, George P. Hemstreet, and Armen Petrosyan
Mol Cancer Res. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Mol Cancer Res. 2023 Sep 1; 21(9): 958–974. doi: 10.1158/1541-7786.MCR-23-0108
PMCID:
PMC10527559
AbstractArticlePDF–3.9M
7.
Some aspects of the life of SARS-CoV-2 ORF3a protein in mammalian cells
Song Jiao, Pablo Miranda, Yan Li, Dragan Maric, Miguel Holmgren
Heliyon. 2023 Aug; 9(8): e18754. Published online 2023 Aug 1. doi: 10.1016/j.heliyon.2023.e18754
PMCID:
PMC10440475
AbstractArticlePDF–8.9M
8.
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains
Julia Jülg, Dieter Edbauer, Christian Behrends
EMBO Rep. 2023 Aug; 24(8): e55895. Published online 2023 Jun 15. doi: 10.15252/embr.202255895
PMCID:
PMC10398660
AbstractArticlePDF–2.4M
9.
Protocadherin 20 maintains intestinal barrier function to protect against Crohn’s disease by targeting ATF6
Shanshan Huang, Zhuo Xie, Jing Han, Huiling Wang, Guang Yang, Manying Li, Gaoshi Zhou, Ying Wang, Lixuan Li, Li Li, Zhirong Zeng, Jun Yu, Minhu Chen, Shenghong Zhang
Genome Biol. 2023; 24: 159. Published online 2023 Jul 5. doi: 10.1186/s13059-023-02991-0
PMCID:
PMC10320870
AbstractArticlePDF–5.9M
10.
ERVW-1 Activates ATF6-Mediated Unfolded Protein Response by Decreasing GANAB in Recent-Onset Schizophrenia
Xing Xue, Xiulin Wu, Lijuan Liu, Lianzhong Liu, Fan Zhu
Viruses. 2023 Jun; 15(6): 1298. Published online 2023 May 31. doi: 10.3390/v15061298
PMCID:
PMC10304270
AbstractArticlePDF–6.3M
11.
Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice
Shengyu Jin, Byungseok Jin, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Sho Koyasu, Hiroshi Harada, Kazutoshi Mori
Mol Biol Cell. 2023 Mar 1; 34(3): ar20. Published online 2023 Feb 21. doi: 10.1091/mbc.E22-07-0292
PMCID:
PMC10011727
AbstractArticlePDF–11M
12.
ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer
Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brooke E. Sanders, Lily L. Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Miriam D. Post, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B. Chuong, Benjamin G. Bitler
Mol Cancer Res. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Mol Cancer Res. 2023 Jan 3; 21(1): 3–13. doi: 10.1158/1541-7786.MCR-22-0102
PMCID:
PMC9812934
AbstractArticlePDF–1.5M
13.
Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease
Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel
Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205
PMCID:
PMC9348576
AbstractArticlePDF–3.0M
14.
Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways
Ruohan Li, Huaixiang Zhou, Mingzhe Li, Qiuyan Mai, Zhang Fu, Youheng Jiang, Changxue Li, Yunfei Gao, Yunping Fan, Kaiming Wu, Clive Da Costa, Xia Sheng, Yulong He, Ningning Li
Cells. 2022 Jul; 11(14): 2136. Published online 2022 Jul 7. doi: 10.3390/cells11142136
PMCID:
PMC9324664
AbstractArticlePDF–14M
15.
ATF6α promotes prostate cancer progression by enhancing PLA2G4A‐mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis
Ru Zhao, Ye Lv, Tingting Feng, Ruojia Zhang, Luna Ge, Jihong Pan, Bo Han, Guanhua Song, Lin Wang
Prostate. 2022 Apr 1; 82(5): 617–629. Published online 2022 Jan 28. doi: 10.1002/pros.24308
PMCID:
PMC9303695
AbstractArticlePDF–2.4M
16.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
17.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
18.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
19.
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress
Mengtian Cui, Qingfang Zhao, Jing Wang, Yang Si, Shan Cheng, Wei Ding
J Virol. 2022 Feb; 96(3): e01103-21. Prepublished online 2021 Dec 1. Published online 2022 Feb 9. doi: 10.1128/JVI.01103-21
PMCID:
PMC8826799
AbstractArticlePDF–2.0M
20.
ATF6 is essential for human cone photoreceptor development
Heike Kroeger, Julia M. D. Grandjean, Wei-Chieh Jerry Chiang, Daphne D. Bindels, Rebecca Mastey, Jennifer Okalova, Amanda Nguyen, Evan T. Powers, Jeffery W. Kelly, Neil J. Grimsey, Michel Michaelides, Joseph Carroll, R. Luke Wiseman, Jonathan H. Lin
Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2103196118. Published online 2021 Sep 24. doi: 10.1073/pnas.2103196118
PMCID:
PMC8488632
AbstractArticlePDF–2.6M

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