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Items: 1 to 20 of 61

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development
James F. Clark, Philippe Soriano
Biol Open. 2023 Jul 15; 12(7): bio059942. Published online 2023 Jul 27. doi: 10.1242/bio.059942
PMCID:
PMC10399203
AbstractArticlePDF–6.3M
3.
Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality
Jui-Yen Huang, Bruna Baumgarten Krebs, Marisha Lynn Miskus, May Lin Russell, Eamonn Patrick Duffy, Jason Michael Graf, Hui-Chen Lu
Sci Rep. 2020; 10: 18508. Published online 2020 Oct 28. doi: 10.1038/s41598-020-75537-0
PMCID:
PMC7595096
AbstractArticlePDF–17M
4.
Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development
Seth D. Kasowitz, Jun Ma, Stephen J. Anderson, N. Adrian Leu, Yang Xu, Brian D. Gregory, Richard M. Schultz, P. Jeremy Wang
PLoS Genet. 2018 May; 14(5): e1007412. Published online 2018 May 25. doi: 10.1371/journal.pgen.1007412
PMCID:
PMC5991768
AbstractArticlePDF–19M
5.
Crk proteins transduce FGF signaling to promote lens fiber cell elongation
Tamica N Collins, Yingyu Mao, Hongge Li, Michael Bouaziz, Angela Hong, Gen-Sheng Feng, Fen Wang, Lawrence A Quilliam, Lin Chen, Taeju Park, Tom Curran, Xin Zhang
eLife. 2018; 7: e32586. Published online 2018 Jan 23. doi: 10.7554/eLife.32586
PMCID:
PMC5818251
AbstractArticlePDF–8.2M
6.
Neurotrophin and FGF signaling adapter proteins, FRS2 and FRS3, regulate dentate granule cell maturation and excitatory synaptogenesis
Sayan Nandi, Karina Alviña, Pablo J. Lituma, Pablo E. Castillo, Jean M. Hébert
Neuroscience. Author manuscript; available in PMC 2019 Jan 15.
Published in final edited form as: Neuroscience. 2018 Jan 15; 369: 192–201. Published online 2017 Nov 16. doi: 10.1016/j.neuroscience.2017.11.017
PMCID:
PMC5766409
AbstractArticlePDF–4.1M
7.
Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease
Pawan Puri, Caitlin M. Schaefer, Daniel Bushnell, Mary E. Taglienti, Jordan A. Kreidberg, Bradley K. Yoder, Carlton M. Bates
Am J Pathol. 2018 Jan; 188(1): 84–94. doi: 10.1016/j.ajpath.2017.09.015
PMCID:
PMC5745541
AbstractArticlePDF–3.3M
8.
Loss of peri-Wolffian duct stromal Frs2a expression in mice leads to abnormal ureteric bud induction and vesicoureteral reflux
Deepti Narla, Stacey B. Slagle, Caitlin M. Schaefer, Daniel S. Bushnell, Pawan Puri, Carlton M. Bates
Pediatr Res. Author manuscript; available in PMC 2018 Feb 9.
Published in final edited form as: Pediatr Res. 2017 Dec; 82(6): 1022–1029. Published online 2017 Aug 9. doi: 10.1038/pr.2017.175
PMCID:
PMC5701656
AbstractArticlePDF–861K
9.
Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis
Ankur Garg, Mukesh Bansal, Noriko Gotoh, Gen-Sheng Feng, Jian Zhong, Fen Wang, Ariana Kariminejad, Steven Brooks, Xin Zhang
PLoS Genet. 2017 Oct; 13(10): e1007047. Published online 2017 Oct 13. doi: 10.1371/journal.pgen.1007047
PMCID:
PMC5656309
AbstractArticlePDF–30M
10.
FGF-Dependent, Context-Driven Role for FRS Adapters in the Early Telencephalon
Sayan Nandi, Grigoriy Gutin, Christopher A. Blackwood, Nachiket G. Kamatkar, Kyung W. Lee, Gordon Fishell, Fen Wang, Mitchell Goldfarb, Jean M. Hébert
J Neurosci. 2017 Jun 7; 37(23): 5690–5698. doi: 10.1523/JNEUROSCI.2931-16.2017
PMCID:
PMC5469306
AbstractArticlePDF–4.7M
11.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
12.
