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Items: 1 to 20 of 258

1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability
YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek
Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x
PMCID:
PMC11148184
AbstractArticlePDF–8.1M
2.
DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer
Yinghong Xie, Yuancheng Li, Mengzhu Yang
J Immunol Res. 2023; 2023: 5041223. Published online 2023 Dec 13. doi: 10.1155/2023/5041223
PMCID:
PMC10732869
AbstractArticlePDF–5.7M
3.
TrkB inhibition of DJ-1 degradation promotes the growth and maintenance of cancer stem cell characteristics in hepatocellular carcinoma
Min Soo Kim, Won Sung Lee, Wook Jin
Cell Mol Life Sci. 2023 Oct; 80(10): 303. Published online 2023 Sep 25. doi: 10.1007/s00018-023-04960-z
PMCID:
PMC10520132
AbstractArticlePDF–2.6M
4.
Disease-Modifying Effects of Vincamine Supplementation in Drosophila and Human Cell Models of Parkinson’s Disease Based on DJ-1 Deficiency
Francisco José Sanz, Cristina Solana-Manrique, Nuria Paricio
ACS Chem Neurosci. 2023 Jun 21; 14(12): 2294–2301. Published online 2023 Jun 8. doi: 10.1021/acschemneuro.3c00026
PMCID:
PMC10288506
AbstractArticlePDF–2.7M
5.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
6.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
7.
Kinetic evidence in favor of glyoxalase III and against deglycase activity of DJ‐1
Joonhyeok Choi, Sungho Tak, Hoe‐Myung Jung, Soyoung Cha, Eunha Hwang, Donghan Lee, Joon‐Hwa Lee, Kyoung‐Seok Ryu, Chankyu Park
Protein Sci. 2023 May; 32(5): e4641. Published online 2023 May 1. doi: 10.1002/pro.4641
PMCID:
PMC10127264
AbstractArticlePDF–2.6M
8.
PARK7/DJ-1 in microglia: implications in Parkinson’s disease and relevance as a therapeutic target
Frida Lind-Holm Mogensen, Andrea Scafidi, Aurélie Poli, Alessandro Michelucci
J Neuroinflammation. 2023; 20: 95. Published online 2023 Apr 18. doi: 10.1186/s12974-023-02776-z
PMCID:
PMC10111685
AbstractArticlePDF–1.9M
9.
Parkinsonism-Associated Protein DJ-1 Is an Antagonist, Not an Eraser, for Protein Glycation
Qingzeng Gao, Jeremiah W. Jacob-Dolan, Rebecca A. Scheck
Biochemistry. 2023 Mar 21; 62(6): 1181–1190. Published online 2023 Feb 23. doi: 10.1021/acs.biochem.3c00028
PMCID:
PMC10035033
AbstractArticlePDF–10M
10.
Fibril treatment changes protein interactions of tau and α-synuclein in human neurons
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker, George A. Carlson
J Biol Chem. 2023 Mar; 299(3): 102888. Published online 2023 Jan 10. doi: 10.1016/j.jbc.2023.102888
PMCID:
PMC9978635
AbstractArticlePDF–10M
11.
Searching for Biomarkers in the Blood of Patients at Risk of Developing Parkinson’s Disease at the Prodromal Stage
Elena A. Katunina, Victor Blokhin, Marina R. Nodel, Ekaterina N. Pavlova, Alexander L. Kalinkin, Valerian G. Kucheryanu, Leyla Alekperova, Marianna V. Selikhova, Mikhail Yu. Martynov, Michael V. Ugrumov
Int J Mol Sci. 2023 Feb; 24(3): 1842. Published online 2023 Jan 17. doi: 10.3390/ijms24031842
PMCID:
PMC9915927
AbstractArticlePDF–5.3M
12.
DJ-1 is an essential downstream mediator in PINK1/parkin-dependent mitophagy
Dorien Imberechts, Inge Kinnart, Fieke Wauters, Joanne Terbeek, Liselot Manders, Keimpe Wierda, Kristel Eggermont, Rodrigo Furtado Madeiro, Carolyn Sue, Catherine Verfaillie, Wim Vandenberghe
Brain. 2022 Dec; 145(12): 4368–4384. Published online 2022 Aug 30. doi: 10.1093/brain/awac313
PMCID:
PMC9762950
AbstractArticlePDF–2.0M
13.
MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer
Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang
Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x
PMCID:
PMC9523997
AbstractArticlePDF–6.9M
14.
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein
Marius Walter, Irene P. Chen, Albert Vallejo-Gracia, Ik-Jung Kim, Olga Bielska, Victor L. Lam, Jennifer M. Hayashi, Andrew Cruz, Samah Shah, Frank W. Soveg, John D. Gross, Nevan J. Krogan, Keith R. Jerome, Birgit Schilling, Melanie Ott, Eric Verdin
PLoS Pathog. 2022 Sep; 18(9): e1010811. Published online 2022 Sep 12. doi: 10.1371/journal.ppat.1010811
PMCID:
PMC9499238
AbstractArticlePDF–3.7M
15.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
16.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
PMCID:
PMC9440653
AbstractArticlePDF–2.9M
17.
SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation–Phosphorylation Cross-talk
Valentina Lukinović, Simone Hausmann, Gael S. Roth, Clement Oyeniran, Tanveer Ahmad, Ning Tsao, Joshua R. Brickner, Alexandre G. Casanova, Florent Chuffart, Ana Morales Benitez, Jessica Vayr, Rebecca Rodell, Marianne Tardif, Pascal W.T.C. Jansen, Yohann Couté, Michiel Vermeulen, Pierre Hainaut, Pawel K. Mazur, Nima Mosammaparast, Nicolas Reynoird
Cancer Discov. 2022 Sep 2; 12(9): 2158–2179. Published online 2022 Jul 12. doi: 10.1158/2159-8290.CD-21-0205
PMCID:
PMC9437563
AbstractArticlePDF–9.5M
18.
PARKIN, PINK1 and DJ1 analysis in early onset Parkinson’s disease in Ireland
Diana A. Olszewska, Allan McCarthy, Alexandra I. Soto-Beasley, Ronald L. Walton, Owen A. Ross, Tim Lynch
Ir J Med Sci. Author manuscript; available in PMC 2023 Apr 1.
Published in final edited form as: Ir J Med Sci. 2022 Apr; 191(2): 901–907. Published online 2021 Mar 22. doi: 10.1007/s11845-021-02563-w
PMCID:
PMC9376961
AbstractArticlePDF–491K
19.
DJ-1 controls T cell differentiation and osteoclastogenesis in rheumatoid arthritis
Hong Ki Min, Se Hee Kim, Ji-Yeon Lee, Sang-Heon Lee, Hae-Rim Kim
Sci Rep. 2022; 12: 12767. Published online 2022 Jul 27. doi: 10.1038/s41598-022-16285-1
PMCID:
PMC9329329
AbstractArticlePDF–3.8M
20.
Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex‐dependent regulation of glycolysis
Matthew E. R. Maitland, Miljan Kuljanin, Xu Wang, Gilles A. Lajoie, Caroline Schild‐Poulter
FASEB J. 2021 Sep; 35(9): e21825. Published online 2021 Aug 12. doi: 10.1096/fj.202100664R
PMCID:
PMC9292413
AbstractArticlePDF–1.5M

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