PMC Links for GEO Profiles (Select 5044857) - PMC

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90205174.

Structural and functional consequences of NEDD8 phosphorylation

Katrin Stuber, Tobias Schneider, Jill Werner, Michael Kovermann, Andreas Marx, Martin Scheffner

Nat Commun. 2021; 12: 5939. Published online 2021 Oct 12. doi: 10.1038/s41467-021-26189-9

PMCID:: PMC9020517

Abstract Article PDF–2.8M

Select item 84213665.

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

Chen Shen, Anmada Nayak, Leif R. Neitzel, Amber A. Adams, Maya Silver-Isenstadt, Leah M. Sawyer, Hassina Benchabane, Huilan Wang, Nawat Bunnag, Bin Li, Daniel T. Wynn, Fan Yang, Marta Garcia-Contreras, Charles H. Williams, Sivanesan Dakshanamurthy, Charles C. Hong, Nagi G. Ayad, Anthony J. Capobianco, Yashi Ahmed, Ethan Lee, David J. Robbins

Nat Commun. 2021; 12: 5263. Published online 2021 Sep 6. doi: 10.1038/s41467-021-25634-z

PMCID:: PMC8421366

Abstract Article PDF–3.4M

Select item 83310926.

Reconstitution of human CMG helicase ubiquitylation by CUL2^LRR1 and multiple E2 enzymes

Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P.M. Labib

Biochem J. 2021 Jul 30; 478(14): 2825–2842. Prepublished online 2021 Jun 29. Published online 2021 Jul 23. doi: 10.1042/BCJ20210315

PMCID:: PMC8331092

Abstract Article PDF–1.9M

Select item 81650307.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79511808.

LncRNA H19 Alleviates Muscular Dystrophy Through Stabilizing Dystrophin

Yaohua Zhang, Yajuan Li, Qingsong Hu, Yutao Xi, Zhen Xing, Zhao Zhang, Lisa Huang, Jianbo Wu, Ke Liang, Tina K. Nguyen, Sergey D. Egranov, Chengcao Sun, Zilong Zhao, David H. Hawke, Jin Li, Deqiang Sun, Jean J. Kim, Ping Zhang, Jie Cheng, Abid Farida, Mien-Chie Hung, Leng Han, Radbod Darabi, Chunru Lin, Liuqing Yang

Nat Cell Biol. Author manuscript; available in PMC 2021 Apr 26.

Published in final edited form as: Nat Cell Biol. 2020 Nov; 22(11): 1332–1345. Published online 2020 Oct 26. doi: 10.1038/s41556-020-00595-5

PMCID:: PMC7951180

Abstract Article PDF–6.7M

Select item 79045809.

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

Joanna Liwocha, David T. Krist, Gerbrand J. van der Heden van Noort, Fynn M. Hansen, Vinh H. Truong, Ozge Karayel, Nicholas Purser, Daniel Houston, Nicole Burton, Mark J. Bostock, Michael Sattler, Matthias Mann, Joseph S. Harrison, Gary Kleiger, Huib Ovaa, Brenda A. Schulman

Nat Chem Biol. Author manuscript; available in PMC 2021 Jun 7.

Published in final edited form as: Nat Chem Biol. 2021 Mar; 17(3): 272–279. Published online 2020 Dec 7. doi: 10.1038/s41589-020-00696-0

PMCID:: PMC7904580

Abstract Article PDF–3.0M

Select item 697592710.

Robust cullin-RING ligase function is established by a multiplicity of poly-ubiquitylation pathways

Spencer Hill, Kurt Reichermeier, Daniel C Scott, Lorena Samentar, Jasmin Coulombe-Huntington, Luisa Izzi, Xiaojing Tang, Rebeca Ibarra, Thierry Bertomeu, Annie Moradian, Michael J Sweredoski, Nora Caberoy, Brenda A Schulman, Frank Sicheri, Mike Tyers, Gary Kleiger

eLife. 2019; 8: e51163. Published online 2019 Dec 23. doi: 10.7554/eLife.51163

PMCID:: PMC6975927

Abstract Article PDF–4.5M

Select item 651759911.

GP78 Cooperates with Dual-Specificity Phosphatase 1 To Stimulate Epidermal Growth Factor Receptor-Mediated Extracellular Signal-Regulated Kinase Signaling

Dhong Hyo Kho, Mohammed Hafiz Uddin, Madhumita Chatterjee, Andreas Vogt, Avraham Raz, Gen Sheng Wu

Mol Cell Biol. 2019 Jun 1; 39(11): e00485-18. Prepublished online 2019 May 6. Published online 2019 May 14. doi: 10.1128/MCB.00485-18

PMCID:: PMC6517599

Abstract Article PDF–3.1M

Select item 625435012.

