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Select item 111461101.

P2X4 and P2X6 receptors associate with VE-cadherin in human endothelial cells

R. Glass, A. Loesch, P. Bodin, G. Burnstock

Cell Mol Life Sci. 2002 May; 59(5): 870–881. Published online 2002 May 1. doi: 10.1007/s00018-002-8474-y

PMCID:: PMC11146110

Abstract Article PDF–459K

Select item 110911372.

P2X7R and P2X4R expression of mice submandibular gland in high-fat diet/streptozotocin-induced type 2 diabetes

Jiratchaya Srisutha, Ippei Watari, Masato Akakura, Minami Watanabe, Chidsanu Changsiripun, Takashi Ono

Sci Rep. 2024; 14: 10855. Published online 2024 May 13. doi: 10.1038/s41598-024-60519-3

PMCID:: PMC11091137

Abstract Article PDF–17M

Select item 104042153.

Expression in skin biopsies supports genetic evidence linking CAMKK2, P2X7R and P2X4R with HIV-associated sensory neuropathy

Jessica Gaff, Fitri Octaviana, Connie Jackaman, Peter Kamerman, John Papadimitriou, Silvia Lee, Jenjira Mountford, Patricia Price

J Neurovirol. 2023; 29(3): 241–251. Published online 2023 May 11. doi: 10.1007/s13365-023-01134-2

PMCID:: PMC10404215

Abstract Article PDF–1.7M

Select item 91753764.

Blocking P2X purinoceptor 4 signalling alleviates cigarette smoke induced pulmonary inflammation

Sven Schneider, Irmgard Merfort, Marco Idzko, Andreas Zech

Respir Res. 2022; 23: 148. Published online 2022 Jun 8. doi: 10.1186/s12931-022-02072-z

PMCID:: PMC9175376

Abstract Article PDF–1.2M

Select item 91604535.

Activation of P2X4 receptor exacerbates acute brain injury after intracerebral hemorrhage

Si‐Ting Wu, Jin‐Rui Han, Nan Yao, Yu‐Lin Li, Fang Zhang, Yao Shi, Fu‐Dong Shi, Zhi‐Guo Li

CNS Neurosci Ther. 2022 Jul; 28(7): 1008–1018. Published online 2022 Mar 30. doi: 10.1111/cns.13831

PMCID:: PMC9160453

Abstract Article PDF–4.2M

Select item 85086266.

P2X4 Receptors Mediate Ca²⁺ Release from Lysosomes in Response to Stimulation of P2X7 and H₁ Histamine Receptors

Sin-Lih Tan, Muruj Barri, Peace Atakpa-Adaji, Colin W. Taylor, Ewan St. John Smith, Ruth D. Murrell-Lagnado

Int J Mol Sci. 2021 Oct; 22(19): 10492. Published online 2021 Sep 28. doi: 10.3390/ijms221910492

PMCID:: PMC8508626

Abstract Article PDF–4.8M

Select item 83710027.

Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients

Wulf Palinski, Maria Monti, Rosa Camerlingo, Ilaria Iacobucci, Serena Bocella, Federica Pinto, Clara Iannuzzi, Gelsomina Mansueto, Sara Pignatiello, Flavio Fazioli, Michele Gallo, Laura Marra, Flora Cozzolino, Annarosaria De Chiara, Piero Pucci, Antonio Bilancio, Filomena de Nigris

Cell Death Dis. 2021 Sep; 12(9): 797. Published online 2021 Aug 17. doi: 10.1038/s41419-021-04069-w

PMCID:: PMC8371002

Abstract Article PDF–7.1M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 76139479.

Colon tumor cell death causes mTOR dependence by paracrine P2X₄ stimulation

Mark Schmitt, Fatih Ceteci, Jalaj Gupta, Marina Pesic, Tim W. Böttger, Adele M. Nicolas, Kilian B. Kennel, Esther Engel, Matthias Schewe, Asude Kirisozu, Valentina Petrocelli, Yasamin Dabiri, Julia Varga, Mallika Ramakrishnan, Madina Karimova, Andrea Ablasser, Toshiro Sato, Melek C. Arkan, Frederic J. de Sauvage, Florian R. Greten

Nature. Author manuscript; available in PMC 2023 Jun 8.

Published in final edited form as: Nature. 2022 Nov 16; 612(7939): 347–353. Published online 2022 Nov 16. doi: 10.1038/s41586-022-05426-1

PMCID:: PMC7613947

Abstract Article PDF–3.8M

Select item 755582510.

