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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96874552.

Maternal Calorie Restriction Induces a Transcriptional Cytoprotective Response in Embryonic Liver Partially Dependent on Nrf2

George I. Habeos, Fotini Filippopoulou, Evagelia E. Habeos, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, George Lagoumintzis, Athanasios Niarchos, Christos D. Georgiou, Dionysios V. Chartoumpekis

Antioxidants (Basel) 2022 Nov; 11(11): 2274. Published online 2022 Nov 17. doi: 10.3390/antiox11112274

PMCID:: PMC9687455

Abstract Article PDF–2.0M

Select item 96193383.

Glutathione S-transferase Alpha 4 Induction by Activator Protein 1 in Colorectal Cancer

Yonghong Yang, Mark M. Huycke, Terence S. Herman, Xingmin Wang

Oncogene. Author manuscript; available in PMC 2022 Oct 31.

Published in final edited form as: Oncogene. 2016 Nov 3; 35(44): 5795–5806. Published online 2016 Apr 11. doi: 10.1038/onc.2016.113

PMCID:: PMC9619338

Abstract Article PDF–3.2M

Select item 96038604.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 70625626.

Effects of Gsta4 Deficiency on Age-related Cochlear Pathology and Hearing Loss in Mice

Hyo-Jin Park, Mi-Jung Kim, Chul Han, Karessa White, Dalian Ding, Kevin Boyd, Richard Salvi, Shinichi Someya

Exp Gerontol. Author manuscript; available in PMC 2021 May 1.

Published in final edited form as: Exp Gerontol. 2020 May; 133: 110872. Published online 2020 Feb 7. doi: 10.1016/j.exger.2020.110872

PMCID:: PMC7062562

Abstract Article PDF–2.0M

Select item 67426437.

GSTA4 mediates reduction of cisplatin ototoxicity in female mice

Hyo-Jin Park, Mi-Jung Kim, Christina Rothenberger, Ashok Kumar, Edith M. Sampson, Dalian Ding, Chul Han, Karessa White, Kevin Boyd, Senthilvelan Manohar, Yong-Hwan Kim, Maria S. Ticsa, Aaron S. Gomez, Isabela Caicedo, Upal Bose, Paul J. Linser, Takuya Miyakawa, Masaru Tanokura, Thomas C. Foster, Richard Salvi, Shinichi Someya

Nat Commun. 2019; 10: 4150. Published online 2019 Sep 12. doi: 10.1038/s41467-019-12073-0

PMCID:: PMC6742643

Abstract Article PDF–2.3M

Select item 60282968.

Knock-out of the Gsta4 gene in male mice leads to an altered pattern of hepatic protein carbonylation and enhanced inflammation following chronic consumption of an ethanol diet

Colin T. Shearn, Casey F. Pulliam, Kim Pedersen, Kyle Meredith, Kelly E. Mercer, Laura M. Saba, David J. Orlicky, Martin J. Ronis, Dennis R. Petersen

Alcohol Clin Exp Res. Author manuscript; available in PMC 2019 Jul 1.

Published in final edited form as: Alcohol Clin Exp Res. 2018 Jul; 42(7): 1192–1205. Published online 2018 May 30. doi: 10.1111/acer.13766

PMCID:: PMC6028296

Abstract Article PDF–1.0M

Select item 58461639.

An N-terminal motif unique to primate tau enables differential protein–protein interactions

Kristie Stefanoska, Alexander Volkerling, Josefine Bertz, Anne Poljak, Yazi D. Ke, Lars M. Ittner, Arne Ittner

J Biol Chem. 2018 Mar 9; 293(10): 3710–3719. Published online 2018 Jan 30. doi: 10.1074/jbc.RA118.001784

PMCID:: PMC5846163

Abstract Article PDF–1.2M

Select item 579108510.

Reduced Expression of Glutathione S-Transferase α4 Promotes Vascular Neointimal Hyperplasia in CKD

Jinlong Luo, Guang Chen, Ming Liang, Aini Xie, Qingtian Li, Qunying Guo, Rajendra Sharma, Jizhong Cheng

J Am Soc Nephrol. 2018 Feb; 29(2): 505–517. Published online 2017 Nov 10. doi: 10.1681/ASN.2017030290

PMCID:: PMC5791085

Abstract Article

Select item 538936211.

