PMC Links for GEO Profiles (Select 51037572) - PMC

Select item 78802251.

Explaining Divergent Observations Regarding Osteocalcin/GPRC6A Endocrine Signaling

Min Pi, Satoru Kenneth Nishimoto, L Darryl Quarles

Endocrinology. 2021 Apr; 162(4): bqab011. Published online 2021 Jan 20. doi: 10.1210/endocr/bqab011

PMCID:: PMC7880225

Abstract Article

Select item 73418782.

Humanized GPRC6A^KGKY is a gain-of-function polymorphism in mice

Min Pi, Fuyi Xu, Ruisong Ye, Satoru K. Nishimoto, Robert A. Kesterson, Robert W. Williams, Lu Lu, L. Darryl Quarles

Sci Rep. 2020; 10: 11143. Published online 2020 Jul 7. doi: 10.1038/s41598-020-68113-z

PMCID:: PMC7341878

Abstract Article PDF–1.8M

Select item 69234523.

SHBG141–161 Domain-Peptide Stimulates GPRC6A-Mediated Response in Leydig and β-Langerhans cell lines

Luca De Toni, Diego Guidolin, Vincenzo De Filippis, Daniele Peterle, Maria Santa Rocca, Andrea Di Nisio, Maurizio De Rocco Ponce, Carlo Foresta

Sci Rep. 2019; 9: 19432. Published online 2019 Dec 19. doi: 10.1038/s41598-019-55941-x

PMCID:: PMC6923452

Abstract Article PDF–1.9M

Select item 64743244.

Human GPRC6A Mediates Testosterone-Induced Mitogen-Activated Protein Kinases and mTORC1 Signaling in Prostate Cancer Cells

Ruisong Ye, Min Pi, Mohammed M. Nooh, Suleiman W. Bahout, L. Darryl Quarles

Mol Pharmacol. 2019 May; 95(5): 563–572. Published online 2019 May. doi: 10.1124/mol.118.115014

PMCID:: PMC6474324

Abstract Article PDF–1.0M

Select item 54900905.

CRISPR/Cas9 targeting of GPRC6A suppresses prostate cancer tumorigenesis in a human xenograft model

Ruisong Ye, Min Pi, John V. Cox, Satoru K. Nishimoto, L. Darryl Quarles

J Exp Clin Cancer Res. 2017; 36: 90. Published online 2017 Jun 28. doi: 10.1186/s13046-017-0561-x

PMCID:: PMC5490090

Abstract Article PDF–5.9M

Select item 52799366.

GPRC6A: Jack of all metabolism (or master of none)

Min Pi, Satoru Kenneth Nishimoto, L. Darryl Quarles

Mol Metab. 2017 Feb; 6(2): 185–193. Published online 2016 Dec 21. doi: 10.1016/j.molmet.2016.12.006

PMCID:: PMC5279936

Abstract Article PDF–1.7M

Select item 52704927.

Genetic Variations in the Human G Protein-coupled Receptor Class C, Group 6, Member A (GPRC6A) Control Cell Surface Expression and Function

Stine Jørgensen, Christian Theil Have, Christina Rye Underwood, Lars Dan Johansen, Petrine Wellendorph, Anette Prior Gjesing, Christinna V. Jørgensen, Shi Quan, Gao Rui, Asuka Inoue, Allan Linneberg, Niels Grarup, Wang Jun, Oluf Pedersen, Torben Hansen, Hans Bräuner-Osborne

J Biol Chem. 2017 Jan 27; 292(4): 1524–1534. Published online 2016 Dec 16. doi: 10.1074/jbc.M116.756577

PMCID:: PMC5270492

Abstract Article PDF–1.5M

Select item 42002448.

Testosterone Stimulates Duox1 Activity through GPRC6A in Skin Keratinocytes

Eunbi Ko, Hyun Choi, Borim Kim, Minsun Kim, Kkot-Nara Park, Il-Hong Bae, Young Kwan Sung, Tae Ryong Lee, Dong Wook Shin, Yun Soo Bae

J Biol Chem. 2014 Oct 17; 289(42): 28835–28845. Published online 2014 Aug 27. doi: 10.1074/jbc.M114.583450

PMCID:: PMC4200244

Abstract Article PDF–1.4M

Select item 39612839.

