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Items: 1 to 20 of 51

1.
Mechanism and Effect of HNF4α Decrease in a Rat Model of Cirrhosis and Liver Failure
Marta Melis, Rebecca Marino, Jianmin Tian, Carla Johnson, Rahil Sethi, Michael Oertel, Ira J. Fox, Joseph Locker
Cell Mol Gastroenterol Hepatol. 2024; 17(3): 453–479. Published online 2023 Nov 21. doi: 10.1016/j.jcmgh.2023.11.009
PMCID:
PMC10837635
AbstractArticlePDF–4.4M
2.
Targeted Activation of HNF4α by AMPK Inhibits Apoptosis and Ameliorates Neurological Injury Caused by Cardiac Arrest in Rats
Haohong Zhan, Qiang Zhang, Chenyu Zhang, Jingge Cheng, Yilin Yang, Cong Liu, Shuhao Li, Chuyue Wang, Junqin Yang, Hanmei Ge, Dawang Zhou, Bo Li, Hongyan Wei, Chunlin Hu
Neurochem Res. 2023; 48(10): 3129–3145. Published online 2023 Jun 20. doi: 10.1007/s11064-023-03957-1
PMCID:
PMC10471732
AbstractArticlePDF–11M
3.
hsa-miR-34a-5p Ameliorates Hepatic Ischemia/Reperfusion Injury Via Targeting HNF4α
Xiaoqiang Zheng, Gang Wang, Jiang Yuan, Nuoya Li, Biaolei Yan, Jinlong Yan, Yanling Sheng
Turk J Gastroenterol. 2022 Jul; 33(7): 596–605. Published online 2022 Jul 1. doi: 10.5152/tjg.2022.21169
PMCID:
PMC9404684
AbstractArticlePDF–4.1M
4.
Maternal Malnutrition Affects Hepatic Metabolism through Decreased Hepatic Taurine Levels and Changes in HNF4A Methylation
Ji Eun Du, Young Ah You, Eun Jin Kwon, Soo Min Kim, Jeongae Lee, Ki Hwan Han, Young Ju Kim
Int J Mol Sci. 2020 Dec; 21(23): 9060. Published online 2020 Nov 28. doi: 10.3390/ijms21239060
PMCID:
PMC7729756
AbstractArticlePDF–2.4M
5.
Genetic and Epigenetic Modification of Rat Liver Progenitor Cells via HNF4α Transduction and 5’ Azacytidine Treatment: An Integrated miRNA and mRNA Expression Profile Analysis
Jennifer Bolleyn, Matthias Rombaut, Nisha Nair, Steven Branson, Anja Heymans, Marinee Chuah, Thierry VandenDriessche, Vera Rogiers, Joery De Kock, Tamara Vanhaecke
Genes (Basel) 2020 May; 11(5): 486. Published online 2020 Apr 29. doi: 10.3390/genes11050486
PMCID:
PMC7291069
AbstractArticlePDF–2.2M
6.
HNF4A Regulates the Formation of Hepatic Progenitor Cells from Human iPSC-Derived Endoderm by Facilitating Efficient Recruitment of RNA Pol II
Ann DeLaForest, Francesca Di Furio, Ran Jing, Amy Ludwig-Kubinski, Kirk Twaroski, Amanda Urick, Kirthi Pulakanti, Sridhar Rao, Stephen A. Duncan
Genes (Basel) 2019 Jan; 10(1): 21. Published online 2018 Dec 28. doi: 10.3390/genes10010021
PMCID:
PMC6356828
AbstractArticlePDF–4.4M
7.
Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks
Meng Qu, Tomas Duffy, Tsuyoshi Hirota, Steve A. Kay
Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12305–E12312. Published online 2018 Dec 10. doi: 10.1073/pnas.1816411115
PMCID:
PMC6310821
AbstractArticlePDF–1.1M
8.
Small Heterodimer Partner Regulates Circadian Cytochromes p450 and Drug-Induced Hepatotoxicity
Tianpeng Zhang, Fangjun Yu, Lianxia Guo, Min Chen, Xue Yuan, Baojian Wu
Theranostics. 2018; 8(19): 5246–5258. Published online 2018 Oct 22. doi: 10.7150/thno.28676
PMCID:
PMC6276094
AbstractArticlePDF–1.7M
9.
Hepatocyte nuclear factors as possible C-reactive protein transcriptional inducer in the liver and white adipose tissue of rats with experimental chronic renal failure
Elzbieta Sucajtys-Szulc, Alicja Debska-Slizien, Boleslaw Rutkowski, Ryszard Milczarek, Iwona Pelikant-Malecka, Tomasz Sledzinski, Julian Swierczynski, Marek Szolkiewicz
Mol Cell Biochem. 2018; 446(1): 11–23. Published online 2018 Jan 12. doi: 10.1007/s11010-018-3268-1
PMCID:
PMC6096500
AbstractArticlePDF–1.1M
10.
Hepatocyte Nuclear Factor (HNF)‐4α Induces Expression of Endothelial Fas Ligand (FasL) to Prevent Cancer Cell Transmigration: A Novel Defense Mechanism of Endothelium against Cancer Metastasis
Makoto Osanai, Hideki Chiba, Takashi Kojima, Masato Fujibe, Kazuhide Kuwahara, Hiromichi Kimura, Masaaki Satoh, Norimasa Sawada
Jpn J Cancer Res. 2002 May; 93(5): 532–541. doi: 10.1111/j.1349-7006.2002.tb01288.x
PMCID:
PMC5927027
SummaryPDF–1.1M
11.
