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Select item 113328441.

The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes

Amanda K. Riley, Michael Grant, Aidan Snell, Elizabeth Cromwell, Athea Vichas, Sitapriya Moorthi, Callie Rominger, Shrikar P. Modukuri, Anatoly Urisman, Pau Castel, Lixin Wan, Alice H. Berger

iScience. 2024 Aug 16; 27(8): 110499. Published online 2024 Jul 14. doi: 10.1016/j.isci.2024.110499

PMCID:: PMC11332844

Abstract Article PDF–3.6M

Select item 112267502.

Circ-USP9X accelerates deep vein thrombosis after fracture by acting as a miR-148b-3p sponge and upregulates SRC kinase signaling inhibitor 1

YongChao Wang, Qin Su, HaiRong Tang, Xin Lin, YanHua Yi, Qiang Tian, ZhangFeng Luo, MeiChun Fu, JiaQi Peng, KeYun Zhang

Clinics (Sao Paulo) 2024 Jan-Dec; 79: 100403. Published online 2024 Jun 14. doi: 10.1016/j.clinsp.2024.100403

PMCID:: PMC11226750

Abstract Article PDF–2.8M

Select item 103244173.

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model

Meng Ye, Yuanyuan Hu, Bowen Zhao, Qianxue Mou, Yueqi Ni, Jing Luo, Lu Li, Hong Zhang, Yin Zhao

Invest Ophthalmol Vis Sci. 2023 Jul; 64(10): 1. Published online 2023 Jul 3. doi: 10.1167/iovs.64.10.1

PMCID:: PMC10324417

Abstract Article PDF–5.1M

Select item 103078524.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 101575375.

USP9x promotes CD8 ⁺ T-cell dysfunction in association with autophagy inhibition in septic liver injury : USP9x inhibits CD8 ⁺ T cell autophagy in septic liver injury

Lulu Sheng, Juntao Chen, Yiqing Tong, Yi Zhang, Qiming Feng, Zhenghao Tang

Acta Biochim Biophys Sin (Shanghai) 2022 Dec; 54(12): 1765–1774. Published online 2022 Nov 16. doi: 10.3724/abbs.2022174

PMCID:: PMC10157537

Abstract Article PDF–1.9M

Select item 98491116.

USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells

Jinqiu Zhao, Jie Bai, Fengling Peng, Chan Qiu, Yongguo Li, Li Zhong

Cell Death Dis. 2023 Jan; 14(1): 40. Published online 2023 Jan 19. doi: 10.1038/s41419-022-05527-9

PMCID:: PMC9849111

Abstract Article PDF–4.2M

Select item 94819337.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 91063598.

Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis

Biqing Wang, Xuening Tang, Liu Yao, Yuxin Wang, Zhipeng Chen, Mengqi Li, Naishi Wu, Dawei Wu, Xiangchen Dai, Hongfeng Jiang, Ding Ai

J Clin Invest. 2022 May 16; 132(10): e154217. Published online 2022 May 16. doi: 10.1172/JCI154217

PMCID:: PMC9106359

Abstract Article PDF–16M

Select item 90626599.

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0

Fujun Hou, Zeyu Sun, Yue Deng, Siyu Chen, Xiyuan Yang, Feiyang Ji, Menghao Zhou, Keyi Ren, Dongli Pan

Front Microbiol. 2022; 13: 856471. Published online 2022 Apr 18. doi: 10.3389/fmicb.2022.856471

PMCID:: PMC9062659

Abstract Article PDF–3.5M

Select item 901455910.

Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat

Nature. Author manuscript; available in PMC 2022 Apr 18.

Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2

PMCID:: PMC9014559

Abstract Article PDF–6.6M

Select item 892084411.

Computationally predicted pathogenic USP9X mutation identified in infertile men does not affect spermatogenesis in mice

Wei Liu, Yue-Wen Wang, Huan Zhang, Xue-Feng Xie, Ao Ma, Qumar Zaman, Abdul Rafay Javed, Tanveer Abbas, Wasim Shah, Riaz Ahmad, Da-Ren Zhao, Hui Ma, Muhammad Zubair, Ranjha Khan, Qing-Hua Shi

Zool Res. 2022 Mar 18; 43(2): 225–228. doi: 10.24272/j.issn.2095-8137.2021.409

PMCID:: PMC8920844

Article PDF–3.9M

Select item 831323912.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 799455913.

The deubiquitinase Usp9x regulates PRC2-mediated chromatin reprogramming during mouse development

Trisha A. Macrae, Miguel Ramalho-Santos

Nat Commun. 2021; 12: 1865. Published online 2021 Mar 25. doi: 10.1038/s41467-021-21910-0

PMCID:: PMC7994559

Abstract Article PDF–2.6M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 773946615.

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis

Cristine R. Casingal, Takako Kikkawa, Hitoshi Inada, Yukio Sasaki, Noriko Osumi

Mol Brain. 2020; 13: 167. Published online 2020 Dec 16. doi: 10.1186/s13041-020-00706-1

PMCID:: PMC7739466

Abstract Article PDF–1.5M

Select item 729503316.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 700738617.

Usp9X Controls Ankyrin-repeat Domain Protein Homeostasis during Dendritic Spine Development

Sehyoun Yoon, Euan Parnell, Maria Kasherman, Marc P. Forrest, Kristoffer Myczek, Susitha Premarathne, Michelle C. Sanchez Vega, Michael Piper, Thomas H. J. Burne, Lachlan A. Jolly, Stephen A. Wood, Peter Penzes

Neuron. Author manuscript; available in PMC 2021 Feb 5.

Published in final edited form as: Neuron. 2020 Feb 5; 105(3): 506–521.e7. Published online 2019 Dec 5. doi: 10.1016/j.neuron.2019.11.003

PMCID:: PMC7007386

Abstract Article PDF–2.8M

Select item 669277018.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 645062719.

The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification

Mona Abed, Erik Verschueren, Hanna Budayeva, Peter Liu, Donald S. Kirkpatrick, Rohit Reja, Sarah K. Kummerfeld, Joshua D. Webster, Sarah Gierke, Mike Reichelt, Keith R. Anderson, Robert J. Newman, Merone Roose-Girma, Zora Modrusan, Hazal Pektas, Emin Maltepe, Kim Newton, Vishva M. Dixit

PLoS One. 2019; 14(4): e0214110. Published online 2019 Apr 5. doi: 10.1371/journal.pone.0214110

PMCID:: PMC6450627

Abstract Article PDF–2.8M

Select item 629804020.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

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