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Items: 1 to 20 of 46

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
RREB1 regulates neuronal proteostasis and the microtubule network
Emily N. Griffin, Thomas Jucius, Su-Eon Sim, Belinda S. Harris, Sven Heinz, Susan L. Ackerman
Sci Adv. 2024 Jan 12; 10(2): eadh3929. Published online 2024 Jan 10. doi: 10.1126/sciadv.adh3929
PMCID:
PMC10780896
AbstractArticlePDF–4.8M
3.
Sustained depletion of FXIII-A by inducing acquired FXIII-B deficiency
Amy W. Strilchuk, Scott C. Meixner, Jerry Leung, Nooshin S. Safikhan, Jayesh A. Kulkarni, Hannah M. Russell, Roy van der Meel, Michael R. Sutherland, A. Phillip Owens, III, Joseph S. Palumbo, Edward M. Conway, Edward L.G. Pryzdial, Pieter R. Cullis, Christian J. Kastrup
Blood. 2020 Dec 17; 136(25): 2946–2954. Published online 2020 Dec 17. doi: 10.1182/blood.2020004976
PMCID:
PMC9710420
AbstractArticle
4.
Mast cell–derived factor XIIIA contributes to sexual dimorphic defense against group B streptococcal infections
Adrian M. Piliponsky, Kavita Sharma, Phoenicia Quach, Alyssa Brokaw, Shayla Nguyen, Austyn Orvis, Siddhartha S. Saha, Nyssa Becker Samanas, Ravin Seepersaud, Yu Ping Tang, Emily Mackey, Gauri Bhise, Claire Gendrin, Anna Furuta, Albert J. Seo, Eric Guga, Irina Miralda, Michelle Coleman, Erin L. Sweeney, Charlotte A. Bäuml, Diana Imhof, Jessica M. Snyder, Adam J. Moeser, Lakshmi Rajagopal
J Clin Invest. 2022 Oct 17; 132(20): e157999. Published online 2022 Oct 17. doi: 10.1172/JCI157999
PMCID:
PMC9566924
AbstractArticlePDF–16M
5.
Fibrin(ogen) engagement of S. aureus promotes the host antimicrobial response and suppression of microbe dissemination following peritoneal infection
Oscar Negrón, Woosuk S. Hur, Joni Prasad, David S. Paul, Sarah E. Rowe, Jay L. Degen, Sara R. Abrahams, Silvio Antoniak, Brian P. Conlon, Wolfgang Bergmeier, Magnus Hӧӧk, Matthew J. Flick
PLoS Pathog. 2022 Jan; 18(1): e1010227. Published online 2022 Jan 18. doi: 10.1371/journal.ppat.1010227
PMCID:
PMC8797238
AbstractArticlePDF–2.8M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi
Cédric Duval, Adomas Baranauskas, Tímea Feller, Majid Ali, Lih T. Cheah, Nadira Y. Yuldasheva, Stephen R. Baker, Helen R. McPherson, Zaher Raslan, Marc A. Bailey, Richard M. Cubbon, Simon D. Connell, Ramzi A. Ajjan, Helen Philippou, Khalid M. Naseem, Victoria C. Ridger, Robert A. S. Ariëns
Proc Natl Acad Sci U S A. 2021 Jul 6; 118(27): e2103226118. Published online 2021 Jun 28. doi: 10.1073/pnas.2103226118
PMCID:
PMC8271579
AbstractArticlePDF–2.1M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
A high-fat diet delays plasmin generation in a thrombomodulin-dependent manner in mice
Adam Miszta, Anna K. Kopec, Asmita Pant, Lori A. Holle, James R. Byrnes, Daniel A. Lawrence, Kirk C. Hansen, Matthew J. Flick, James P. Luyendyk, Bas de Laat, Alisa S. Wolberg
Blood. 2020 May 7; 135(19): 1704–1717. Prepublished online 2020 Feb 13. doi: 10.1182/blood.2019004267
PMCID:
PMC7205812
AbstractArticle
10.
Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency
Kathryn J. Griffin, Laura M. Newell, Kingsley R. Simpson, Cora M.L. Beckers, Mark J. Drinkhill, Kristina F. Standeven, Lih T. Cheah, Siiri E. Iismaa, Peter J. Grant, Christopher L. Jackson, Richard J. Pease
Atherosclerosis. 2020 Feb; 294: 1–9. doi: 10.1016/j.atherosclerosis.2019.12.013
PMCID:
PMC7024992
AbstractArticlePDF–1.1M
11.
Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling
Krishnakali Dasgupta, Jong Uk Chung, Kesava Asam, Juhee Jeong
Dev Biol. Author manuscript; available in PMC 2020 Nov 15.
Published in final edited form as: Dev Biol. 2019 Nov 15; 455(2): 434–448. Published online 2019 Jul 24. doi: 10.1016/j.ydbio.2019.07.015
PMCID:
PMC6842427
AbstractArticlePDF–6.1M
12.
Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation
Lakmali Munasinghage Silva, Andrew Gary Lum, Collin Tran, Molly W. Shaw, Zhen Gao, Matthew J. Flick, Niki M. Moutsopoulos, Thomas H. Bugge, Eric S. Mullins
Blood. 2019 Jul 18; 134(3): 291–303. Prepublished online 2019 May 17. doi: 10.1182/blood.2018874859
PMCID:
PMC6639982
AbstractArticle
13.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
14.
Thrombin promotes diet-induced obesity through fibrin-driven inflammation
Anna K. Kopec, Sara R. Abrahams, Sherry Thornton, Joseph S. Palumbo, Eric S. Mullins, Senad Divanovic, Hartmut Weiler, A. Phillip Owens, III, Nigel Mackman, Ashley Goss, Joanne van Ryn, James P. Luyendyk, Matthew J. Flick
J Clin Invest. 2017 Aug 1; 127(8): 3152–3166. Published online 2017 Jul 24. doi: 10.1172/JCI92744
PMCID:
PMC5531415
AbstractArticlePDF–2.6M
15.
Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A
Cora M.L. Beckers, Kingsley R. Simpson, Kathryn J. Griffin, Jane M. Brown, Lih T. Cheah, Kerrie A. Smith, Jean Vacher, Paul A. Cordell, Mark T. Kearney, Peter J. Grant, Richard J. Pease
Arterioscler Thromb Vasc Biol. 2017 Aug; 37(8): 1494–1502. Published online 2017 Jul 26. doi: 10.1161/ATVBAHA.117.309271
PMCID:
PMC5526434
AbstractArticlePDF–754K
16.
Transglutaminases factor XIII-A and TG2 regulate resorption, adipogenesis and plasma fibronectin homeostasis in bone and bone marrow
Aisha Mousa, Cui Cui, Aimei Song, Vamsee D Myneni, Huifang Sun, Jin Jin Li, Monzur Murshed, Gerry Melino, Mari T Kaartinen
Cell Death Differ. 2017 May; 24(5): 844–854. Published online 2017 Apr 7. doi: 10.1038/cdd.2017.21
PMCID:
PMC5423109
AbstractArticlePDF–1.9M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression
Alexandra Naba, Karl R. Clauser, D. R. Mani, Steven A. Carr, Richard O. Hynes
Sci Rep. 2017; 7: 40495. Published online 2017 Jan 10. doi: 10.1038/srep40495
PMCID:
PMC5223159
AbstractArticlePDF–2.3M
19.
Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation
Nicholas J. Shubin, Veronika A. Glukhova, Morgan Clauson, Phuong Truong, Magnus Abrink, Gunnar Pejler, Nathan J. White, Gail H. Deutsch, Stephen R. Reeves, Tomas Vaisar, Richard G. James, Adrian M. Piliponsky
J Allergy Clin Immunol. Author manuscript; available in PMC 2018 Jan 1.
Published in final edited form as: J Allergy Clin Immunol. 2017 Jan; 139(1): 323–334. Published online 2016 May 13. doi: 10.1016/j.jaci.2016.03.051
PMCID:
PMC5107356
AbstractArticlePDF–1.3M
20.
Factor XIII-A transglutaminase deficient mice show signs of metabolically healthy obesity on high fat diet
Vamsee D. Myneni, Aisha Mousa, Mari T. Kaartinen
Sci Rep. 2016; 6: 35574. Published online 2016 Oct 19. doi: 10.1038/srep35574
PMCID:
PMC5069677
AbstractArticlePDF–1.1M

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