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Select item 107869141.

PIEZO2 expression is an independent biomarker prognostic for gastric cancer and represents a potential therapeutic target

Yun-Chao Zhang, Min Yang, Cen-di Lu, Quan-Yao Li, Jin-na Shi, Jun Shi

Sci Rep. 2024; 14: 1206. Published online 2024 Jan 12. doi: 10.1038/s41598-023-48577-5

PMCID:: PMC10786914

Abstract Article PDF–8.7M

Select item 107318872.

Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics

Arjun Raha, Yuning Wu, Lily Zhong, Jatheeshan Raveenthiran, Minji Hong, Aftab Taiyab, Li Wang, Bill Wang, Fei Geng

Mol Brain. 2023; 16: 83. Published online 2023 Dec 20. doi: 10.1186/s13041-023-01071-5

PMCID:: PMC10731887

Abstract Article PDF–3.8M

Select item 106077053.

Disrupted Neural Regeneration in Dry Eye Secondary to Ankylosing Spondylitis—With a Theoretical Link between Piezo2 Channelopathy and Gateway Reflex, WDR Neurons, and Flare-Ups

Balázs Sonkodi, László Marsovszky, Anita Csorba, Attila Balog, Bence Kopper, Anikó Keller-Pintér, Zoltán Zsolt Nagy, Miklós D. Resch

Int J Mol Sci. 2023 Oct; 24(20): 15455. Published online 2023 Oct 22. doi: 10.3390/ijms242015455

PMCID:: PMC10607705

Abstract Article PDF–1.4M

Select item 105013184.

PIEZO2 in somatosensory neurons controls gastrointestinal transit

M. Rocio Servin-Vences, Ruby M. Lam, Alize Koolen, Yu Wang, Dimah N. Saade, Meaghan Loud, Halil Kacmaz, Suzanne Frausto, Yunxiao Zhang, Arthur Beyder, Kara L. Marshall, Carsten G. Bönnemann, Alexander T. Chesler, Ardem Patapoutian

Cell. Author manuscript; available in PMC 2023 Sep 14.

Published in final edited form as: Cell. 2023 Aug 3; 186(16): 3386–3399.e15. doi: 10.1016/j.cell.2023.07.006

PMCID:: PMC10501318

Abstract Article PDF–1.0M

Select item 104160895.

Common Genetic Variation and Antidepressant Efficacy in Major Depressive Disorder: A Meta-Analysis of Three Genome-Wide Pharmacogenetic Studies

GENDEP Investigators, Rudolf Uher, Katherine E. Tansey, Marcella Rietschel, Neven Henigsberg, Wolfgang Maier, Ole Mors, Joanna Hauser, Anna Placentino, Daniel Souery, Anne Farmer, Katherine J. Aitchison, Ian Craig, Peter McGuffin, Cathryn M. Lewis, MARS Investigators, Marcus Ising, Susanne Lucae, Elisabeth B. Binder, Stefan Kloiber, Florian Holsboer, Bertram Müller-Myhsok, STAR*D Investigators, Stephan Ripke, Steven P. Hamilton, Jared Soundy, Gonzalo Laje, Francis J. McMahon, Maurizio Fava, A. John Rush, Roy H. Perlis

Am J Psychiatry. Author manuscript; available in PMC 2023 Aug 11.

Published in final edited form as: Am J Psychiatry. 2013 Feb; 170(2): 207–217. doi: 10.1176/appi.ajp.2012.12020237

PMCID:: PMC10416089

Abstract Article PDF–1.4M

Select item 102404226.

PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2

Irina Schaefer, Clement Verkest, Lucas Vespermann, Thomas Mair, Hannah Voß, Nadja Zeitzschel, Stefan G. Lechner

J Biol Chem. 2023 Jun; 299(6): 104782. Published online 2023 May 4. doi: 10.1016/j.jbc.2023.104782

PMCID:: PMC10240422

Abstract Article PDF–7.8M

Select item 101488227.

Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis

Alia M. Obeidat, Matthew J. Wood, Natalie S. Adamczyk, Shingo Ishihara, Jun Li, Lai Wang, Dongjun Ren, David A. Bennett, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller

Nat Commun. 2023; 14: 2479. Published online 2023 Apr 29. doi: 10.1038/s41467-023-38241-x

PMCID:: PMC10148822

Abstract Article PDF–2.7M

Select item 100270928.

The role of PIEZO ion channels in the musculoskeletal system

Alireza Savadipour, Daniel Palmer, Erica V. Ely, Kelsey H. Collins, Jaquelin M. Garcia-Castorena, Zainab Harissa, Yu Seon Kim, Arin Oestrich, Feini Qu, Neda Rashidi, Farshid Guilak

Am J Physiol Cell Physiol. 2023 Mar 1; 324(3): C728–C740. Published online 2023 Jan 30. doi: 10.1152/ajpcell.00544.2022

PMCID:: PMC10027092

Abstract Article

Select item 93747899.

Is the Sex Difference a Clue to the Pathomechanism of Dry Eye Disease? Watch out for the NGF-TrkA-Piezo2 Signaling Axis and the Piezo2 Channelopathy

Balázs Sonkodi, Miklós D. Resch, Tibor Hortobágyi

J Mol Neurosci. 2022; 72(8): 1598–1608. Published online 2022 May 4. doi: 10.1007/s12031-022-02015-9

PMCID:: PMC9374789

Abstract Article PDF–1.0M

Select item 933615610.

