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Select item 107988581.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001382.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105202603.

Two domains of Tim50 coordinate translocation of proteins across the two mitochondrial membranes

Marcel G Genge, Shalini Roy Chowdhury, Vít Dohnálek, Kaori Yunoki, Takashi Hirashima, Toshiya Endo, Pavel Doležal, Dejana Mokranjac

Life Sci Alliance. 2023 Dec; 6(12): e202302122. Published online 2023 Sep 25. doi: 10.26508/lsa.202302122

PMCID:: PMC10520260

Abstract Article PDF–3.1M

Select item 105113244.

Central role of Tim17 in mitochondrial presequence protein translocation

Laura F. Fielden, Jakob D. Busch, Sandra G. Merkt, Iniyan Ganesan, Conny Steiert, Hanna B. Hasselblatt, Jon V. Busto, Christophe Wirth, Nicole Zufall, Sibylle Jungbluth, Katja Noll, Julia M. Dung, Ludmila Butenko, Karina von der Malsburg, Hans-Georg Koch, Carola Hunte, Martin van der Laan, Nils Wiedemann

Nature. 2023; 621(7979): 627–634. Published online 2023 Aug 1. doi: 10.1038/s41586-023-06477-8

PMCID:: PMC10511324

Abstract Article PDF–27M

Select item 102086455.

Mitochondrial protein import clogging as a mechanism of disease

Liam P Coyne, Xiaowen Wang, Jiyao Song, Ebbing de Jong, Karin Schneider, Paul T Massa, Frank A Middleton, Thomas Becker, Xin Jie Chen

eLife. 2023; 12: e84330. Published online 2023 May 2. doi: 10.7554/eLife.84330

PMCID:: PMC10208645

Abstract Article PDF–12M

Select item 92559696.

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

Holly C Ford, William J Allen, Gonçalo C Pereira, Xia Liu, Mark Simon Dillingham, Ian Collinson

eLife. 2022; 11: e75426. Published online 2022 Jun 8. doi: 10.7554/eLife.75426

PMCID:: PMC9255969

Abstract Article PDF–5.8M

Select item 92098117.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 89264018.

Tom70-based transcriptional regulation of mitochondrial biogenesis and aging

Qingqing Liu, Catherine E Chang, Alexandra C Wooldredge, Benjamin Fong, Brian K Kennedy, Chuankai Zhou

eLife. 2022; 11: e75658. Published online 2022 Mar 2. doi: 10.7554/eLife.75658

PMCID:: PMC8926401

Abstract Article PDF–21M

Select item 84825129.

Aim32 is a dual-localized 2Fe-2S mitochondrial protein that functions in redox quality control

Danyun Zhang, Owen R. Dailey, Daniel J. Simon, Kamilah Roca-Datzer, Yasaman Jami-Alahmadi, Mikayla S. Hennen, James A. Wohlschlegel, Carla M. Koehler, Deepa V. Dabir

J Biol Chem. 2021 Oct; 297(4): 101135. Published online 2021 Aug 28. doi: 10.1016/j.jbc.2021.101135

PMCID:: PMC8482512

Abstract Article PDF–5.0M

Select item 848154210.

Mapping protein interactions in the active TOM-TIM23 supercomplex

Ridhima Gomkale, Andreas Linden, Piotr Neumann, Alexander Benjamin Schendzielorz, Stefan Stoldt, Olexandr Dybkov, Markus Kilisch, Christian Schulz, Luis Daniel Cruz-Zaragoza, Blanche Schwappach, Ralf Ficner, Stefan Jakobs, Henning Urlaub, Peter Rehling

Nat Commun. 2021; 12: 5715. Published online 2021 Sep 29. doi: 10.1038/s41467-021-26016-1

PMCID:: PMC8481542

Abstract Article PDF–9.2M

Select item 824942011.

Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide

Shu Zhou, Maosen Ruan, Yunyan Li, Jing Yang, Suwen Bai, Christian Richter, Harald Schwalbe, Can Xie, Bing Shen, Junfeng Wang

Cell Res. 2021 Jul; 31(7): 821–824. Published online 2020 Dec 14. doi: 10.1038/s41422-020-00452-y

PMCID:: PMC8249420

Article PDF–3.9M

Select item 772018312.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117

PMCID:: PMC7720183

Abstract Article PDF–2.3M

Select item 765801013.

Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae

Katharina Reglinski, Laura Steinfort-Effelsberg, Erdinc Sezgin, Christian Klose, Harald W. Platta, Wolfgang Girzalsky, Christian Eggeling, Ralf Erdmann

Front Cell Dev Biol. 2020; 8: 574363. Published online 2020 Oct 29. doi: 10.3389/fcell.2020.574363

PMCID:: PMC7658010

Abstract Article PDF–1.8M

Select item 735316414.

