PMC Links for GEO Profiles (Select 50920785) - PMC

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Items: 17

Select item 80983091.

An Isoform of Ataxin‐3 Accumulates in the Nucleus of Neuronal Cells in Affected Brain Regions of SCA3 Patients

Thorsten Schmidt, G. Bernhard Landwehrmeyer, Ina Schmitt, Yvon Trottier, Georg Auburger, Franco Laccone, Thomas Klockgether, Michael Völpel, Jörg T. Epplen, Ludger Schöls, Olaf Riess

Brain Pathol. 1998 Oct; 8(4): 669–679. Published online 2006 Apr 5. doi: 10.1111/j.1750-3639.1998.tb00193.x

PMCID:: PMC8098309

Summary PDF–192K

Select item 67294322.

Expression of a Poly-Glutamine-Ataxin-3 Transgene in Orexin Neurons Induces Narcolepsy–Cataplexy in the Rat

Carsten T. Beuckmann, Christopher M. Sinton, S. Clay Williams, James A. Richardson, Robert E. Hammer, Takeshi Sakurai, Masashi Yanagisawa

J Neurosci. 2004 May 5; 24(18): 4469–4477. doi: 10.1523/JNEUROSCI.5560-03.2004

PMCID:: PMC6729432

Abstract Article PDF–452K

Select item 66745353.

Ataxin-3 Represses Transcription via Chromatin Binding, Interaction with Histone Deacetylase 3, and Histone Deacetylation

Bernd O. Evert, Julieta Araujo, Ana M. Vieira-Saecker, Rob A. I. de Vos, Sigrid Harendza, Thomas Klockgether, Ullrich Wüllner

J Neurosci. 2006 Nov 1; 26(44): 11474–11486. doi: 10.1523/JNEUROSCI.2053-06.2006

PMCID:: PMC6674535

Abstract Article PDF–881K

Select item 66726144.

Nuclear Localization of Ataxin-3 Is Required for the Manifestation of Symptoms in SCA3: In Vivo Evidence

Ulrike Bichelmeier, Thorsten Schmidt, Jeannette Hübener, Jana Boy, Lukas Rüttiger, Karina Häbig, Sven Poths, Michael Bonin, Marlies Knipper, Werner J. Schmidt, Johannes Wilbertz, Hartwig Wolburg, Franco Laccone, Olaf Riess

J Neurosci. 2007 Jul 11; 27(28): 7418–7428. doi: 10.1523/JNEUROSCI.4540-06.2007

PMCID:: PMC6672614

Abstract Article PDF–661K

Select item 47547145.

Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models

Carlos A. Matos, Clévio Nóbrega, Susana R. Louros, Bruno Almeida, Elisabete Ferreiro, Jorge Valero, Luís Pereira de Almeida, Sandra Macedo-Ribeiro, Ana Luísa Carvalho

J Cell Biol. 2016 Feb 15; 212(4): 465–480. doi: 10.1083/jcb.201506025

PMCID:: PMC4754714

Abstract Article PDF–2.7M

Select item 44410566.

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

Thomas M. Durcan, Edward A. Fon

Genes Dev. 2015 May 15; 29(10): 989–999. doi: 10.1101/gad.262758.115

PMCID:: PMC4441056

Abstract Article PDF–341K

Select item 42624947.

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells

Andreia Neves-Carvalho, Elsa Logarinho, Ana Freitas, Sara Duarte-Silva, Maria do Carmo Costa, Anabela Silva-Fernandes, Margarida Martins, Sofia Cravino Serra, André T. Lopes, Henry L. Paulson, Peter Heutink, João B. Relvas, Patrícia Maciel

Hum Mol Genet. 2015 Jan 1; 24(1): 100–117. Published online 2014 Aug 20. doi: 10.1093/hmg/ddu422

PMCID:: PMC4262494

Abstract Article PDF–1.7M

Select item 38269928.

A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates

Kaleena M. Bernardi, Jeffrey M. Williams, Takamasa Inoue, Aric Schultz, Billy Tsai

Mol Biol Cell. 2013 Nov 15; 24(22): 3545–3556. doi: 10.1091/mbc.E13-06-0332

PMCID:: PMC3826992

Abstract Article PDF–2.2M

Select item 38075299.

