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Select item 116188201.

Downregulation of EZH2 inhibits epithelial–mesenchymal transition in enzalutamide-resistant prostate cancer

Zhuangzhuang Zhang, Xinyi Wang, Miyeong Kim, Daheng He, Chi Wang, Ka Wing Fong, Xiaoqi Liu

Prostate. Author manuscript; available in PMC 2024 Dec 5.

Published in final edited form as: Prostate. 2023 Nov; 83(15): 1458–1469. Published online 2023 Jul 20. doi: 10.1002/pros.24602

PMCID:: PMC11618820

Abstract Article PDF–1.0M

Select item 114657902.

Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2–MIR203A–SNAI2 axis

Dandan Zhang, Yumin Qiu, Wenming Zhang, Dongnian Du, Yang Liu, Lingpeng Liu, Jiajuan Li, Zehao Chen, Xuzhe Yu, Miao Ye, Wei Wang, Zijing Li, Jianghua Shao

J Transl Med. 2024; 22: 918. Published online 2024 Oct 10. doi: 10.1186/s12967-024-05690-x

PMCID:: PMC11465790

Abstract Article PDF–13M

Select item 114470503.

EZH2 specifically regulates ISL1 during embryonic urinary tract formation

Enrico Mingardo, Jeshurun C. Kalanithy, Gabriel Dworschak, Nina Ishorst, Öznur Yilmaz, Tobias Lindenberg, Ronja Hollstein, Tim Felger, Pierre-Olivier Angrand, Heiko Reutter, Benjamin Odermatt

Sci Rep. 2024; 14: 22909. Published online 2024 Oct 2. doi: 10.1038/s41598-024-74303-w

PMCID:: PMC11447050

Abstract Article PDF–2.5M

Select item 113766544.

EZH2 immunoexpression in pleomorphic adenoma and adenoid cystic carcinoma and clinicopathological features

Mariana Saturnino de NORONHA, Karolina Skarlet Silva VIANA, Maria Cássia Ferreira de AGUIAR, Cristiane Helena SQUARIZE, Mauro Henrique Nogueira Guimarães de ABREU, Elismauro Francisco MENDONÇA, Vanessa de Fátima BERNARDES

Braz Oral Res. 2024; 38: e018. Published online 2024 Mar 11. doi: 10.1590/1807-3107bor-2024.vol38.0018

PMCID:: PMC11376654

Abstract Article PDF–1.3M

Select item 113418235.

EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells

Amador Gallardo, Lourdes López-Onieva, Efres Belmonte-Reche, Iván Fernández-Rengel, Andrea Serrano-Prados, Aldara Molina, Antonio Sánchez-Pozo, David Landeira

Cell Death Dis. 2024 Aug; 15(8): 609. Published online 2024 Aug 22. doi: 10.1038/s41419-024-07011-y

PMCID:: PMC11341823

Abstract Article PDF–1.6M

Select item 113128036.

MTF2 facilitates the advancement of osteosarcoma through mediating EZH2/SFRP1/Wnt signaling

Xiaoming Hu, Yong Liu, Hongyu Shen, Ting Zhang, Tao Liang

J Orthop Surg Res. 2024; 19: 467. Published online 2024 Aug 8. doi: 10.1186/s13018-024-04965-9

PMCID:: PMC11312803

Abstract Article PDF–6.0M

Select item 112665907.

PRMT6 facilitates EZH2 protein stability by inhibiting TRAF6-mediated ubiquitination degradation to promote glioblastoma cell invasion and migration

Ji Wang, Shiquan Shen, Jian You, Zhaotao Wang, Yan Li, Yanming Chen, Yonghua Tuo, Danmin Chen, Haoming Yu, Jingbo Zhang, Fangran Wang, Xiao Pang, Zongyu Xiao, Qing Lan, Yezhong Wang

Cell Death Dis. 2024 Jul; 15(7): 524. Published online 2024 Jul 23. doi: 10.1038/s41419-024-06920-2

PMCID:: PMC11266590

Abstract Article PDF–6.5M

Select item 112524068.

NOP2 facilitates EZH2-mediated epithelial–mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression

Ying Yang, Hongzhao Fan, Hongyang Liu, Xueling Lou, Nan Xiao, Chenxing Zhang, Huanxiang Chen, Shuangshuang Chen, Huihui Gu, Hongchun Liu, Junhu Wan

Cell Death Dis. 2024 Jul; 15(7): 506. Published online 2024 Jul 16. doi: 10.1038/s41419-024-06899-w

PMCID:: PMC11252406

Abstract Article PDF–9.3M

Select item 112379309.