Distal Arthrogryposis type 5 in an Italian family due to an autosomal dominant gain-of-function mutation of the PIEZO2 gene

Gregorio Serra, Vincenzo Antona, Chiara Cannata, Mario Giuffrè, Ettore Piro, Ingrid Anne Mandy Schierz, Giovanni Corsello

Ital J Pediatr. 2022; 48: 133. Published online 2022 Jul 29. doi: 10.1186/s13052-022-01329-z

PMCID:: PMC9336156

Abstract Article PDF–990K

Select item 911401211.

Piezo2 is not an indispensable mechanosensor in murine cardiomyocytes

Benjamin Kloth, Giulia Mearini, Florian Weinberger, Justus Stenzig, Birgit Geertz, Jutta Starbatty, Diana Lindner, Udo Schumacher, Hermann Reichenspurner, Thomas Eschenhagen, Marc N. Hirt

Sci Rep. 2022; 12: 8193. Published online 2022 May 17. doi: 10.1038/s41598-022-12085-9

PMCID:: PMC9114012

Abstract Article PDF–2.1M

Select item 879400412.

The Form and Function of PIEZO2

Marcin Szczot, Alec R. Nickolls, Ruby M. Lam, Alexander T. Chesler

Annu Rev Biochem. Author manuscript; available in PMC 2022 Jan 27.

Published in final edited form as: Annu Rev Biochem. 2021 Jun 20; 90: 507–534. doi: 10.1146/annurev-biochem-081720-023244

PMCID:: PMC8794004

Abstract Article PDF–2.4M

Select item 864338513.

Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels

Ru-Rong Ji, Seok-Yong Lee

Neurosci Bull. 2021 Dec; 37(12): 1745–1749. Published online 2021 Nov 25. doi: 10.1007/s12264-021-00798-2

PMCID:: PMC8643385

Article PDF–783K

Select item 836418114.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 821950615.

Piezo2 downregulation via the Cre-lox system affects aqueous humor dynamics in mice

Jingwang Fang, Fei Hou, Shen Wu, Yani Liu, Linna Wang, Jingxue Zhang, Ningli Wang, Kewei Wang, Wei Zhu

Mol Vis. 2021; 27: 354–364. Published online 2021 May 20.

PMCID:: PMC8219506

Abstract Article PDF–3.4M

Select item 781212516.

Glans clitoris innervation: PIEZO2 and sexual mechanosensitivity

Yolanda García‐Mesa, Lucía Cárcaba, César Coronado, Ramón Cobo, José Martín‐Cruces, Jorge García‐Piqueras, Jorge Feito, Olivia García‐Suárez, José A. Vega

J Anat. 2021 Feb; 238(2): 446–454. Published online 2020 Sep 29. doi: 10.1111/joa.13317

PMCID:: PMC7812125

Abstract Article PDF–1.3M

Select item 772587817.

PIEZO2 in sensory neurons and urothelial cells coordinates urination

Kara L. Marshall, Dimah Saade, Nima Ghitani, Adam M. Coombs, Marcin Szczot, Jason Keller, Tracy Ogata, Ihab Daou, Lisa T. Stowers, Carsten G. Bönnemann, Alexander T. Chesler, Ardem Patapoutian

Nature. Author manuscript; available in PMC 2021 Apr 14.

Published in final edited form as: Nature. 2020 Dec; 588(7837): 290–295. Published online 2020 Oct 14. doi: 10.1038/s41586-020-2830-7

PMCID:: PMC7725878

Abstract Article PDF–2.9M

Select item 730517918.

A dietary fatty acid counteracts neuronal mechanical sensitization

Luis O. Romero, Rebeca Caires, Alec R. Nickolls, Alexander T. Chesler, Julio F. Cordero-Morales, Valeria Vásquez

Nat Commun. 2020; 11: 2997. Published online 2020 Jun 19. doi: 10.1038/s41467-020-16816-2

Correction in:: Nat Commun. 2020; 11: 3938.

PMCID:: PMC7305179

Abstract Article PDF–12M

Select item 705010319.

AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair

Zhen Chen, Chao Wang, Antrix Jain, Mrinal Srivastava, Mengfan Tang, Huimin Zhang, Xu Feng, Litong Nie, Dan Su, Yun Xiong, Sung Yun Jung, Jun Qin, Junjie Chen

Mol Cell Proteomics. 2020 Mar; 19(3): 467–477. Published online 2020 Jan 3. doi: 10.1074/mcp.RA119.001794

PMCID:: PMC7050103

Abstract Article PDF–1.8M

Select item 687577420.

PIEZO2 mediates injury-induced tactile pain in mice and humans

Marcin Szczot, Jaquette Liljencrantz, Nima Ghitani, Arnab Barik, Ruby Lam, James H. Thompson, Diana Bharucha-Goebel, Dimah Saade, Aaron Necaise, Sandra Donkervoort, A. Reghan Foley, Taylor Gordon, Laura Case, M. Catherine Bushnell, Carsten G. Bönnemann, Alexander T. Chesler

Sci Transl Med. Author manuscript; available in PMC 2019 Nov 25.

Published in final edited form as: Sci Transl Med. 2018 Oct 10; 10(462): eaat9892. doi: 10.1126/scitranslmed.aat9892

PMCID:: PMC6875774

Abstract Article PDF–1.7M

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