Global Deletion of Glutathione S-Transferase A4 Exacerbates Developmental Nonalcoholic Steatohepatitis

Martin Ronis, Kelly Mercer, Bridgette Engi, Casey Pulliam, Piotr Zimniak, Leah Hennings, Colin Shearn, Thomas Badger, Dennis Petersen

Am J Pathol. 2017 Feb; 187(2): 418–430. doi: 10.1016/j.ajpath.2016.10.022

PMCID:: PMC5389362

Abstract Article PDF–2.7M

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 487361813.

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Arash Yavari, Claire J. Stocker, Sahar Ghaffari, Edward T. Wargent, Violetta Steeples, Gabor Czibik, Katalin Pinter, Mohamed Bellahcene, Angela Woods, Pablo B. Martínez de Morentin, Céline Cansell, Brian Y.H. Lam, André Chuster, Kasparas Petkevicius, Marie-Sophie Nguyen-Tu, Aida Martinez-Sanchez, Timothy J. Pullen, Peter L. Oliver, Alexander Stockenhuber, Chinh Nguyen, Merzaka Lazdam, Jacqueline F. O’Dowd, Parvathy Harikumar, Mónika Tóth, Craig Beall, Theodosios Kyriakou, Julia Parnis, Dhruv Sarma, George Katritsis, Diana D.J. Wortmann, Andrew R. Harper, Laurence A. Brown, Robin Willows, Silvia Gandra, Victor Poncio, Márcio J. de Oliveira Figueiredo, Nathan R. Qi, Stuart N. Peirson, Rory J. McCrimmon, Balázs Gereben, László Tretter, Csaba Fekete, Charles Redwood, Giles S.H. Yeo, Lora K. Heisler, Guy A. Rutter, Mark A. Smith, Dominic J. Withers, David Carling, Eduardo B. Sternick, Jonathan R.S. Arch, Michael A. Cawthorne, Hugh Watkins, Houman Ashrafian

Cell Metab. 2016 May 10; 23(5): 821–836. doi: 10.1016/j.cmet.2016.04.003

PMCID:: PMC4873618

Abstract Article

Select item 468803714.

Effects of Local Heart Irradiation in a Glutathione S-Transferase Alpha 4-Null Mouse Model

Marjan Boerma, Preeti Singh, Vijayalakshmi Sridharan, Preeti Tripathi, Sunil Sharma, Sharda P. Singh

Radiat Res. Author manuscript; available in PMC 2015 Dec 22.

Published in final edited form as: Radiat Res. 2015 Jun; 183(6): 610–619. Published online 2015 May 26. doi: 10.1667/RR13979.1

PMCID:: PMC4688037

Abstract Article PDF–532K

Select item 468345915.

Deletion of GSTA4-4 results in increased mitochondrial post-translational modification of proteins by reactive aldehydes following chronic ethanol consumption in mice

Colin T. Shearn, Kristofer S. Fritz, Alisabeth H. Shearn, Laura M. Saba, Kelly E. Mercer, Bridgette Engi, James J. Galligan, Piotr Zimniak, David J. Orlicky, Martin J. Ronis, Dennis R. Petersen

Redox Biol. 2016 Apr; 7: 68–77. Published online 2015 Nov 27. doi: 10.1016/j.redox.2015.11.013

PMCID:: PMC4683459

Abstract Article PDF–8.4M

Select item 434675016.

Increased 4-hydroxynonenal protein adducts in male GSTA4–4/PPAR-α double knockout mice enhance injury during early stages of alcoholic liver disease

Martin J. J. Ronis, Kelly E. Mercer, Brenda Gannon, Bridgette Engi, Piotr Zimniak, Colin T. Shearn, David J. Orlicky, Emanuele Albano, Thomas M. Badger, Dennis R. Petersen

Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1; 308(5): G403–G415. Published online 2014 Dec 11. doi: 10.1152/ajpgi.00154.2014