Ataxin-3 Is a Multivalent Ligand for the Parkin Ubl Domain

Jane J. Bai, Susan S. Safadi, Pascal Mercier, Kathryn R. Barber, Gary S. Shaw

Biochemistry. 2013 Oct 22; 52(42): 7369–7376. Published online 2013 Sep 24. doi: 10.1021/bi400780v

PMCID:: PMC3807529

Abstract Article PDF–2.9M

Select item 343531810.

Valosin-Containing Protein (VCP/p97) Is an Activator of Wild-Type Ataxin-3

Mário N. Laço, Luisa Cortes, Sue M. Travis, Henry L. Paulson, A. Cristina Rego

PLoS One. 2012; 7(9): e43563. Published online 2012 Sep 6. doi: 10.1371/journal.pone.0043563

PMCID:: PMC3435318

Abstract Article PDF–1.9M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316662012.

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

K. Matthew Scaglione, Eszter Zavodszky, Sokol V. Todi, Srikanth Patury, Ping Xu, Edgardo Rodríguez-Lebrón, Svetlana Fischer, John Konen, Ana Djarmati, Junmin Peng, Jason E. Gestwicki, Henry L. Paulson

Mol Cell. Author manuscript; available in PMC 2012 Aug 19.

Published in final edited form as: Mol Cell. 2011 Aug 19; 43(4): 599–612. doi: 10.1016/j.molcel.2011.05.036

PMCID:: PMC3166620

Abstract Article PDF–4.8M

Select item 300590613.

Most genome-wide significant susceptibility loci for schizophrenia and bipolar disorder reported to date cross-traditional diagnostic boundaries

Hywel J. Williams, Nicholas Craddock, Giancarlo Russo, Marian L. Hamshere, Valentina Moskvina, Sarah Dwyer, Rhodri L. Smith, Elaine Green, Detelina Grozeva, Peter Holmans, Michael J. Owen, Michael C. O'Donovan

Hum Mol Genet. 2011 Jan 15; 20(2): 387–391. Published online 2010 Oct 29. doi: 10.1093/hmg/ddq471

PMCID:: PMC3005906

Abstract Article PDF–94K

Select item 279688914.

Proteotoxic stress increases nuclear localization of ataxin-3

Christopher P. Reina, Xiaoyan Zhong, Randall N. Pittman

Hum Mol Genet. 2010 Jan 15; 19(2): 235–249. Published online 2009 Oct 19. doi: 10.1093/hmg/ddp482

PMCID:: PMC2796889

Abstract Article PDF–590K

Select item 255319915.

Allele-Specific RNA Silencing of Mutant Ataxin-3 Mediates Neuroprotection in a Rat Model of Machado-Joseph Disease

Sandro Alves, Isabel Nascimento-Ferreira, Gwennaëlle Auregan, Raymonde Hassig, Noëlle Dufour, Emmanuel Brouillet, Maria C. Pedroso de Lima, Philippe Hantraye, Luís Pereira de Almeida, Nicole Déglon

PLoS One. 2008; 3(10): e3341. Published online 2008 Oct 8. doi: 10.1371/journal.pone.0003341

PMCID:: PMC2553199

Abstract Article PDF–1.2M

Select item 206438816.

Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3

Qiuyan Wang, Lianyun Li, Yihong Ye

J Cell Biol. 2006 Sep 25; 174(7): 963–971. doi: 10.1083/jcb.200605100

PMCID:: PMC2064388

Abstract Article PDF–1.2M

Select item 144031217.

An arginine/lysine-rich motif is crucial for VCP/p97-mediated modulation of ataxin-3 fibrillogenesis

Annett Boeddrich, Sébastien Gaumer, Annette Haacke, Nikolay Tzvetkov, Mario Albrecht, Bernd O Evert, Eva C Müller, Rudi Lurz, Peter Breuer, Nancy Schugardt, Stephanie Plaßmann, Kexiang Xu, John M Warrick, Jaana Suopanki, Ullrich Wüllner, Ronald Frank, Ulrich F Hartl, Nancy M Bonini, Erich E Wanker

EMBO J. 2006 Apr 5; 25(7): 1547–1558. Published online 2006 Mar 9. doi: 10.1038/sj.emboj.7601043