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Items: 1 to 20 of 35

1.
Loss-of-function variants in SAT1 cause X-linked Childhood-onset Systemic Lupus Erythematosus
Lingxiao Xu, Jian Zhao, Qing Sun, Xue Xu, Lei Wang, Ting Liu, Yunjuan Wu, Jingfeng Zhu, Linyu Geng, Yun Deng, Alexander Awgulewitsch, Diane L. Kamen, Jim C. Oates, Prithvi Raj, Edward K. Wakeland, R. Hal Scofield, Joel M. Guthridge, Judith A. James, Bevra H Hahn, Deborah K. McCurdy, Fang Wang, Miaojia Zhang, Wenfeng Tan, Gary S. Gilkeson, Betty P. Tsao
Ann Rheum Dis. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Ann Rheum Dis. 2022 Dec; 81(12): 1712–1721. Published online 2022 Aug 17. doi: 10.1136/ard-2022-222795
PMCID:
PMC10394691
AbstractArticlePDF–1.8M
2.
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex
Tamar Sapir, Aditya Kshirsagar, Anna Gorelik, Tsviya Olender, Ziv Porat, Ingrid E. Scheffer, David B. Goldstein, Orrin Devinsky, Orly Reiner
Nat Commun. 2022; 13: 4209. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31752-z
PMCID:
PMC9304408
AbstractArticlePDF–13M
3.
Metabolic Modeling of Single Th17 Cells Reveals Regulators of Autoimmunity
Allon Wagner, Chao Wang, Johannes Fessler, David DeTomaso, Julian Avila-Pacheco, James Kaminski, Sarah Zaghouani, Elena Christian, Pratiksha Thakore, Brandon Schellhaass, Elliot Akama-Garren, Kerry Pierce, Vasundhara Singh, Noga Ron-Harel, Vivian Paraskevi Douglas, Lloyd Bod, Alexandra Schnell, Daniel Puleston, Raymond A. Sobel, Marcia Haigis, Erika Pearce, Manoocher Soleimani, Clary Clish, Aviv Regev, Vijay K. Kuchroo, Nir Yosef
Cell. Author manuscript; available in PMC 2022 Aug 5.
Published in final edited form as: Cell. 2021 Aug 5; 184(16): 4168–4185.e21. Published online 2021 Jul 2. doi: 10.1016/j.cell.2021.05.045
PMCID:
PMC8621950
AbstractArticlePDF–3.5M
4.
Ablation of polyamine catabolic enzymes provokes Purkinje cell damage, neuroinflammation, and severe ataxia
Kamyar Zahedi, Marybeth Brooks, Sharon Barone, Negah Rahmati, Tracy Murray Stewart, Matthew Dunworth, Christina Destefano-Shields, Nupur Dasgupta, Steve Davidson, Diana M. Lindquist, Christine E. Fuller, Roger D. Smith, John L. Cleveland, Robert A. Casero, Jr, Manoocher Soleimani
J Neuroinflammation. 2020; 17: 301. Published online 2020 Oct 14. doi: 10.1186/s12974-020-01955-6
PMCID:
PMC7559641
AbstractArticlePDF–12M
5.
Spermidine/spermine N1-acetyltransferase-mediated polyamine catabolism regulates beige adipocyte biogenesis
Fang Yuan, Lin Zhang, Yang Cao, Wei Gao, Can Zhao, Yuan Fang, Kamyar Zahedi, Manoocher Soleimani, Xiang Lu, Zhuyuan Fang, Qin Yang
Metabolism. Author manuscript; available in PMC 2020 Jun 3.
Published in final edited form as: Metabolism. 2018 Aug; 85: 298–304. Published online 2018 Apr 30. doi: 10.1016/j.metabol.2018.04.007
PMCID:
PMC7269456
AbstractArticlePDF–1.2M
6.
Activation of endoplasmic reticulum stress response by enhanced polyamine catabolism is important in the mediation of cisplatin-induced acute kidney injury
Kamyar Zahedi, Sharon Barone, Christina Destefano-Shields, Marybeth Brooks, Tracy Murray-Stewart, Matthew Dunworth, Weimin Li, Joanne R. Doherty, Mark A. Hall, Roger D. Smith, John L. Cleveland, Robert A. Casero, Jr., Manoocher Soleimani
PLoS One. 2017; 12(9): e0184570. Published online 2017 Sep 8. doi: 10.1371/journal.pone.0184570
PMCID:
PMC5590979
AbstractArticlePDF–11M
7.
Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia
Xin Heng, Qiuxia Guo, Alan W Leung, James YH Li
eLife. 2017; 6: e23253. Published online 2017 May 10. doi: 10.7554/eLife.23253
PMCID:
PMC5457141
AbstractArticlePDF–11M
8.
Modulation of polyamine metabolic flux in adipose tissue alters the accumulation of body fat by affecting glucose homeostasis
Chunli Liu, Oscar Perez-Leal, Carlos Barrero, Kamyar Zahedi, Manoocher Soleimani, Carl Porter, Salim Merali
Amino Acids. Author manuscript; available in PMC 2016 Dec 26.
Published in final edited form as: Amino Acids. 2014 Mar; 46(3): 701–715. Published online 2013 Jul 24. doi: 10.1007/s00726-013-1548-3
PMCID:
PMC5184767
AbstractArticlePDF–735K
9.
Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses
Yang Ou, Shang-Jui Wang, Dawei Li, Bo Chu, Wei Gu
Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): E6806–E6812. Published online 2016 Oct 3. doi: 10.1073/pnas.1607152113
PMCID:
PMC5098629
AbstractArticlePDF–1.3M
10.
Proximal Tubule Epithelial Cell Specific Ablation of the Spermidine/Spermine N1-Acetyltransferase Gene Reduces the Severity of Renal Ischemia/Reperfusion Injury
Kamyar Zahedi, Sharon Barone, Yang Wang, Tracy Murray-Stewart, Prabir Roy-Chaudhury, Roger D. Smith, Robert A. Casero, Jr, Manoocher Soleimani
PLoS One. 2014; 9(11): e110161. Published online 2014 Nov 12. doi: 10.1371/journal.pone.0110161
PMCID:
PMC4229091
AbstractArticlePDF–2.6M
11.
Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts
Anne Uimari, Tuomo A. KEINäNEN, Anne Karppinen, Patrick Woster, Pekka UIMARI Alhonen, Juhani JäNNE, Leena Alhonen
Biochem J. Author manuscript; available in PMC 2014 Sep 29.
Published in final edited form as: Biochem J. 2009 Aug 15; 422(1): 101–109. Published online 2009 Jul 29. doi: 10.1042/BJ20090411
PMCID:
PMC4180119
AbstractArticlePDF–1.1M
12.
Hyperoxaluric rats do not exhibit alterations in renal expression patterns of Slc26a1 (SAT1) mRNA or protein
Robert W. Freel, Marguerite Hatch
Urol Res. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Urol Res. 2012 Dec; 40(6): 647–654. Published online 2012 May 10. doi: 10.1007/s00240-012-0480-4
PMCID:
PMC3708603
AbstractArticlePDF–1.7M
13.
Hepatocyte-specific ablation of spermine/spermidine-N1-acetyltransferase gene reduces the severity of CCl4-induced acute liver injury
Kamyar Zahedi, Sharon L. Barone, Jie Xu, Nora Steinbergs, Rebecca Schuster, Alex B. Lentsch, Hassane Amlal, Jiang Wang, Robert A. Casero, Jr, Manoocher Soleimani
Am J Physiol Gastrointest Liver Physiol. 2012 Sep 1; 303(5): G546–G560. Published online 2012 Jun 18. doi: 10.1152/ajpgi.00431.2011
PMCID:
PMC3468550
AbstractArticle
14.
Complex N-Acetylation of Triethylenetetramine
Marc Cerrada-Gimenez, Janne Weisell, Mervi T. Hyvönen, Myung Hee Park, Leena Alhonen, Jouko Vepsäläinen, Tuomo A. Keinänen
Drug Metab Dispos. 2011 Dec; 39(12): 2242–2249. doi: 10.1124/dmd.111.041798
PMCID:
PMC3226374
AbstractArticlePDF–1.0M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
17.
Polyamine pathway contributes to the pathogenesis of Parkinson disease
Nicole M. Lewandowski, Shulin Ju, Miguel Verbitsky, Barbara Ross, Melissa L. Geddie, Edward Rockenstein, Anthony Adame, Alim Muhammad, Jean Paul Vonsattel, Dagmar Ringe, Lucien Cote, Susan Lindquist, Eliezer Masliah, Gregory A. Petsko, Karen Marder, Lorraine N. Clark, Scott A. Small
Proc Natl Acad Sci U S A. 2010 Sep 28; 107(39): 16970–16975. Published online 2010 Sep 13. doi: 10.1073/pnas.1011751107
PMCID:
PMC2947879
AbstractArticlePDF–773K
18.
UPF2 Is a Critical Regulator of Liver Development, Function and Regeneration
Lina A. Thoren, Gitte A. Nørgaard, Joachim Weischenfeldt, Johannes Waage, Janus S. Jakobsen, Inge Damgaard, Frida C. Bergström, Anna M. Blom, Rehannah Borup, Hanne Cathrine Bisgaard, Bo T. Porse
PLoS One. 2010; 5(7): e11650. Published online 2010 Jul 19. doi: 10.1371/journal.pone.0011650
PMCID:
PMC2906512
AbstractArticlePDF–10M
19.
The role of spermidine/spermine N1-acetyltransferase in endotoxin-induced acute kidney injury
Kamyar Zahedi, Sharon Barone, Debora L. Kramer, Hassane Amlal, Leena Alhonen, Juhani Jänne, Carl W. Porter, Manoocher Soleimani
Am J Physiol Cell Physiol. 2010 Jul; 299(1): C164–C174. Published online 2010 Apr 14. doi: 10.1152/ajpcell.00512.2009
PMCID:
PMC2904252
AbstractArticle
20.
Urolithiasis and hepatotoxicity are linked to the anion transporter Sat1 in mice
Paul A. Dawson, Christopher S. Russell, Soohyun Lee, Sarah C. McLeay, Jacobus M. van Dongen, David M. Cowley, Lorne A. Clarke, Daniel Markovich
J Clin Invest. 2010 Mar 1; 120(3): 706–712. Published online 2010 Feb 15. doi: 10.1172/JCI31474
PMCID:
PMC2827940
AbstractArticlePDF–2.0M

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