PMC Links for GEO Profiles (Select 5176429) - PMC

Select item 67252091.

APH-1a Is the Principal Mammalian APH-1 Isoform Present in γ-Secretase Complexes during Embryonic Development

Guojun Ma, Tong Li, Donald L. Price, Philip C. Wong

J Neurosci. 2005 Jan 5; 25(1): 192–198. doi: 10.1523/JNEUROSCI.3814-04.2005

PMCID:: PMC6725209

Select item 66728272.

Moderate Reduction of γ-Secretase Attenuates Amyloid Burden and Limits Mechanism-Based Liabilities

Tong Li, Hongjin Wen, Cory Brayton, Fiona M. Laird, Guojun Ma, Shiwen Peng, Lisa Placanica, T. C. Wu, Barbara J. Crain, Donald L. Price, Charles G. Eberhart, Philip C. Wong

J Neurosci. 2007 Oct 3; 27(40): 10849–10859. doi: 10.1523/JNEUROSCI.2152-07.2007

PMCID:: PMC6672827

Abstract Article PDF–665K

Select item 45683063.

An atomic structure of human γ-secretase

Xiao-chen Bai, Chuangye Yan, Guanghui Yang, Peilong Lu, Dan Ma, Linfeng Sun, Rui Zhou, Sjors H.W. Scheres, Yigong Shi

Nature. Author manuscript; available in PMC 2016 Mar 10.

Published in final edited form as: Nature. 2015 Sep 10; 525(7568): 212–217. Published online 2015 Aug 17. doi: 10.1038/nature14892

PMCID:: PMC4568306

Abstract Article PDF–6.7M

Select item 41343234.

Three-dimensional structure of human γ-secretase

Peilong Lu, Xiao-chen Bai, Dan Ma, Tian Xie, Chuangye Yan, Linfeng Sun, Guanghui Yang, Yanyu Zhao, Rui Zhou, Sjors H.W. Scheres, Yigong Shi

Nature. Author manuscript; available in PMC 2015 Feb 14.

Published in final edited form as: Nature. 2014 Aug 14; 512(7513): 166–170. Published online 2014 Jun 29. doi: 10.1038/nature13567

PMCID:: PMC4134323

Abstract Article PDF–2.6M

Select item 31780595.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 28570166.

Aph-1 Associates Directly with Full-length and C-terminal Fragments of γ-Secretase Substrates

Allen C. Chen, Lucie Y. Guo, Beth L. Ostaszewski, Dennis J. Selkoe, Matthew J. LaVoie

J Biol Chem. 2010 Apr 9; 285(15): 11378–11391. Published online 2010 Feb 9. doi: 10.1074/jbc.M109.088815

PMCID:: PMC2857016

Abstract Article PDF–4.3M

Select item 28539427.

γ-Secretase Composed of PS1/Pen2/Aph1a Can Cleave Notch and Amyloid Precursor Protein in the Absence of Nicastrin

Guojun Zhao, Zhenyi Liu, Ma. Xenia G. Ilagan, Raphael Kopan

J Neurosci. 2010 Feb 3; 30(5): 1648–1656. doi: 10.1523/JNEUROSCI.3826-09.2010

PMCID:: PMC2853942

Abstract Article PDF–2.6M

Select item 28125138.

Synaptic and Endosomal Localization of Active γ-Secretase in Rat Brain

Susanne Frykman, Ji-Yeun Hur, Jenny Frånberg, Mikio Aoki, Bengt Winblad, Jarmila Nahalkova, Homira Behbahani, Lars O. Tjernberg

PLoS One. 2010; 5(1): e8948. Published online 2010 Jan 28. doi: 10.1371/journal.pone.0008948

PMCID:: PMC2812513

Abstract Article PDF–1.6M

Select item 1392419.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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