L-Arginine Stimulates Fibroblast Proliferation through the GPRC6A-ERK1/2 and PI3K/Akt Pathway

Takashi Fujiwara, Shigeyuki Kanazawa, Ryoko Ichibori, Tomoko Tanigawa, Takuya Magome, Kenta Shingaki, Shingo Miyata, Masaya Tohyama, Ko Hosokawa

PLoS One. 2014; 9(3): e92168. Published online 2014 Mar 20. doi: 10.1371/journal.pone.0092168

PMCID:: PMC3961283

Abstract Article PDF–4.0M

Select item 366881310.

Osteocalcin regulates murine and human fertility through a pancreas-bone-testis axis

Franck Oury, Mathieu Ferron, Wang Huizhen, Cyrille Confavreux, Lin Xu, Julie Lacombe, Prashanth Srinivas, Alexandre Chamouni, Francesca Lugani, Herve Lejeune, T. Rajendra Kumar, Ingrid Plotton, Gerard Karsenty

J Clin Invest. 2013 Jun 3; 123(6): 2421–2433. Published online 2013 May 24. doi: 10.1172/JCI65952

Correction in:: J Clin Invest. 2014 Dec 1; 124(12): 5522.

Correction in:: J Clin Invest. 2015 May 1; 125(5): 2180.

PMCID:: PMC3668813

Abstract Article PDF–4.9M

Select item 357605811.

The G Protein-coupled Receptor Family C Group 6 Subtype A (GPRC6A) Receptor Is Involved in Amino Acid-induced Glucagon-like Peptide-1 Secretion from GLUTag Cells

Manami Oya, Tetsuya Kitaguchi, Ramona Pais, Frank Reimann, Fiona Gribble, Takashi Tsuboi

J Biol Chem. 2013 Feb 15; 288(7): 4513–4521. Published online 2012 Dec 26. doi: 10.1074/jbc.M112.402677

PMCID:: PMC3576058

Abstract Article PDF–2.1M

Select item 353542212.

Extracellular Ca²⁺ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors

Manuela Rossol, Matthias Pierer, Nora Raulien, Dagmar Quandt, Undine Meusch, Kathrin Rothe, Kristin Schubert, Torsten Schöneberg, Michael Schaefer, Ute Krügel, Sanela Smajilovic, Hans Bräuner-Osborne, Christoph Baerwald, Ulf Wagner

Nat Commun. 2012 Dec 27; 3: 1329. Published online 2012 Dec 27. doi: 10.1038/ncomms2339

PMCID:: PMC3535422

Abstract Article PDF–635K

Select item 336066213.

Replication and Fine Mapping for Association of the C2orf43, FOXP4, GPRC6A and RFX6 Genes with Prostate Cancer in the Chinese Population

Qing-Zhi Long, Yue-Feng Du, Xiao-Ying Ding, Xiang Li, Wen-Bin Song, Yong Yang, Peng Zhang, Jian-Ping Zhou, Xiao-Gang Liu

PLoS One. 2012; 7(5): e37866. Published online 2012 May 25. doi: 10.1371/journal.pone.0037866

PMCID:: PMC3360662

Abstract Article PDF–1.3M

Select item 318329114.

GPRC6A regulates prostate cancer progression

Min Pi, L. Darryl Quarles

Prostate. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Prostate. 2012 Mar; 72(4): 399–409. Published online 2011 Jun 16. doi: 10.1002/pros.21442

PMCID:: PMC3183291

Abstract Article PDF–1.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315336916.

Impaired Osteoblast Function in GPRC6A Null Mice

Min Pi, Lishu Zhang, Shu-Feng Lei, Min-Zhao Huang, Wenyu Zhu, Jianghong Zhang, Hui Shen, Hong-Wen Deng, L Darryl Quarles

J Bone Miner Res. 2010 May; 25(5): 1092–1102. Published online 2009 Oct 26. doi: 10.1359/jbmr.091037

PMCID:: PMC3153369

Abstract Article PDF–356K

Select item 314723217.