New Insights of the Zn(II)-Induced P2 × 4R Positive Allosteric Modulation: Role of Head Receptor Domain SS2/SS3, E160 and D170

Francisco Andrés Peralta, J. Pablo Huidobro-Toro

Int J Mol Sci. 2020 Sep; 21(18): 6940. Published online 2020 Sep 22. doi: 10.3390/ijms21186940

PMCID:: PMC7555825

Abstract Article PDF–2.1M

Select item 743275811.

Contribution of P2X4 Receptors to CNS Function and Pathophysiology

Alejandro Montilla, Gilda Paloma Mata, Carlos Matute, Maria Domercq

Int J Mol Sci. 2020 Aug; 21(15): 5562. Published online 2020 Aug 3. doi: 10.3390/ijms21155562

PMCID:: PMC7432758

Abstract Article PDF–624K

Select item 740434212.

Resolving the Ionotropic P2X4 Receptor Mystery Points towards a New Therapeutic Target for Cardiovascular Diseases

Bruno Bragança, Paulo Correia-de-Sá

Int J Mol Sci. 2020 Jul; 21(14): 5005. Published online 2020 Jul 15. doi: 10.3390/ijms21145005

PMCID:: PMC7404342

Abstract Article PDF–952K

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 688328614.

Inflammation-induced upregulation of P2X₄ expression augments mucin secretion in airway epithelia

Veronika E. Winkelmann, Kristin E. Thompson, Kathrin Neuland, Ana M. Jaramillo, Giorgio Fois, Hanna Schmidt, Oliver H. Wittekindt, Wei Han, Michael J. Tuvim, Burton F. Dickey, Paul Dietl, Manfred Frick

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1; 316(1): L58–L70. Published online 2018 Oct 25. doi: 10.1152/ajplung.00157.2018

PMCID:: PMC6883286

Abstract Article

Select item 673713315.

Role of purinergic receptors in hepatobiliary carcinoma in Pakistani population: an approach towards proinflammatory role of P2X4 and P2X7 receptors

Arun Asif, Madiha Khalid, Sobia Manzoor, Hassam Ahmad, Aman Ur Rehman

Purinergic Signal. 2019 Sep; 15(3): 367–374. Published online 2019 Aug 10. doi: 10.1007/s11302-019-09675-0

PMCID:: PMC6737133

Abstract Article PDF–1.1M

Select item 578482416.

ATP evokes Ca²⁺ responses and CXCL5 secretion via P2X₄ receptor activation in human monocyte-derived macrophages

Janice A. Layhadi, Jeremy Turner, David Crossman, Samuel J. Fountain

J Immunol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Immunol. 2018 Feb 1; 200(3): 1159–1168. Published online 2017 Dec 18. doi: 10.4049/jimmunol.1700965

PMCID:: PMC5784824

Abstract Article PDF–1.9M

Select item 571323117.

P2X4 Receptor-Dependent Ca²⁺ Influx in Model Human Monocytes and Macrophages

Janice A. Layhadi, Samuel J. Fountain

Int J Mol Sci. 2017 Nov; 18(11): 2261. Published online 2017 Oct 27. doi: 10.3390/ijms18112261

PMCID:: PMC5713231

Abstract Article PDF–5.5M

Select item 558314818.

Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation

Cláudia Caldeira, Carolina Cunha, Ana R. Vaz, Ana S. Falcão, Andreia Barateiro, Elsa Seixas, Adelaide Fernandes, Dora Brites

Front Aging Neurosci. 2017; 9: 277. Published online 2017 Aug 31. doi: 10.3389/fnagi.2017.00277

PMCID:: PMC5583148

Abstract Article PDF–2.8M

Select item 553161119.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 542914020.

Purinergic receptors P2RX4 and P2RX7 in familial multiple sclerosis

A Dessa Sadovnick, Ben J Gu, Anthony L Traboulsee, Cecily Q Bernales, Mary Encarnacion, Irene M Yee, Maria G Criscuoli, Xin Huang, Amber Ou, Carol J Milligan, Steven Petrou, James S Wiley, Carles Vilariño-Güell

Hum Mutat. Author manuscript; available in PMC 2017 Jun 1.

Published in final edited form as: Hum Mutat. 2017 Jun; 38(6): 736–744. Published online 2017 Apr 13. doi: 10.1002/humu.23218

PMCID:: PMC5429140

Abstract Article PDF–973K

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