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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106219962.

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1

Alexandre Pierga, Raphaël Matusiak, Margaux Cauhapé, Julien Branchu, Lydia Danglot, Maxime Boutry, Frédéric Darios

PLoS Biol. 2023 Oct; 21(10): e3002337. Published online 2023 Oct 23. doi: 10.1371/journal.pbio.3002337

PMCID:: PMC10621996

Abstract Article PDF–9.2M

Select item 100428293.

Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity

Shuwen He, John P. Gillies, Juliana L. Zang, Carmen M. Córdoba-Beldad, Io Yamamoto, Yasuhiro Fujiwara, Julie Grantham, Morgan E. DeSantis, Hiroki Shibuya

Nat Commun. 2023; 14: 1715. Published online 2023 Mar 27. doi: 10.1038/s41467-023-37370-7

PMCID:: PMC10042829

Abstract Article PDF–4.3M

Select item 99888874.

Deficiency of Perry syndrome-associated p150^Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities

Jia Yu, Xuan Yang, Jiayin Zheng, Carmelo Sgobio, Lixin Sun, Huaibin Cai

NPJ Parkinsons Dis. 2023; 9: 35. Published online 2023 Mar 7. doi: 10.1038/s41531-023-00478-0

PMCID:: PMC9988887

Abstract Article PDF–13M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819336.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 93044087.

Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex

Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner

Nat Commun. 2022; 13: 4209. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31752-z

PMCID:: PMC9304408

Abstract Article PDF–13M

Select item 85785078.

Functional assessment of the V390F mutation in the CCTδ subunit of chaperonin containing tailless complex polypeptide 1

Josefine Vallin, Julie Grantham

Cell Stress Chaperones. 2021 Nov; 26(6): 955–964. Published online 2021 Oct 15. doi: 10.1007/s12192-021-01237-x

PMCID:: PMC8578507

Abstract Article PDF–1.8M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 810206010.

DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction

Eva On-Chai Lau, Devid Damiani, Georges Chehade, Nuria Ruiz-Reig, Rana Saade, Yves Jossin, Mohamed Aittaleb, Olivier Schakman, Nicolas Tajeddine, Philippe Gailly, Fadel Tissir

eLife. 2021; 10: e61974. Published online 2021 Apr 26. doi: 10.7554/eLife.61974

PMCID:: PMC8102060

Abstract Article PDF–3.8M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 781472512.

Schizophrenia-associated dysbindin modulates axonal mitochondrial movement in cooperation with p150^glued

Bo Kyoung Suh, Seol-Ae Lee, Cana Park, Yeongjun Suh, Soo Jeong Kim, Youngsik Woo, Truong Thi My Nhung, Su Been Lee, Dong Jin Mun, Bon Seong Goo, Hyun Sun Choi, So Jung Kim, Sang Ki Park

Mol Brain. 2021; 14: 14. Published online 2021 Jan 18. doi: 10.1186/s13041-020-00720-3

PMCID:: PMC7814725

Abstract Article PDF–2.0M

Select item 715641113.

The dynactin subunit DCTN1 controls osteoclastogenesis via the Cdc42/PAK2 pathway

Yong Deok Lee, Bongjun Kim, Suhan Jung, Haemin Kim, Min Kyung Kim, Jun-Oh Kwon, Min-Kyoung Song, Zang Hee Lee, Hong-Hee Kim

Exp Mol Med. 2020 Mar; 52(3): 514–528. Published online 2020 Mar 24. doi: 10.1038/s12276-020-0406-0

PMCID:: PMC7156411

Abstract Article PDF–7.4M

Select item 699392514.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 695997815.

Telophase correction refines division orientation in stratified epithelia

Kendall J Lough, Kevin M Byrd, Carlos P Descovich, Danielle C Spitzer, Abby J Bergman, Gerard MJ Beaudoin, III, Louis F Reichardt, Scott E Williams

eLife. 2019; 8: e49249. Published online 2019 Dec 13. doi: 10.7554/eLife.49249

PMCID:: PMC6959978

Abstract Article PDF–5.4M

Select item 672506916.

Axonal Dynactin p150^Glued Transports Caspase-8 to Drive Retrograde Olfactory Receptor Neuron Apoptosis

Christine Carson, Maya Saleh, France W. Fung, Donald W. Nicholson, A. Jane Roskams

J Neurosci. 2005 Jun 29; 25(26): 6092–6104. doi: 10.1523/JNEUROSCI.0707-05.2005

PMCID:: PMC6725069

Abstract Article PDF–910K

Select item 645951017.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194