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Select item 111139821.

Ube3a, the E3 ubiquitin ligase causing Angelman syndrome and linked to autism, regulates protein homeostasis through the proteasomal shuttle Rpn10

So Young Lee, Juanma Ramirez, Maribel Franco, Benoît Lectez, Monika Gonzalez, Rosa Barrio, Ugo Mayor

Cell Mol Life Sci. 2014 Jul; 71(14): 2747–2758. Published online 2013 Dec 1. doi: 10.1007/s00018-013-1526-7

PMCID:: PMC11113982

Abstract Article PDF–1.7M

Select item 92738682.

Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform

Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov

Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017

PMCID:: PMC9273868

Abstract Article PDF–3.6M

Select item 87444523.

Base Editing of Somatic Cells Using CRISPR–Cas9 in Drosophila

Elizabeth Marr, Christopher J. Potter

CRISPR J. December 2021; 4(6): 836–845. Published online 2021 Dec 16. doi: 10.1089/crispr.2021.0062

PMCID:: PMC8744452

Abstract Article PDF–1.1M

Select item 86452074.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 81049465.

Highly effective proximate labeling in Drosophila

Bo Zhang, Yuanbing Zhang, Ji-Long Liu

G3 (Bethesda) 2021 May; 11(5): jkab077. Published online 2021 Mar 16. doi: 10.1093/g3journal/jkab077

Correction in:: G3 (Bethesda). 2022 Mar; 12(3): jkac005.

PMCID:: PMC8104946

Abstract Article PDF–1.1M

Select item 80523436.

DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells

Lama Tarayrah-Ibraheim, Elital Chass Maurice, Guy Hadary, Sharon Ben-Hur, Alina Kolpakova, Tslil Braun, Yoav Peleg, Keren Yacobi-Sharon, Eli Arama

Nat Commun. 2021; 12: 2285. Published online 2021 Apr 16. doi: 10.1038/s41467-021-22622-1

PMCID:: PMC8052343

Abstract Article PDF–8.8M

Select item 80422707.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 70110838.

A Drosophila Model for Clostridium difficile Toxin CDT Reveals Interactions with Multiple Effector Pathways

Ruth Schwartz, Annabel Guichard, Nathalie C. Franc, Sitara Roy, Ethan Bier

iScience. 2020 Feb 21; 23(2): 100865. Published online 2020 Jan 25. doi: 10.1016/j.isci.2020.100865

PMCID:: PMC7011083

Abstract Article PDF–40M

Select item 69615789.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 650653910.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 607860411.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 570780512.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900213.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 534099814.

A Luciferase-fragment Complementation Assay to Detect Lipid Droplet-associated Protein-Protein Interactions

Petra Kolkhof, Michael Werthebach, Anna van de Venn, Gereon Poschmann, Lili Chen, Michael Welte, Kai Stühler, Mathias Beller

Mol Cell Proteomics. 2017 Mar; 16(3): 329–345. Published online 2016 Dec 12. doi: 10.1074/mcp.M116.061499

PMCID:: PMC5340998

Abstract Article PDF–3.8M

Select item 512686415.

Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster

Punita Juneja, Andrew Quinn, Francis M. Jiggins

BMC Genomics. 2016; 17: 981. Published online 2016 Nov 28. doi: 10.1186/s12864-016-3333-7

PMCID:: PMC5126864

Abstract Article PDF–1.1M

Select item 507911116.

C9orf72 dipeptide repeats impair the assembly, dynamics and function of membrane-less organelles

Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana Mitrea, Mohona Sarkar, Brian Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex, Brian Maxwell, Nam Chul Kim, Jamshid Temirov, Jennifer Moore, Regina-Maria Kolaitis, Timothy Shaw, Bing Bai, Junmin Peng, Richard Kriwacki, J. Paul Taylor

Cell. Author manuscript; available in PMC 2017 Oct 20.

Published in final edited form as: Cell. 2016 Oct 20; 167(3): 774–788.e17. doi: 10.1016/j.cell.2016.10.002