Integrated microarray analysis provided novel insights to the pathogenesis of glaucoma
Jinhui Wang, Daofei Qu, Jinghong An, Guoming Yuan, Yufu Liu
Mol Med Rep. 2017 Dec; 16(6): 8735–8746. Published online 2017 Oct 4. doi: 10.3892/mmr.2017.7711
PMCID:
PMC5779953
AbstractArticlePDF–3.0M
12.
Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation
Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Guangyong Sun, Aiting Yang, Dong Zhang, Jian Huang, Yameng Sun, Wenshan Zhao, Hong Ma, Jidong Jia, Hong You
Stem Cell Res Ther. 2017; 8: 183. Published online 2017 Aug 14. doi: 10.1186/s13287-017-0629-8
PMCID:
PMC5557474
AbstractArticlePDF–4.0M
13.
Liver-type fatty acid binding protein interacts with hepatocyte nuclear factor 4α
Avery L. McIntosh, Anca D. Petrescu, Heather A. Hostetler, Ann B. Kier, Friedhelm Schroeder
FEBS Lett. Author manuscript; available in PMC 2014 Nov 29.
Published in final edited form as: FEBS Lett. 2013 Nov 29; 587(23): 3787–3791. Published online 2013 Oct 15. doi: 10.1016/j.febslet.2013.09.043
PMCID:
PMC3889205
AbstractArticlePDF–1.2M
14.
Preservation of hepatocyte nuclear factor 4α contributes to the beneficial effect of dietary medium chain triglyceride on alcohol-induced hepatic lipid dyshomeostasis in rats
Qiong Li, Wei Zhong, Yunping Qiu, Xinqin Kang, Xiuhua Sun, Xiaobing Tan, Yantao Zhao, Xinguo Sun, Wei Jia, Zhanxiang Zhou
Alcohol Clin Exp Res. Author manuscript; available in PMC 2014 Apr 1.
Published in final edited form as: Alcohol Clin Exp Res. 2013 Apr; 37(4): 587–598. Published online 2012 Nov 5. doi: 10.1111/acer.12013
PMCID:
PMC3618617
AbstractArticlePDF–2.2M
15.
Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules
Andre J. Faure, Dominic Schmidt, Stephen Watt, Petra C. Schwalie, Michael D. Wilson, Huiling Xu, Robert G. Ramsay, Duncan T. Odom, Paul Flicek
Genome Res. 2012 Nov; 22(11): 2163–2175. doi: 10.1101/gr.136507.111
PMCID:
PMC3483546
AbstractArticlePDF–1.2M
16.
Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells
Yoshifumi Sato, Mitsutoki Hatta, Md. Fazlul Karim, Tomohiro Sawa, Fan-Yan Wei, Shoki Sato, Mark A. Magnuson, Frank J. Gonzalez, Kazuhito Tomizawa, Takaaki Akaike, Tatsuya Yoshizawa, Kazuya Yamagata
J Biol Chem. 2012 Jun 29; 287(27): 23236–23245. Published online 2012 May 15. doi: 10.1074/jbc.M112.368779
PMCID:
PMC3391104
AbstractArticlePDF–2.4M
17.
Activation of Bile Acid Biosynthesis by the p38 Mitogen-activated Protein Kinase (MAPK): HEPATOCYTE NUCLEAR FACTOR-4α PHOSPHORYLATION BY THE p38 MAPK IS REQUIRED FOR CHOLESTEROL 7α-HYDROXYLASE EXPRESSION
Zhumei Xu, Olga L. Tavares-Sanchez, Quanzhong Li, Josephine Fernando, Carmen M. Rodriguez, Elaine J. Studer, William M. Pandak, Phillip B. Hylemon, Gregorio Gil
J Biol Chem. Author manuscript; available in PMC 2012 Mar 2.
Published in final edited form as: J Biol Chem. 2007 Aug 24; 282(34): 24607–24614. Published online 2007 Jun 30. doi: 10.1074/jbc.M611481200
PMCID:
PMC3291957
AbstractArticlePDF–1.9M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets
Ionel Sandovici, Noel H. Smith, Marloes Dekker Nitert, Matthew Ackers-Johnson, Santiago Uribe-Lewis, Yoko Ito, R. Huw Jones, Victor E. Marquez, William Cairns, Mohammed Tadayyon, Laura P. O’Neill, Adele Murrell, Charlotte Ling, Miguel Constância, Susan E. Ozanne
Proc Natl Acad Sci U S A. 2011 Mar 29; 108(13): 5449–5454. Published online 2011 Mar 8. doi: 10.1073/pnas.1019007108
PMCID:
PMC3069181
AbstractArticlePDF–675K
20.
Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression
Zhongyan Wang, Peter A. Burke
FEBS J. Author manuscript; available in PMC 2011 Oct 1.
Published in final edited form as: FEBS J. 2010 Oct; 277(19): 4066–4075. Published online 2010 Aug 23. doi: 10.1111/j.1742-4658.2010.07802.x
PMCID:
PMC2939928
AbstractArticlePDF–1.4M

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