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Items: 1 to 20 of 115

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Overexpression of Constitutively Active PKG-I Protects Female, But Not Male Mice From Diet-Induced Obesity
Dejan M. Nikolic, Yanzhang Li, Shu Liu, Shuxia Wang
Obesity (Silver Spring) Author manuscript; available in PMC 2022 May 23.
Published in final edited form as: Obesity (Silver Spring). 2011 Apr; 19(4): 784–791. Published online 2010 Oct 7. doi: 10.1038/oby.2010.223
PMCID:
PMC9125568
AbstractArticlePDF–1.4M
3.
Ferulic acid ameliorates lipopolysaccharide-induced tracheal injury via cGMP/PKGII signaling pathway
Xiaoyong Xie, Tong Yu, Yapeng Hou, Aixin Han, Yan Ding, Hongguang Nie, Yong Cui
Respir Res. 2021; 22: 308. Published online 2021 Dec 4. doi: 10.1186/s12931-021-01897-4
PMCID:
PMC8642995
AbstractArticlePDF–6.1M
4.
Cyclic GMP-Dependent Regulation of Vascular Tone and Blood Pressure Involves Cysteine-Rich LIM-Only Protein 4 (CRP4)
Natalie Längst, Julia Adler, Olga Schweigert, Felicia Kleusberg, Melanie Cruz Santos, Amelie Knauer, Matthias Sausbier, Tanja Zeller, Peter Ruth, Robert Lukowski
Int J Mol Sci. 2021 Sep; 22(18): 9925. Published online 2021 Sep 14. doi: 10.3390/ijms22189925
PMCID:
PMC8466836
AbstractArticlePDF–3.1M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
The endothelial nitric oxide synthase/cyclic guanosine monophosphate/protein kinase G pathway activates primordial follicles
Peikun Zhao, Zidai Song, Yan Wang, Han Cai, Xiaoyan Du, Changlong Li, Jianyi Lv, Xin Liu, Meng Guo, Zhenwen Chen
Aging (Albany NY) 2021 Jan 15; 13(1): 1096–1119. Published online 2020 Dec 3. doi: 10.18632/aging.202235
PMCID:
PMC7835019
AbstractArticlePDF–4.1M
7.
Protein kinase G1 regulates bone regeneration and rescues diabetic fracture healing
Nadine Schall, Julian J. Garcia, Hema Kalyanaraman, Shyamsundar Pal China, Jenna J. Lee, Robert L. Sah, Alexander Pfeifer, Renate B. Pilz
JCI Insight. 2020 May 7; 5(9): e135355. Published online 2020 May 7. doi: 10.1172/jci.insight.135355
PMCID:
PMC7253025
AbstractArticlePDF–34M
8.
Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling
Martin Feelisch, Takaaki Akaike, Kayleigh Griffiths, Tomoaki Ida, Oleksandra Prysyazhna, Joanna J Goodwin, Nicholas D Gollop, Bernadette O Fernandez, Magdalena Minnion, Miriam M Cortese-Krott, Alessandra Borgognone, Rosie M Hayes, Philip Eaton, Michael P Frenneaux, Melanie Madhani
Cardiovasc Res. 2020 Jan 1; 116(1): 51–62. Published online 2019 Aug 1. doi: 10.1093/cvr/cvz202
PMCID:
PMC6918062
AbstractArticlePDF–1.2M
9.
cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice
Maria Shvedova, Maxim M Litvak, Jesse D Roberts, Jr., Dai Fukumura, Tomoaki Suzuki, İkbal Şencan, Ge Li, Paula Reventun, Emmanuel S Buys, Hyung-Hwan Kim, Sava Sakadžić, Cenk Ayata, Paul L Huang, Robert Feil, Dmitriy N Atochin
J Cereb Blood Flow Metab. 2019 Dec; 39(12): 2379–2391. Published online 2019 Aug 18. doi: 10.1177/0271678X19870583
PMCID:
PMC6893979
AbstractArticlePDF–1.0M
10.
Long-Term Potentiation in the Hippocampal CA1 Region of Mice Lacking cGMP-Dependent Kinases Is Normal and Susceptible to Inhibition of Nitric Oxide Synthase
Thomas Kleppisch, Alexander Pfeifer, Peter Klatt, Peter Ruth, Alexandra Montkowski, Reinhard Fässler, Franz Hofmann
J Neurosci. 1999 Jan 1; 19(1): 48–55. doi: 10.1523/JNEUROSCI.19-01-00048.1999
PMCID:
PMC6782378
AbstractArticlePDF–290K
11.
Hippocampal cGMP-Dependent Protein Kinase I Supports an Age- and Protein Synthesis-Dependent Component of Long-Term Potentiation But Is Not Essential for Spatial Reference and Contextual Memory
Thomas Kleppisch, Wiebke Wolfsgruber, Susanne Feil, Rüdiger Allmann, Carsten T. Wotjak, Sandra Goebbels, Klaus-Armin Nave, Franz Hofmann, Robert Feil
J Neurosci. 2003 Jul 9; 23(14): 6005–6012. doi: 10.1523/JNEUROSCI.23-14-06005.2003
PMCID:
PMC6740356
AbstractArticlePDF–408K
12.
Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog
Gerburg K. Schwaerzer, Hema Kalyanaraman, Darren E. Casteel, Nancy D. Dalton, Yusu Gu, Seunghoe Lee, Shunhui Zhuang, Nisreen Wahwah, Jan M. Schilling, Hemal H. Patel, Qian Zhang, Ayako Makino, Dianna M. Milewicz, Kirk L. Peterson, Gerry R. Boss, Renate B. Pilz
Nat Commun. 2019; 10: 3533. Published online 2019 Aug 6. doi: 10.1038/s41467-019-11389-1
PMCID:
PMC6684604
AbstractArticlePDF–2.9M
13.
Cysteine-Rich Protein 2, a Novel Downstream Effector of cGMP/cGMP-Dependent Protein Kinase I-Mediated Persistent Inflammatory Pain
Achim Schmidtko, Wei Gao, Matthias Sausbier, Inga Rauhmeier, Ulrike Sausbier, Ellen Niederberger, Klaus Scholich, Andrea Huber, Winfried Neuhuber, Hans-Dieter Allescher, Franz Hofmann, Irmgard Tegeder, Peter Ruth, Gerd Geisslinger
J Neurosci. 2008 Feb 6; 28(6): 1320–1330. doi: 10.1523/JNEUROSCI.5037-07.2008
PMCID:
PMC6671575
AbstractArticlePDF–627K
14.
Protein Kinase G Dynamically Modulates TASK1-Mediated Leak K+ Currents in Cholinergic Neurons of the Basal Forebrain
Hiroki Toyoda, Mitsuru Saito, Makoto Okazawa, Keiko Hirao, Hajime Sato, Haruka Abe, Kenji Takada, Kazuo Funabiki, Masahiko Takada, Takeshi Kaneko, Youngnam Kang
J Neurosci. 2010 Apr 21; 30(16): 5677–5689. doi: 10.1523/JNEUROSCI.5407-09.2010
PMCID:
PMC6632358
AbstractArticlePDF–3.2M
15.
Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling
Gohar Ter-Avetisyan, Fritz G. Rathjen, Hannes Schmidt
J Neurosci. 2014 Jan 15; 34(3): 737–747. doi: 10.1523/JNEUROSCI.4183-13.2014
PMCID:
PMC6608349
AbstractArticlePDF–5.5M
16.
Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension
Olena Rudyk, Alice Rowan, Oleksandra Prysyazhna, Susanne Krasemann, Kristin Hartmann, Min Zhang, Ajay M. Shah, Clemens Ruppert, Astrid Weiss, Ralph T. Schermuly, Tomoaki Ida, Takaaki Akaike, Lan Zhao, Philip Eaton
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 13016–13025. Published online 2019 Jun 11. doi: 10.1073/pnas.1904064116
PMCID:
PMC6601250
AbstractArticlePDF–2.1M
17.
Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons
Hannes Schmidt, Deborah M. Dickey, Alexandre Dumoulin, Marie Octave, Jerid W. Robinson, Ralf Kühn, Robert Feil, Lincoln R. Potter, Fritz G. Rathjen
J Neurosci. 2018 Nov 7; 38(45): 9768–9780. doi: 10.1523/JNEUROSCI.0495-18.2018
PMCID:
PMC6222061
AbstractArticlePDF–2.9M
18.
A shear-dependent NO-cGMP-cGKI cascade in platelets acts as an auto-regulatory brake of thrombosis
Lai Wen, Susanne Feil, Markus Wolters, Martin Thunemann, Frank Regler, Kjestine Schmidt, Andreas Friebe, Marcus Olbrich, Harald Langer, Meinrad Gawaz, Cor de Wit, Robert Feil
Nat Commun. 2018; 9: 4301. Published online 2018 Oct 16. doi: 10.1038/s41467-018-06638-8
Correction in:
Nat Commun. 2018; 9: 4969.
PMCID:
PMC6191445
AbstractArticlePDF–2.0M
19.
S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling
Alexandre Dumoulin, Alina Dagane, Gunnar Dittmar, Fritz G. Rathjen
Front Mol Neurosci. 2018; 11: 345. Published online 2018 Sep 24. doi: 10.3389/fnmol.2018.00345
PMCID:
PMC6166100
AbstractArticlePDF–4.3M
20.
TNF-α elicits phenotypic and functional alterations of vascular smooth muscle cells by miR-155-5p–dependent down-regulation of cGMP-dependent kinase 1
Seunghwan Choi, Minsik Park, Joohwan Kim, Wonjin Park, Suji Kim, Dong-Keon Lee, Jong Yun Hwang, Jongseon Choe, Moo-Ho Won, Sungwoo Ryoo, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
J Biol Chem. 2018 Sep 21; 293(38): 14812–14822. Published online 2018 Aug 13. doi: 10.1074/jbc.RA118.004220
PMCID:
PMC6153283
AbstractArticlePDF–2.3M

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