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Items: 1 to 20 of 32

1.
AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction
Hanan Qasim, Mehrdad Rajaei, Ying Xu, Arfaxad Reyes-Alcaraz, Hala Y. Abdelnasser, M. David Stewart, Satadru K. Lahiri, Xander H.T. Wehrens, Bradley K. McConnell
Circ Res. 2024 Apr 12; 134(8): 1006–1022. Published online 2024 Mar 20. doi: 10.1161/CIRCRESAHA.123.323655
PMCID:
PMC11075752
AbstractArticlePDF–7.9M
2.
14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway
Soumita Mukherjee, Somesh Roy, Shruti Mukherjee, Amaravadhi Harikishore, Anirban Bhunia, Atin K. Mandal
J Biol Chem. 2024 Mar; 300(3): 105725. Published online 2024 Feb 6. doi: 10.1016/j.jbc.2024.105725
PMCID:
PMC10926215
AbstractArticlePDF–2.9M
3.
cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor
Federica Campolo, Chiara Capponi, Maria Grazia Tarsitano, Marta Tenuta, Carlotta Pozza, Daniele Gianfrilli, Fabio Magliocca, Mary A. Venneri, Elena Vicini, Andrea Lenzi, Andrea M. Isidori, Federica Barbagallo
Front Endocrinol (Lausanne) 2022; 13: 1010924. Published online 2022 Oct 7. doi: 10.3389/fendo.2022.1010924
PMCID:
PMC9585345
AbstractArticlePDF–6.6M
4.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
5.
A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins
Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux
Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611
PMCID:
PMC8951556
AbstractArticlePDF–4.4M
6.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
7.
Phosphodiesterase 8A to discriminate in blood samples depressed patients and suicide attempters from healthy controls based on A-to-I RNA editing modifications
Nicolas Salvetat, Fabrice Chimienti, Christopher Cayzac, Benjamin Dubuc, Francisco Checa-Robles, Pierrick Dupre, Sandie Mereuze, Vipul Patel, Catherine Genty, Jean-Philippe Lang, Jean-François Pujol, Philippe Courtet, Dinah Weissmann
Transl Psychiatry. 2021; 11: 255. Published online 2021 Apr 30. doi: 10.1038/s41398-021-01377-9
PMCID:
PMC8087806
AbstractArticlePDF–865K
8.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
9.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
10.
Brain region-specific alterations of RNA editing in PDE8A mRNA in suicide decedents
Fabrice Chimienti, Laurent Cavarec, Laurent Vincent, Nicolas Salvetat, Victoria Arango, Mark D. Underwood, J. John Mann, Jean-François Pujol, Dinah Weissmann
Transl Psychiatry. 2019; 9: 91. Published online 2019 Feb 15. doi: 10.1038/s41398-018-0331-3
Correction in:
Transl Psychiatry. 2019; 9: 112.
PMCID:
PMC6377659
AbstractArticlePDF–1.3M
11.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
12.
PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6
Timothy B. Johnstone, Kaitlyn H. Smith, Cynthia J. Koziol-White, Fengying Li, Austin G. Kazarian, Maia L. Corpuz, Maya Shumyatcher, Frederick J. Ehlert, Blanca E. Himes, Reynold A. Panettieri, Jr., Rennolds S. Ostrom
Am J Respir Cell Mol Biol. 2018 Apr; 58(4): 530–541. doi: 10.1165/rcmb.2017-0294OC
PMCID:
PMC5894499
AbstractArticlePDF–1.1M
13.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
AbstractArticlePDF–3.2M
14.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
15.
Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape
Joanne B. Cole, Mange Manyama, Emmanuel Kimwaga, Joshua Mathayo, Jacinda R. Larson, Denise K. Liberton, Ken Lukowiak, Tracey M. Ferrara, Sheri L. Riccardi, Mao Li, Washington Mio, Michaela Prochazkova, Trevor Williams, Hong Li, Kenneth L. Jones, Ophir D. Klein, Stephanie A. Santorico, Benedikt Hallgrimsson, Richard A. Spritz
PLoS Genet. 2016 Aug; 12(8): e1006174. Published online 2016 Aug 25. doi: 10.1371/journal.pgen.1006174
PMCID:
PMC4999243
AbstractArticlePDF–6.8M
16.
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms
Karsten Boldt, Jeroen van Reeuwijk, Qianhao Lu, Konstantinos Koutroumpas, Thanh-Minh T. Nguyen, Yves Texier, Sylvia E. C. van Beersum, Nicola Horn, Jason R. Willer, Dorus A. Mans, Gerard Dougherty, Ideke J. C. Lamers, Karlien L. M. Coene, Heleen H. Arts, Matthew J. Betts, Tina Beyer, Emine Bolat, Christian Johannes Gloeckner, Khatera Haidari, Lisette Hetterschijt, Daniela Iaconis, Dagan Jenkins, Franziska Klose, Barbara Knapp, Brooke Latour, Stef J. F. Letteboer, Carlo L. Marcelis, Dragana Mitic, Manuela Morleo, Machteld M. Oud, Moniek Riemersma, Susan Rix, Paulien A. Terhal, Grischa Toedt, Teunis J. P. van Dam, Erik de Vrieze, Yasmin Wissinger, Ka Man Wu, Gordana Apic, Philip L. Beales, Oliver E. Blacque, Toby J. Gibson, Martijn A. Huynen, Nicholas Katsanis, Hannie Kremer, Heymut Omran, Erwin van Wijk, Uwe Wolfrum, François Kepes, Erica E. Davis, Brunella Franco, Rachel H. Giles, Marius Ueffing, Robert B. Russell, Ronald Roepman, UK10K Rare Diseases Group
Nat Commun. 2016; 7: 11491. Published online 2016 May 13. doi: 10.1038/ncomms11491
PMCID:
PMC4869170
AbstractArticlePDF–2.0M
17.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
18.
Phosphodiesterase 8a Supports HIV-1 Replication in Macrophages at the Level of Reverse Transcription
Thijs Booiman, Viviana Cobos Jiménez, Karel A. van Dort, Angélique B. van 't Wout, Neeltje A. Kootstra
PLoS One. 2014; 9(10): e109673. Published online 2014 Oct 8. doi: 10.1371/journal.pone.0109673
PMCID:
PMC4190361
AbstractArticlePDF–854K
19.
Active Site Coupling in PDE:PKA Complexes Promotes Resetting of Mammalian cAMP Signaling
Srinath Krishnamurthy, Balakrishnan Shenbaga Moorthy, Lim Xin Xiang, Lim Xin Shan, Kavitha Bharatham, Nikhil Kumar Tulsian, Ivana Mihalek, Ganesh S. Anand
Biophys J. 2014 Sep 16; 107(6): 1426–1440. doi: 10.1016/j.bpj.2014.07.050
PMCID:
PMC4167538
AbstractArticlePDF–3.0M
20.
Genetic variants associated with disordered eating
Tracey D Wade, Scott Gordon, Sarah Medland, Cynthia M. Bulik, Andrew C Heath, Grant W Montgomery, Nicholas G Martin
Int J Eat Disord. Author manuscript; available in PMC 2014 Sep 1.
Published in final edited form as: Int J Eat Disord. 2013 Sep; 46(6): 594–608. Published online 2013 Apr 9. doi: 10.1002/eat.22133
PMCID:
PMC3775874
AbstractArticlePDF–2.1M

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