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Select item 92923591.

PKD1 alleviates oxidative stress‐inhibited osteogenesis of rat bone marrow‐derived mesenchymal stem cells through TAZ activation

Tongtong Chen, Hanqi Wang, Chaoyin Jiang, Yong Lu

J Cell Biochem. 2021 Nov; 122(11): 1715–1725. Published online 2021 Aug 18. doi: 10.1002/jcb.30124

PMCID:: PMC9292359

Abstract Article PDF–1.7M

Select item 67058122.

PKD1 Promotes Functional Synapse Formation Coordinated with N-Cadherin in Hippocampus

Cheng Cen, Li-Da Luo, Wen-Qi Li, Gang Li, Na-Xi Tian, Ge Zheng, Dong-Min Yin, Yimin Zou, Yun Wang

J Neurosci. 2018 Jan 3; 38(1): 183–199. doi: 10.1523/JNEUROSCI.1640-17.2017

PMCID:: PMC6705812

Abstract Article PDF–6.1M

Select item 54654803.

Protein kinase D1 (PKD1) phosphorylation on Ser²⁰³ by type I p21-activated kinase (PAK) regulates PKD1 localization

Jen-Kuan Chang, Yang Ni, Liang Han, James Sinnett-Smith, Rodrigo Jacamo, Osvaldo Rey, Steven H. Young, Enrique Rozengurt

J Biol Chem. 2017 Jun 9; 292(23): 9523–9539. Published online 2017 Apr 13. doi: 10.1074/jbc.M116.771394

PMCID:: PMC5465480

Abstract Article PDF–3.0M

Select item 53505164.

Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins

Hemant B. Badgandi, Sun-hee Hwang, Issei S. Shimada, Evan Loriot, Saikat Mukhopadhyay

J Cell Biol. 2017 Mar 6; 216(3): 743–760. doi: 10.1083/jcb.201607095

PMCID:: PMC5350516

Abstract Article PDF–3.1M

Select item 50051095.

Pkd1 regulates lymphatic vascular morphogenesis during development

Baptiste Coxam, Amélie Sabine, Neil I. Bower, Kelly A. Smith, Cathy Pichol-Thievend, Renae Skoczylas, Jonathan W. Astin, Emmanuelle Frampton, Muriel Jaquet, Philip S. Crosier, Robert G. Parton, Natasha L. Harvey, Tatiana V. Petrova, Stefan Schulte-Merker, Mathias Francois, Benjamin M. Hogan

Cell Rep. Author manuscript; available in PMC 2016 Aug 30.

Published in final edited form as: Cell Rep. 2014 May 8; 7(3): 623–633. Published online 2014 Apr 24. doi: 10.1016/j.celrep.2014.03.063

PMCID:: PMC5005109

Abstract Article PDF–2.2M

Select item 49252106.

The Polycystin complex mediates WNT/Ca²⁺ signaling

Seokho Kim, Hongguang Nie, Vasyl Nesin, Uyen Tran, Patricia Outeda, Chang-Xi Bai, Jacob Keeling, Dipak Maskey, Terry Watnick, Oliver Wessely, Leonidas Tsiokas

Nat Cell Biol. Author manuscript; available in PMC 2016 Nov 23.

Published in final edited form as: Nat Cell Biol. 2016 Jul; 18(7): 752–764. Published online 2016 May 23. doi: 10.1038/ncb3363

PMCID:: PMC4925210

Abstract Article PDF–1.8M

Select item 48241557.

Positive cross talk between protein kinase D and β-catenin in intestinal epithelial cells: impact on β-catenin nuclear localization and phosphorylation at Ser⁵⁵²

Jia Wang, Liang Han, James Sinnett-Smith, Li-Li Han, Jan V. Stevens, Nora Rozengurt, Steven H. Young, Enrique Rozengurt

Am J Physiol Cell Physiol. 2016 Apr 1; 310(7): C542–C557. Published online 2016 Jan 6. doi: 10.1152/ajpcell.00302.2015

PMCID:: PMC4824155

Abstract Article

Select item 46175408.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 44708549.

Polycystin-1 is a Cardiomyocyte Mechanosensor That Governs L-type Ca²⁺ Channel Protein Stability

Zully Pedrozo, Alfredo Criollo, Pavan K. Battiprolu, Cyndi R. Morales, Ariel Contreras, Carolina Fernández, Nan Jiang, Xiang Luo, Michael J. Caplan, Stefan Somlo, Beverly A. Rothermel, Thomas G. Gillette, Sergio Lavandero, Joseph A. Hill

Circulation. Author manuscript; available in PMC 2016 Jun 16.

Published in final edited form as: Circulation. 2015 Jun 16; 131(24): 2131–2142. Published online 2015 Apr 17. doi: 10.1161/CIRCULATIONAHA.114.013537

PMCID:: PMC4470854

Abstract Article PDF–1.0M

Select item 435613510.

Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy

Yuan Yan Sin, Tamara P Martin, Lauren Wills, Susan Currie, George S Baillie

Cell Commun Signal. 2015; 13: 16. Published online 2015 Mar 7. doi: 10.1186/s12964-015-0094-x

PMCID:: PMC4356135

Abstract Article PDF–3.7M

Select item 423728311.

Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism

Hyunho Kim, Hangxue Xu, Qin Yao, Weizhe Li, Qiong Huang, Patricia Outeda, Valeriu Cebotaru, Marco Chiaravalli, Alessandra Boletta, Klaus Piontek, Gregory G. Germino, Edward J. Weinman, Terry Watnick, Feng Qian

Nat Commun. 2014 Nov 18; 5: 5482. Published online 2014 Nov 18. doi: 10.1038/ncomms6482

PMCID:: PMC4237283

Abstract Article PDF–3.4M

Select item 416882812.

Bardet–Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein

Xuefeng Su, Kaitlin Driscoll, Gang Yao, Anas Raed, Maoqing Wu, Philip L. Beales, Jing Zhou

Hum Mol Genet. 2014 Oct 15; 23(20): 5441–5451. Published online 2014 Jun 16. doi: 10.1093/hmg/ddu267

PMCID:: PMC4168828

Abstract Article PDF–1.0M

Select item 398927213.

Protein Kinase D Interacts with Neuronal Nitric Oxide Synthase and Phosphorylates the Activatory Residue Serine¹⁴¹²

Lucía Sánchez-Ruiloba, Clara Aicart-Ramos, Lucía García-Guerra, Julia Pose-Utrilla, Ignacio Rodríguez-Crespo, Teresa Iglesias

PLoS One. 2014; 9(4): e95191. Published online 2014 Apr 16. doi: 10.1371/journal.pone.0095191

PMCID:: PMC3989272

Abstract Article PDF–1.2M

Select item 376781014.

PKD1 Mediates Negative Feedback of PI3K/Akt Activation in Response to G Protein-Coupled Receptors

Yang Ni, James Sinnett-Smith, Steven H. Young, Enrique Rozengurt

PLoS One. 2013; 8(9): e73149. Published online 2013 Sep 9. doi: 10.1371/journal.pone.0073149

Correction in:: PLoS One. 2014; 9(1): 10.1371/annotation/70d3c7b0-9718-4bb1-abed-d0defc3b7fc4.

PMCID:: PMC3767810

Abstract Article PDF–1.6M

Select item 354707515.

A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

Sorin V Fedeles, Xin Tian, Anna-Rachel Gallagher, Michihiro Mitobe, Saori Nishio, Seung Hun Lee, Yiqiang Cai, Lin Geng, Craig M Crews, Stefan Somlo

Nat Genet. Author manuscript; available in PMC 2013 Jan 16.

Published in final edited form as: Nat Genet. 2011 Jun 19; 43(7): 639–647. Published online 2011 Jun 19. doi: 10.1038/ng.860

PMCID:: PMC3547075

Abstract Article PDF–2.9M

Select item 351613116.

Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1

Rebecca L. Foy, Vipul C. Chitalia, Maria V. Panchenko, Liling Zeng, Delia Lopez, Jean W. Lee, Shaunak V. Rana, Alessandra Boletta, Feng Qian, Leonidas Tsiokas, Klaus B. Piontek, Gregory G. Germino, Mina I. Zhou, Herbert T. Cohen

Hum Mol Genet. 2012 Dec 15; 21(26): 5456–5471. Published online 2012 Sep 21. doi: 10.1093/hmg/dds391

PMCID:: PMC3516131

Abstract Article PDF–897K

Select item 348445617.

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity

Katharina Hopp, Christopher J. Ward, Cynthia J. Hommerding, Samih H. Nasr, Han-Fang Tuan, Vladimir G. Gainullin, Sandro Rossetti, Vicente E. Torres, Peter C. Harris

J Clin Invest. 2012 Nov 1; 122(11): 4257–4273. Published online 2012 Oct 15. doi: 10.1172/JCI64313

PMCID:: PMC3484456

Abstract Article PDF–6.5M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311137619.

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease

Priyanka Pandey, Shan Qin, Jacqueline Ho, Jing Zhou, Jordan A Kreidberg

BMC Syst Biol. 2011; 5: 56. Published online 2011 Apr 25. doi: 10.1186/1752-0509-5-56

PMCID:: PMC3111376

Abstract Article PDF–2.0M

Select item 307198220.

Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

Surya M. Nauli, Yoshifumi Kawanabe, John J. Kaminski, William J. Pearce, Donald E. Ingber, Jing Zhou

Circulation. Author manuscript; available in PMC 2011 Apr 7.

Published in final edited form as: Circulation. 2008 Mar 4; 117(9): 1161–1171. Published online 2008 Feb 19. doi: 10.1161/CIRCULATIONAHA.107.710111

PMCID:: PMC3071982

Abstract Article PDF–2.4M

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