Crystal structure of a human ubiquitin E1–ubiquitin complex reveals conserved functional elements essential for activity

Zongyang Lv, Katelyn M. Williams, Lingmin Yuan, James H. Atkison, Shaun K. Olsen

J Biol Chem. 2018 Nov 23; 293(47): 18337–18352. Published online 2018 Oct 2. doi: 10.1074/jbc.RA118.003975

PMCID:: PMC6254350

Abstract Article PDF–6.9M

Select item 618510413.

UBE2G1 governs the destruction of cereblon neomorphic substrates

Gang Lu, Stephanie Weng, Mary Matyskiela, Xinde Zheng, Wei Fang, Scott Wood, Christine Surka, Reina Mizukoshi, Chin-Chun Lu, Derek Mendy, In Sock Jang, Kai Wang, Mathieu Marella, Suzana Couto, Brian Cathers, James Carmichael, Philip Chamberlain, Mark Rolfe

eLife. 2018; 7: e40958. Published online 2018 Sep 20. doi: 10.7554/eLife.40958

PMCID:: PMC6185104

Abstract Article PDF–5.4M

Select item 614844614.

Genome-wide screen identifies cullin-RING ligase machinery required for lenalidomide-dependent CRL4^CRBN activity

Quinlan L. Sievers, Jessica A. Gasser, Glenn S. Cowley, Eric S. Fischer, Benjamin L. Ebert

Blood. 2018 Sep 20; 132(12): 1293–1303. Prepublished online 2018 Jul 24. doi: 10.1182/blood-2018-01-821769

PMCID:: PMC6148446

Abstract Article

Select item 608604015.

Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay

Joanna Koszela, Nhan T. Pham, David Evans, Stefan Mann, Irene Perez-Pi, Steven Shave, Derek F. J. Ceccarelli, Frank Sicheri, Mike Tyers, Manfred Auer

BMC Biol. 2018; 16: 88. Published online 2018 Aug 10. doi: 10.1186/s12915-018-0554-z

PMCID:: PMC6086040

Abstract Article PDF–1.4M

Select item 580361716.

A muscle‐specific MuRF1‐E2 network requires stabilization of MuRF1‐E2 complexes by telethonin, a newly identified substrate

Cécile Polge, Stéphanie Cabantous, Christiane Deval, Agnès Claustre, Antoine Hauvette, Catherine Bouchenot, Julien Aniort, Daniel Béchet, Lydie Combaret, Didier Attaix, Daniel Taillandier

J Cachexia Sarcopenia Muscle. 2018 Feb; 9(1): 129–145. Published online 2017 Dec 22. doi: 10.1002/jcsm.12249

PMCID:: PMC5803617

Abstract Article PDF–822K

Select item 573529717.

Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics

Y Li, H Sun, C Zhang, J Liu, H Zhang, F Fan, R A Everley, X Ning, Y Sun, J Hu, J Liu, J Zhang, W Ye, X Qiu, S Dai, B Liu, H Xu, S Fu, S P Gygi, C Zhou

Oncogene. 2017 Dec 14; 36(50): 6839–6849. Published online 2017 Aug 28. doi: 10.1038/onc.2017.289

PMCID:: PMC5735297

Abstract Article PDF–1.3M

Select item 567858118.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 541804419.

RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling

Ryan J. Malonis, Wenxiang Fu, Mark J. Jelcic, Marae Thompson, Brian S. Canter, Mary Tsikitis, Francisco J. Esteva, Irma Sánchez

J Biol Chem. 2017 May 5; 292(18): 7435–7451. Published online 2017 Mar 14. doi: 10.1074/jbc.M117.783662

PMCID:: PMC5418044

Abstract Article PDF–2.7M

Select item 510887220.

A cascading activity-based probe sequentially targets E1–E2–E3 ubiquitin enzymes

Monique P.C. Mulder, Katharina Witting, Ilana Berlin, Jonathan N. Pruneda, Kuen-Phon Wu, Jer-Gung Chang, Remco Merkx, Johanna Bialas, Marcus Groettrup, Alfred C.O. Vertegaal, Brenda A. Schulman, David Komander, Jacques Neefjes, Farid El Oualid, Huib Ovaa

Nat Chem Biol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Nat Chem Biol. 2016 Jul; 12(7): 523–530. Published online 2016 May 16. doi: 10.1038/nchembio.2084

PMCID:: PMC5108872

Abstract Article PDF–2.4M

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