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein

Xiao Tang, Yang Liu, Jinhui Wang, Teng Long, Bobo Wing Yee Mok, Yan Huang, Ziqing Peng, Qinyu Jia, Chengxi Liu, Pui-Kin So, Sirius Pui-Kam Tse, Cheuk Hei NG, Shiyi Liu, Fei Sun, Shaojun Tang, Zhong-Ping Yao, Honglin Chen, Yusong Guo

J Biol Chem. 2024 Jun; 300(6): 107390. Published online 2024 May 21. doi: 10.1016/j.jbc.2024.107390

PMCID:: PMC11237930

Abstract Article PDF–3.8M

Select item 1116693610.

Enzyme-independent role of EZH2 in regulating cell cycle progression via the SKP2-KIP/CIP pathway

Tania Colon, Ziyue Kou, Byeong Hyeok Choi, Franklin Tran, Edwin Zheng, Wei Dai

Sci Rep. 2024; 14: 13389. Published online 2024 Jun 11. doi: 10.1038/s41598-024-64338-4

Correction in:: Sci Rep. 2024; 14: 17230.

PMCID:: PMC11166936

Abstract Article PDF–3.9M

Select item 1115960811.

Enhancer of zeste homolog 2 downregulates E‐cadherin by mediating histone H3 methylation in gastric cancer cells

Satoshi Fujii, Atsushi Ochiai

Cancer Sci. 2008 Apr; 99(4): 738–746. Published online 2008 Mar 28. doi: 10.1111/j.1349-7006.2008.00743.x

PMCID:: PMC11159608

Abstract Article PDF–1.8M

Select item 1115927812.

Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker

Masashi Takawa, Ken Masuda, Masaki Kunizaki, Yataro Daigo, Katsunori Takagi, Yukiko Iwai, Hyun‐Soo Cho, Gouji Toyokawa, Yuka Yamane, Kazuhiro Maejima, Helen I. Field, Takaaki Kobayashi, Takayuki Akasu, Masanori Sugiyama, Eijyu Tsuchiya, Yutaka Atomi, Bruce A. J. Ponder, Yusuke Nakamura, Ryuji Hamamoto

Cancer Sci. 2011 Jul; 102(7): 1298–1305. Published online 2011 May 26. doi: 10.1111/j.1349-7006.2011.01958.x

PMCID:: PMC11159278

Abstract Article PDF–563K

Select item 1104792013.

Morphological Changes Induced by TKS4 Deficiency Can Be Reversed by EZH2 Inhibition in Colorectal Carcinoma Cells

Mevan Jacksi, Eva Schad, Agnes Tantos

Biomolecules. 2024 Apr; 14(4): 445. Published online 2024 Apr 5. doi: 10.3390/biom14040445

PMCID:: PMC11047920

Abstract Article PDF–3.7M

Select item 1103740514.

MELK aggravates lung adenocarcinoma by regulating EZH2 ubiquitination and H3K27me3 histone methylation of LATS2

Hui Yu, Xianrong Xu, Lirong Zhu, Shengjie Chen, Jincheng He

J Cell Mol Med. 2024 Apr; 28(8): e18216. Published online 2024 Apr 23. doi: 10.1111/jcmm.18216

PMCID:: PMC11037405

Abstract Article PDF–12M

Select item 1098044415.

Role of EZH2 in adipogenesis and obesity: Current state of the art and implications – A review

Haixia Wang

Medicine (Baltimore) 2022 Sep 9; 101(36): e30344. Published online 2022 Sep 9. doi: 10.1097/MD.0000000000030344

PMCID:: PMC10980444

Abstract Article PDF–988K

Select item 1092496716.

MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2

Abarna Sinha, Abhisikta Ghosh, Arnab Ghosh, Sonia Mathai, Jaydip Bhaumik, Asima Mukhopadhyay, Arindam Maitra, Nidhan K. Biswas, Sharmila Sengupta

Clin Epigenetics. 2024; 16: 40. Published online 2024 Mar 10. doi: 10.1186/s13148-024-01651-9

PMCID:: PMC10924967

Abstract Article PDF–3.7M

Select item 1086348717.

EZH2 Inhibition Promotes Tumor Immunogenicity in Lung Squamous Cell Carcinomas

Tanner J. DuCote, Xiulong Song, Kassandra J. Naughton, Fan Chen, Daniel R. Plaugher, Avery R. Childress, Abigail R. Gellert, Erika M. Skaggs, Xufeng Qu, Jinze Liu, Jinpeng Liu, Fei Li, Kwok-Kin Wong, Christine F. Brainson

Cancer Res Commun. 2024 Feb; 4(2): 388–403. Published online 2024 Feb 13. doi: 10.1158/2767-9764.CRC-23-0399