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Select item 114236781.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 113624592.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 110241853.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108724774.

Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle

Michael J. O’Brien, Athar Ansari

Biochim Biophys Acta Proteins Proteom. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Biochim Biophys Acta Proteins Proteom. 2024 Jan 1; 1872(1): 140968. Published online 2023 Oct 19. doi: 10.1016/j.bbapap.2023.140968

PMCID:: PMC10872477

Abstract Article PDF–1.7M

Select item 107988585.

Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking

Lucas J. Marmorale, Huan Jin, Thomas G. Reidy, Brandon Palomino-Alonso, Christopher J. Zysnarski, Fatima Jordan-Javed, Sagar Lahiri, Mara C. Duncan

J Cell Biol. 2024 Mar 4; 223(3): e202309047. Published online 2024 Jan 19. doi: 10.1083/jcb.202309047

PMCID:: PMC10798858

Abstract Article PDF–6.4M

Select item 107618696.

Dynamic stability of Sgt2 enables selective and privileged client handover in a chaperone triad

Hyunju Cho, Yumeng Liu, SangYoon Chung, Sowmya Chandrasekar, Shimon Weiss, Shu-ou Shan

Nat Commun. 2024; 15: 134. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44260-5

PMCID:: PMC10761869

Abstract Article PDF–3.0M

Select item 107001387.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105147008.

Xrn1 biochemically associates with eisosome proteins after the post diauxic shift in yeast

Baptiste Courtin, Abdelkader Namane, Maite Gomard, Laura Meyer, Alain Jacquier, Micheline Fromont-Racine

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000926. Published online 2023 Sep 7. doi: 10.17912/micropub.biology.000926

PMCID:: PMC10514700

Abstract Article PDF–1.7M

Select item 102977009.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 1024781110.

The GET pathway is a major bottleneck for maintaining proteostasis in Saccharomyces cerevisiae

Rebecca Josefson, Navinder Kumar, Xinxin Hao, Beidong Liu, Thomas Nyström

Sci Rep. 2023; 13: 9285. Published online 2023 Jun 7. doi: 10.1038/s41598-023-35666-8

PMCID:: PMC10247811

Abstract Article PDF–8.1M

Select item 1006833611.

MitoStores: chaperone‐controlled protein granules store mitochondrial precursors in the cytosol

Lena Krämer, Niko Dalheimer, Markus Räschle, Zuzana Storchová, Jan Pielage, Felix Boos, Johannes M Herrmann

EMBO J. 2023 Apr; 42(7): e112309. Published online 2023 Jan 27. doi: 10.15252/embj.2022112309

PMCID:: PMC10068336

Abstract Article PDF–3.9M

Select item 920981112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 805419313.

J-domain proteins promote client relay from Hsp70 during tail-anchored membrane protein targeting

Hyunju Cho, Woo Jun Shim, Yumeng Liu, Shu-ou Shan

J Biol Chem. 2021 Jan-Jun; 296: 100546. Published online 2021 Mar 17. doi: 10.1016/j.jbc.2021.100546

PMCID:: PMC8054193

Abstract Article PDF–3.5M

Select item 801070614.

Molecular basis of tail-anchored integral membrane protein recognition by the cochaperone Sgt2

Ku-Feng Lin, Michelle Y. Fry, Shyam M. Saladi, William M. Clemons, Jr.

J Biol Chem. 2021 Jan-Jun; 296: 100441. Published online 2021 Feb 19. doi: 10.1016/j.jbc.2021.100441

PMCID:: PMC8010706

Abstract Article PDF–3.1M

Select item 786261115.

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast

Ying Zhang, Evelina De Laurentiis, Katherine E. Bohnsack, Mascha Wahlig, Namit Ranjan, Simon Gruseck, Philipp Hackert, Tina Wölfle, Marina V. Rodnina, Blanche Schwappach, Sabine Rospert

Nat Commun. 2021; 12: 782. Published online 2021 Feb 4. doi: 10.1038/s41467-021-20981-3

PMCID:: PMC7862611

Abstract Article PDF–2.8M

Select item 668908616.

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range

Hannah Girstmair, Franziska Tippel, Abraham Lopez, Katarzyna Tych, Frank Stein, Per Haberkant, Philipp Werner Norbert Schmid, Dominic Helm, Matthias Rief, Michael Sattler, Johannes Buchner

Nat Commun. 2019; 10: 3626. Published online 2019 Aug 9. doi: 10.1038/s41467-019-11518-w

PMCID:: PMC6689086

Abstract Article PDF–2.3M

Select item 658646217.

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins

Verena Dederer, Anton Khmelinskii, Anna Gesine Huhn, Voytek Okreglak, Michael Knop, Marius K Lemberg

eLife. 2019; 8: e45506. Published online 2019 Jun 7. doi: 10.7554/eLife.45506

PMCID:: PMC6586462

Abstract Article PDF–4.0M

Select item 646940418.

Identification and Functional Testing of Novel Interacting Protein Partners for the Stress Sensors Wsc1p and Mid2p of Saccharomyces cerevisiae

Ednalise Santiago-Cartagena, Sahily González-Crespo, Vladimir Vélez, Nelson Martínez, Jamie Snider, Matthew Jessulat, Hiroyuki Aoki, Zoran Minic, Pearl Akamine, Inoushka Mejías, Luis M. Pérez, Brian C. Rymond, Mohan Babu, Igor Stagljar, José R. Rodríguez-Medina

G3 (Bethesda) 2019 Apr; 9(4): 1085–1102. Published online 2019 Feb 7. doi: 10.1534/g3.118.200985

PMCID:: PMC6469404

Abstract Article PDF–1.8M

Select item 634107319.

The metacaspase Yca1 maintains proteostasis through multiple interactions with the ubiquitin system

Amit Shrestha, Steve Brunette, William Lloyd Stanford, Lynn Arthur Megeney

Cell Discov. 2019; 5: 6. Published online 2019 Jan 22. doi: 10.1038/s41421-018-0071-9

PMCID:: PMC6341073

Abstract Article PDF–1.7M

Select item 621627720.

A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export

Paula Oliete‐Calvo, Joan Serrano‐Quílez, Carme Nuño‐Cabanes, María E Pérez‐Martínez, Luis M Soares, Bernhard Dichtl, Stephen Buratowski, José E Pérez‐Ortín, Susana Rodríguez‐Navarro

EMBO Rep. 2018 Nov; 19(11): e45992. Published online 2018 Sep 24. doi: 10.15252/embr.201845992