Meta-analysis of genome-wide association studies in >80,000 subjects identifies multiple loci for C-reactive protein levels

Abbas Dehghan, Josée Dupuis, Maja Barbalic, Joshua C Bis, Gudny Eiriksdottir, Chen Lu, Niina Pellikka, Henri Wallaschofski, Johannes Kettunen, Peter Henneman, Jens Baumert, David P Strachan, Christian Fuchsberger, Veronique Vitart, James F Wilson, Guillaume Paré, Silvia Naitza, Megan E Rudock, Ida Surakka, Eco JC de Geus, Behrooz Z Alizadeh, Jack Guralnik, Alan Shuldiner, Toshiko Tanaka, Robert YL Zee, Renate B Schnabel, Vijay Nambi, Maryam Kavousi, Samuli Ripatti, Matthias Nauck, Nicholas L Smith, Albert V Smith, Jouko Sundvall, Paul Scheet, Yongmei Liu, Aimo Ruokonen, Lynda M Rose, Martin G Larson, Ron C Hoogeveen, Nelson B Freimer, Alexander Teumer, Russell P Tracy, Lenore J Launer, Julie E Buring, Jennifer F Yamamoto, Aaron R Folsom, Eric JG Sijbrands, James Pankow, Paul Elliott, John F Keaney, Wei Sun, Antti-Pekka Sarin, João D Fontes, Sunita Badola, Brad C Astor, Albert Hofman, Anneli Pouta, Karl Werdan, Karin H Greiser, Oliver Kuss, Henriette E Meyer zu Schwabedissen, Joachim Thiery, Yalda Jamshidi, Ilja M Nolte, Nicole Soranzo, Timothy D Spector, Henry Völzke, Alexander N Parker, Thor Aspelund, David Bates, Lauren Young, Kim Tsui, David S Siscovick, Xiuqing Guo, Jerome I Rotter, Manuela Uda, David Schlessinger, Igor Rudan, Andrew A Hicks, Brenda W Penninx, Barbara Thorand, Christian Gieger, Joe Coresh, Gonneke Willemsen, Tamara B Harris, Andre G Uitterlinden, Marjo-Riitta Järvelin, Kenneth Rice, Dörte Radke, Veikko Salomaa, Ko Willems van Dijk, Eric Boerwinkle, Ramachandran S Vasan, Luigi Ferrucci, Quince D Gibson, Stefania Bandinelli, Harold Snieder, Dorret I Boomsma, Xiangjun Xiao, Harry Campbell, Caroline Hayward, Peter P Pramstaller, Cornelia M van Duijn, Leena Peltonen, Bruce M Psaty, Vilmundur Gudnason, Paul M Ridker, Georg Homuth, Wolfgang Koenig, Christie M Ballantyne, Jacqueline CM Witteman, Emelia J Benjamin, Markus Perola, Daniel I Chasman

Circulation. Author manuscript; available in PMC 2011 Aug 1.

Published in final edited form as: Circulation. 2011 Feb 22; 123(7): 731–738. Published online 2011 Feb 7. doi: 10.1161/CIRCULATIONAHA.110.948570

PMCID:: PMC3147232

Abstract Article PDF–336K

Select item 143538218.

Identification of a Novel Extracellular Cation-sensing G-protein-coupled Receptor

Min Pi, Pieter Faber, George Ekema, P. David Jackson, Anthony Ting, Nancy Wang, Michelle Fontilla-Poole, Robert W. Mays, Kurt R. Brunden, John J. Harrington, L. Darryl Quarles

J Biol Chem. Author manuscript; available in PMC 2006 Apr 11.

Published in final edited form as: J Biol Chem. 2005 Dec 2; 280(48): 40201–40209. Published online 2005 Sep 30. doi: 10.1074/jbc.M505186200

PMCID:: PMC1435382

Abstract Article PDF–512K

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