β1-integrin controls cell fate specification in early lens development
Mallika Pathania, Yan Wang, Vladimir N. Simirskii, Melinda K. Duncan
Differentiation. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Differentiation. 2016 Oct-Nov; 92(4): 133–147. Published online 2016 Sep 3. doi: 10.1016/j.diff.2016.08.002
PMCID:
PMC5159248
AbstractArticlePDF–2.8M
13.
Targeting of Ras-mediated FGF signaling suppresses Pten-deficient skin tumor
Grinu Mathew, Abdul Hannan, Kristina Hertzler-Schaefer, Fen Wang, Gen-Sheng Feng, Jian Zhong, Jean J. Zhao, Julian Downward, Xin Zhang
Proc Natl Acad Sci U S A. 2016 Nov 15; 113(46): 13156–13161. Published online 2016 Oct 31. doi: 10.1073/pnas.1604450113
PMCID:
PMC5135310
AbstractArticlePDF–2.1M
14.
Six2creFrs2α knockout mice are a novel model of renal cystogenesis
Pawan Puri, Daniel Bushnell, Caitlin M. Schaefer, Carlton M. Bates
Sci Rep. 2016; 6: 36736. Published online 2016 Nov 17. doi: 10.1038/srep36736
PMCID:
PMC5113122
AbstractArticlePDF–2.7M
15.
Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGFβ)-dependent smooth muscle cell phenotype modulation
Pei-Yu Chen, Lingfeng Qin, Guangxin Li, George Tellides, Michael Simons
Sci Rep. 2016; 6: 33407. Published online 2016 Sep 16. doi: 10.1038/srep33407
PMCID:
PMC5025753
AbstractArticlePDF–1.6M
16.
Hepatocyte FRS2α is Essential for the Endocrine Fibroblast Growth Factor to Limit the Amplitude of Bile Acid Production Induced by Prandial Activity
Cong Wang, Chaofeng Yang, Julia YF Chang, Pan You, Yue Li, Chengliu Jin, Yongde Luo, Xiaokun Li, Wallace L. McKeehan, Fen Wang
Curr Mol Med. Author manuscript; available in PMC 2016 Feb 26.
Published in final edited form as: Curr Mol Med. 2014; 14(6): 703–711. doi: 10.2174/1566524014666140724095112
PMCID:
PMC4768716
AbstractArticlePDF–1.3M
17.
Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells
Leena Paul, Emily M. Walker, Yiannis Drosos, Holly A. Cyphert, Geoffrey Neale, Roland Stein, Jack South, Gerard Grosveld, Pedro L. Herrera, Beatriz Sosa-Pineda
Diabetes. 2016 Mar; 65(3): 687–698. Published online 2015 Dec 2. doi: 10.2337/db15-0713
PMCID:
PMC4764148
AbstractArticlePDF–2.3M
18.
Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease
Brynn N. Akerberg, Maithri L. Sarangam, Kryn Stankunas
Dev Biol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: Dev Biol. 2015 Nov 1; 407(1): 158–172. Published online 2015 Jun 20. doi: 10.1016/j.ydbio.2015.06.015
PMCID:
PMC4694578
AbstractArticlePDF–4.8M
19.
Endothelial-to-mesenchymal transition drives atherosclerosis progression
Pei-Yu Chen, Lingfeng Qin, Nicolas Baeyens, Guangxin Li, Titilayo Afolabi, Madhusudhan Budatha, George Tellides, Martin A. Schwartz, Michael Simons
J Clin Invest. 2015 Dec 1; 125(12): 4514–4528. Published online 2015 Oct 26. doi: 10.1172/JCI82719
PMCID:
PMC4665771
AbstractArticlePDF–4.3M
20.
Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment
Yanqing Huang, Tomoaki Hamana, Junchen Liu, Cong Wang, Lei An, Pan You, Julia Y. F. Chang, Jianming Xu, Chengliu Jin, Zhongying Zhang, Wallace L. McKeehan, Fen Wang
J Biol Chem. 2015 Jul 17; 290(29): 17753–17761. Published online 2015 Jun 1. doi: 10.1074/jbc.M115.661066
PMCID:
PMC4505024
AbstractArticlePDF–2.1M

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