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Select item 111065281.

Inability to rescue stalled ribosomes results in overactivation of the integrated stress response

Ankanahalli N. Nanjaraj Urs, Victor Lasehinde, Lucas Kim, Elesa McDonald, Liewei L. Yan, Hani S. Zaher

J Biol Chem. 2024 May; 300(5): 107290. Published online 2024 Apr 16. doi: 10.1016/j.jbc.2024.107290

PMCID:: PMC11106528

Abstract Article PDF–1.6M

Select item 110400052.

An evolutionarily conserved phosphoserine-arginine salt bridge in the interface between ribosomal proteins uS4 and uS5 regulates translational accuracy in Saccharomyces cerevisiae

Kartikeya Joshi, Brooke Luisi, Grant Wunderlin, Sima Saleh, Anna Lilly, Temiloluwa Okusolubo, Philip J Farabaugh

Nucleic Acids Res. 2024 Apr 24; 52(7): 3989–4001. Published online 2024 Feb 10. doi: 10.1093/nar/gkae053

PMCID:: PMC11040005

Abstract Article PDF–1.4M

Select item 108687273.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107988584.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107001385.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105211376.

Checkpoint kinase interaction with DNA polymerase alpha regulates replication progression during stress

Andreas Hadjicharalambous, Alex J. Whale, Geylani Can, J. Mark Skehel, Jonathan M. Houseley, Philip Zegerman

Version 1. Wellcome Open Res. 2023; 8: 327. Published online 2023 Jul 26. doi: 10.12688/wellcomeopenres.19617.1

PMCID:: PMC10521137

Abstract Article PDF–4.0M

Select item 102333687.

A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Nir Cohen, Naama Aviram, Maya Schuldiner

EMBO J. 2023 Jun; 42(11): e113385. Published online 2023 Apr 19. doi: 10.15252/embj.2022113385

PMCID:: PMC10233368

Abstract Article PDF–1.2M

Select item 97236198.

The nucleoplasmic phase of pre-40S formation prior to nuclear export

Jingdong Cheng, Benjamin Lau, Matthias Thoms, Michael Ameismeier, Otto Berninghausen, Ed Hurt, Roland Beckmann

Nucleic Acids Res. 2022 Nov 11; 50(20): 11924–11937. Published online 2022 Nov 2. doi: 10.1093/nar/gkac961

PMCID:: PMC9723619

Abstract Article PDF–11M

Select item 92098119.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916002110.

Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome

Yu Zhao, Jay Rai, Chong Xu, Huan He, Hong Li

Commun Biol. 2022; 5: 523. Published online 2022 Jun 1. doi: 10.1038/s42003-022-03500-y

PMCID:: PMC9160021

Abstract Article PDF–5.0M

Select item 900791711.

Identification of 14-3-3 Proteins, Polo kinase, and RNA-binding protein Pes4 as Key Regulators of Meiotic Commitment in Budding Yeast

Janardan N. Gavade, Chris M. Puccia, S. Grace Herod, Jonathan C. Trinidad, Luke E. Berchowitz, Soni Lacefield

Curr Biol. Author manuscript; available in PMC 2023 Apr 11.

Published in final edited form as: Curr Biol. 2022 Apr 11; 32(7): 1534–1547.e9. Published online 2022 Mar 2. doi: 10.1016/j.cub.2022.02.022

PMCID:: PMC9007917

Abstract Article PDF–2.2M

Select item 824200112.

Overlapping regions of Caf20 mediate its interactions with the mRNA-5′cap-binding protein eIF4E and with ribosomes

Ebelechukwu C. Nwokoye, Eiman AlNaseem, Robert A. Crawford, Lydia M. Castelli, Martin D. Jennings, Christopher J. Kershaw, Graham D. Pavitt

Sci Rep. 2021; 11: 13467. Published online 2021 Jun 29. doi: 10.1038/s41598-021-92931-4

PMCID:: PMC8242001

Abstract Article PDF–2.2M

Select item 786261113.

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast

Ying Zhang, Evelina De Laurentiis, Katherine E. Bohnsack, Mascha Wahlig, Namit Ranjan, Simon Gruseck, Philipp Hackert, Tina Wölfle, Marina V. Rodnina, Blanche Schwappach, Sabine Rospert

Nat Commun. 2021; 12: 782. Published online 2021 Feb 4. doi: 10.1038/s41467-021-20981-3

PMCID:: PMC7862611

Abstract Article PDF–2.8M

Select item 775804914.

Bud23 promotes the final disassembly of the small subunit Processome in Saccharomyces cerevisiae

Joshua J. Black, Richa Sardana, Ezzeddine W. Elmir, Arlen W. Johnson

PLoS Genet. 2020 Dec; 16(12): e1009215. Published online 2020 Dec 11. doi: 10.1371/journal.pgen.1009215

PMCID:: PMC7758049

Abstract Article PDF–4.9M

Select item 772018315.

Exo1 recruits Cdc5 polo kinase to MutLγ to ensure efficient meiotic crossover formation

Aurore Sanchez, Céline Adam, Felix Rauh, Yann Duroc, Lepakshi Ranjha, Bérangère Lombard, Xiaojing Mu, Mélody Wintrebert, Damarys Loew, Alba Guarné, Stefano Gnan, Chun-Long Chen, Scott Keeney, Petr Cejka, Raphaël Guérois, Franz Klein, Jean-Baptiste Charbonnier, Valérie Borde

Proc Natl Acad Sci U S A. 2020 Dec 1; 117(48): 30577–30588. Published online 2020 Nov 16. doi: 10.1073/pnas.2013012117

PMCID:: PMC7720183

Abstract Article PDF–2.3M

Select item 770806316.

The catalytic activity of the translation termination factor methyltransferase Mtq2-Trm112 complex is required for large ribosomal subunit biogenesis

Caroline Lacoux, Ludivine Wacheul, Kritika Saraf, Nicolas Pythoud, Emmeline Huvelle, Sabine Figaro, Marc Graille, Christine Carapito, Denis L J Lafontaine, Valérie Heurgué-Hamard

Nucleic Acids Res. 2020 Dec 2; 48(21): 12310–12325. Published online 2020 Nov 9. doi: 10.1093/nar/gkaa972

PMCID:: PMC7708063

Abstract Article PDF–4.8M

Select item 706357117.

Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects

Ramya Lakshminarayan, Ben P. Phillips, Imogen L. Binnian, Natalia Gomez-Navarro, Norberto Escudero-Urquijo, Alan J. Warren, Elizabeth A. Miller

Curr Biol. 2020 Mar 9; 30(5): 854–864.e5. doi: 10.1016/j.cub.2019.12.060

PMCID:: PMC7063571

Abstract Article

Select item 664889518.

Tsr4 and Nap1, two novel members of the ribosomal protein chaperOME

Ingrid Rössler, Julia Embacher, Benjamin Pillet, Guillaume Murat, Laura Liesinger, Jutta Hafner, Julia Judith Unterluggauer, Ruth Birner-Gruenberger, Dieter Kressler, Brigitte Pertschy

Nucleic Acids Res. 2019 Jul 26; 47(13): 6984–7002. Published online 2019 May 7. doi: 10.1093/nar/gkz317