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Select item 111657141.

Emx2 lineage tracing reveals antecedent patterns of planar polarity in the mouse inner ear

Ellison J. Goodrich, Michael R. Deans

Development. 2024 May 15; 151(10): dev202425. Published online 2024 May 16. doi: 10.1242/dev.202425

PMCID:: PMC11165714

Abstract Article

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108583413.

Increased Type I and Decreased Type II Hair Cells after Deletion of Sox2 in the Developing Mouse Utricle

Jingrong Lu, Lingxiang Hu, Bin Ye, Haixia Hu, Yong Tao, Yilai Shu, Hao Chiang, Vikrant Borse, Mingliang Xiang, Hao Wu, Albert S. B. Edge, Fuxin Shi

Neuroscience. Author manuscript; available in PMC 2024 Feb 10.

Published in final edited form as: Neuroscience. 2019 Dec 1; 422: 146–160. Published online 2019 Oct 31. doi: 10.1016/j.neuroscience.2019.09.027

PMCID:: PMC10858341

Abstract Article PDF–3.4M

Select item 106219074.

Oncomodulin Regulates Spontaneous Calcium Signaling and Maturation of Afferent Innervation in Cochlear Outer Hair Cells

Yang Yang, Kaitlin Murtha, Leslie K. Climer, Federico Ceriani, Pierce Thompson, Aubrey J. Hornak, Walter Marcotti, Dwayne D. Simmons

J Physiol. Author manuscript; available in PMC 2023 Nov 2.

Published in final edited form as: J Physiol. 2023 Oct; 601(19): 4291–4308. Published online 2023 Aug 29. doi: 10.1113/JP284690

PMCID:: PMC10621907

Abstract Article PDF–3.1M

Select item 98033605.

Tbx2 is a master regulator of inner versus outer hair cell differentiation

Jaime García-Añoveros, John C. Clancy, Chuan Zhi Foo, Ignacio García-Gómez, Yingjie Zhou, Kazuaki Homma, Mary Ann Cheatham, Anne Duggan

Nature. Author manuscript; available in PMC 2022 Dec 30.

Published in final edited form as: Nature. 2022 May; 605(7909): 298–303. Published online 2022 May 4. doi: 10.1038/s41586-022-04668-3

PMCID:: PMC9803360

Abstract Article PDF–4.3M

Select item 93738276.

Nanogel-mediated delivery of oncomodulin secreted from regeneration-associated macrophages promotes sensory axon regeneration in the spinal cord

Min Jung Kwon, Yeojin Seo, Hana Cho, Hyung Soon Kim, Young Joo Oh, Simay Genişcan, Minjae Kim, Hee Hwan Park, Eun-Hye Joe, Myung-Hee Kwon, Han Chang Kang, Byung Gon Kim

Theranostics. 2022; 12(13): 5856–5876. Published online 2022 Aug 1. doi: 10.7150/thno.73386

PMCID:: PMC9373827

Abstract Article PDF–4.0M

Select item 92972957.

Oncomodulin (OCM) uniquely regulates calcium signaling in neonatal cochlear outer hair cells

Kaitlin E. Murtha, Yang Yang, Federico Ceriani, Jing-Yi Jeng, Leslie K. Climer, Forrest Jones, Jack Charles, Sai K. Devana, Aubrey J. Hornak, Walter Marcotti, Dwayne D. Simmons

Cell Calcium. 2022 Jul; 105: 102613. doi: 10.1016/j.ceca.2022.102613

PMCID:: PMC9297295

Abstract Article

Select item 88749528.

The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice

Jon P. Niemi, Talia DeFrancesco-Oranburg, Andrew Cox, Jane A. Lindborg, Franklin D. Echevarria, Jemima McCluskey, Dwayne D. Simmons, Richard E. Zigmond

eNeuro. 2022 Jan-Feb; 9(1): ENEURO.0477-21.2022. Prepublished online 2022 Feb 7. Published online 2022 Feb 23. doi: 10.1523/ENEURO.0477-21.2022

PMCID:: PMC8874952

Abstract Article PDF–4.6M

Select item 86348919.

Deletion of Oncomodulin Gives Rise to Early Progressive Cochlear Dysfunction in C57 and CBA Mice

Leslie K. Climer, Aubrey J. Hornak, Kaitlin Murtha, Yang Yang, Andrew M. Cox, Preston L. Simpson, Andy Le, Dwayne D. Simmons

Front Aging Neurosci. 2021; 13: 749729. Published online 2021 Nov 15. doi: 10.3389/fnagi.2021.749729

PMCID:: PMC8634891

Abstract Article PDF–3.5M

Select item 818971910.

Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

Brent A Wilkerson, Heather L Zebroski, Connor R Finkbeiner, Alex D Chitsazan, Kylie E Beach, Nilasha Sen, Renee C Zhang, Olivia Bermingham-McDonogh

eLife. 2021; 10: e60108. Published online 2021 May 18. doi: 10.7554/eLife.60108

PMCID:: PMC8189719

Abstract Article PDF–15M

Select item 768787011.

Fgf8 genetic labeling reveals the early specification of vestibular hair cell type in mouse utricle

Evan M. Ratzan, Anne M. Moon, Michael R. Deans

Development. 2020 Nov 15; 147(22): dev192849. Published online 2020 Nov 19. doi: 10.1242/dev.192849

PMCID:: PMC7687870

Abstract Article

Select item 765239512.

Inhibition of a transcriptional repressor rescues hearing in a splicing factor–deficient mouse

Yoko Nakano, Susan Wiechert, Bernd Fritzsch, Botond Bánfi

Life Sci Alliance. 2020 Dec; 3(12): e202000841. Published online 2020 Oct 21. doi: 10.26508/lsa.202000841

PMCID:: PMC7652395

Abstract Article PDF–3.4M

Select item 742083913.

Retinoic acid synthesis and autoregulation mediate zonal patterning of vestibular organs and inner ear morphogenesis

Kazuya Ono, Lisa L. Sandell, Paul A. Trainor, Doris K. Wu

Development. 2020 Aug 1; 147(15): dev192070. Published online 2020 Aug 7. doi: 10.1242/dev.192070

PMCID:: PMC7420839

Abstract Article

Select item 694036614.

Retinoic acid degradation shapes zonal development of vestibular organs and sensitivity to transient linear accelerations

Kazuya Ono, James Keller, Omar López Ramírez, Antonia González Garrido, Omid A. Zobeiri, Hui Ho Vanessa Chang, Sarath Vijayakumar, Andrianna Ayiotis, Gregg Duester, Charles C. Della Santina, Sherri M. Jones, Kathleen E. Cullen, Ruth Anne Eatock, Doris K. Wu

Nat Commun. 2020; 11: 63. Published online 2020 Jan 2. doi: 10.1038/s41467-019-13710-4

PMCID:: PMC6940366

Abstract Article PDF–4.2M

Select item 645951015.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 641576316.

Fbxo2^VHC mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination

Byron H. Hartman, Robert Böscke, Daniel C. Ellwanger, Sawa Keymeulen, Mirko Scheibinger, Stefan Heller

Dev Biol. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Dev Biol. 2018 Nov 1; 443(1): 64–77. Published online 2018 Sep 1. doi: 10.1016/j.ydbio.2018.08.013

PMCID:: PMC6415763

Abstract Article PDF–5.0M

Select item 627942317.

Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1

Teerawat Wiwatpanit, Sarah M. Lorenzen, Jorge A. Cantú, Chuan Zhi Foo, Ann K. Hogan, Freddie Márquez, John C. Clancy, Matthew J. Schipma, Mary Ann Cheatham, Anne Duggan, Jaime García-Añoveros

Nature. Author manuscript; available in PMC 2019 Apr 10.

Published in final edited form as: Nature. 2018 Nov; 563(7733): 691–695. Published online 2018 Oct 10. doi: 10.1038/s41586-018-0570-8

Correction in:: Nature. 2018 Dec 5

PMCID:: PMC6279423

Abstract Article PDF–5.9M

Select item 626286918.

Characterization of spatial and temporal development of Type I and Type II hair cells in the mouse utricle using new cell-type-specific markers

Stephen McInturff, Joseph C. Burns, Matthew W. Kelley

Biol Open. 2018 Nov 15; 7(11): bio038083. Published online 2018 Nov 15. doi: 10.1242/bio.038083

PMCID:: PMC6262869

Abstract Article PDF–7.2M

Select item 589963619.

Domineering Non-Autonomy in Vangl1;Vangl2 Double Mutants Demonstrates Intercellular PCP Signaling in the Vertebrate Inner Ear

Michelle L. Stoller, Orvelin Roman, Jr., Michael R. Deans

Dev Biol. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Dev Biol. 2018 May 1; 437(1): 17–26. Published online 2018 Mar 3. doi: 10.1016/j.ydbio.2018.02.021

PMCID:: PMC5899636

Abstract Article PDF–2.0M

Select item 538853820.

Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells

Tao Jiang, Katie Kindt, Doris K Wu

eLife. 2017; 6: e23661. Published online 2017 Mar 7. doi: 10.7554/eLife.23661

PMCID:: PMC5388538

Abstract Article PDF–22M

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