Mgr2 regulates mitochondrial preprotein import by associating with channel-forming Tim23 subunit

Srujan Kumar Matta, Abhishek Kumar, Patrick D’Silva

Mol Biol Cell. 2020 May 15; 31(11): 1112–1123. doi: 10.1091/mbc.E19-12-0677

PMCID:: PMC7353164

Abstract Article PDF–1.6M

Select item 637591715.

A mutagenesis analysis of Tim50, the major receptor of the TIM23 complex, identifies regions that affect its interaction with Tim23

Dana Dayan, May Bandel, Umut Günsel, Inbal Nussbaum, Gali Prag, Dejana Mokranjac, Walter Neupert, Abdussalam Azem

Sci Rep. 2019; 9: 2012. Published online 2019 Feb 14. doi: 10.1038/s41598-018-38353-1

PMCID:: PMC6375917

Abstract Article PDF–1.7M

Select item 634096416.

Deletion of Mgr2p Affects the Gating Behavior of the TIM23 Complex

Oygul Mirzalieva, Shinhye Jeon, Kevin Damri, Ruth Hartke, Layla Drwesh, Keren Demishtein-Zohary, Abdussalam Azem, Cory D. Dunn, Pablo M. Peixoto

Front Physiol. 2018; 9: 1960. Published online 2019 Jan 15. doi: 10.3389/fphys.2018.01960

PMCID:: PMC6340964

Abstract Article PDF–384K

Select item 628012417.

Recruitment of Cytosolic J-Proteins by TOM Receptors Promotes Mitochondrial Protein Biogenesis

Łukasz Opaliński, Jiyao Song, Chantal Priesnitz, Lena-Sophie Wenz, Silke Oeljeklaus, Bettina Warscheid, Nikolaus Pfanner, Thomas Becker

Cell Rep. 2018 Nov 20; 25(8): 2036–2043.e5. Published online 2018 Nov 20. doi: 10.1016/j.celrep.2018.10.083

PMCID:: PMC6280124

Abstract Article

Select item 621571318.

Systematic Analysis of Complex Genetic Interactions

Elena Kuzmin, Benjamin VanderSluis, Wen Wang, Guihong Tan, Raamesh Deshpande, Yiqun Chen, Matej Usaj, Attila Balint, Mojca Mattiazzi Usaj, Jolanda van Leeuwen, Elizabeth N. Koch, Carles Pons, Andrius J. Dagilis, Michael Pryszlak, Jason Zi Yang Wang, Julia Hanchard, Margot Riggi, Kaicong Xu, Hamed Heydari, Bryan-Joseph San Luis, Ermira Shuteriqi, Hongwei Zhu, Nydia Van Dyk, Sara Sharifpoor, Michael Costanzo, Robbie Loewith, Amy Caudy, Daniel Bolnick, Grant W. Brown, Brenda J. Andrews, Charles Boone, Chad L. Myers

Science. Author manuscript; available in PMC 2018 Nov 4.

Published in final edited form as: Science. 2018 Apr 20; 360(6386): eaao1729. doi: 10.1126/science.aao1729

PMCID:: PMC6215713

Abstract Article PDF–1.9M

Select item 616856419.

Motor recruitment to the TIM23 channel’s lateral gate restricts polypeptide release into the inner membrane

Alexander Benjamin Schendzielorz, Piotr Bragoszewski, Nataliia Naumenko, Ridhima Gomkale, Christian Schulz, Bernard Guiard, Agnieszka Chacinska, Peter Rehling

Nat Commun. 2018; 9: 4028. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06492-8

PMCID:: PMC6168564

Abstract Article PDF–1.4M

Select item 594595020.

Stendomycin selectively inhibits tIM23-dependent mitochondrial protein import

Ireos Filipuzzi, Janos Steffen, Mitchel Germain, Laetitia Goepfert, Michael A Conti, Christoph Potting, Raffaele Cerino, Martin Pfeifer, Philipp Krastel, Dominic Hoepfner, Julie Bastien, Carla M Koehler, Stephen B Helliwell

Nat Chem Biol. Author manuscript; available in PMC 2018 May 11.

Published in final edited form as: Nat Chem Biol. 2017 Dec; 13(12): 1239–1244. Published online 2017 Oct 9. doi: 10.1038/nchembio.2493

PMCID:: PMC5945950

Abstract Article PDF–664K

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