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Select item 115737931.

Transgenic sensors reveal compartment-specific effects of aggregation-prone proteins on subcellular proteostasis during aging

Michelle Curley, Mamta Rai, Chia-Lung Chuang, Vishwajeeth Pagala, Anna Stephan, Zane Coleman, Maricela Robles-Murguia, Yong-Dong Wang, Junmin Peng, Fabio Demontis

Cell Rep Methods. 2024 Oct 21; 4(10): 100875. Published online 2024 Oct 8. doi: 10.1016/j.crmeth.2024.100875

PMCID:: PMC11573793

Abstract Article PDF–9.3M

Select item 114888442.

Heat stress proteins and transcription factors

L. Nover, K.-D. Scharf

Cell Mol Life Sci. 1997 Jan; 53(1): 80–103. Published online 2024 Aug 31. doi: 10.1007/PL00000583

PMCID:: PMC11488844

Abstract PDF–471K

Select item 113798823.

Two novel DnaJ chaperone proteins CG5001 and P58IPK regulate the pathogenicity of Huntington’s disease related aggregates

Ankita Deo, Rishita Ghosh, Snehal Ahire, Sayali Marathe, Amitabha Majumdar, Tania Bose

Sci Rep. 2024; 14: 20867. Published online 2024 Sep 6. doi: 10.1038/s41598-024-71065-3

PMCID:: PMC11379882

Abstract Article PDF–7.3M

Select item 109077004.

Baf-mediated transcriptional regulation of teashirt is essential for the development of neural progenitor cell lineages

Byung Su Ko, Myeong Hoon Han, Min Jee Kwon, Dong Gon Cha, Yuri Ji, Eun Seo Park, Min Jae Jeon, Somi Kim, Kyeongho Lee, Yoon Ha Choi, Jusung Lee, Monica Torras-Llort, Ki-Jun Yoon, Hyosang Lee, Jong Kyoung Kim, Sung Bae Lee

Exp Mol Med. 2024 Feb; 56(2): 422–440. Published online 2024 Feb 19. doi: 10.1038/s12276-024-01169-3

PMCID:: PMC10907700

Abstract Article PDF–7.5M

Select item 108919755.

Exposure to the Natural Compound Climacostol Induces Cell Damage and Oxidative Stress in the Fruit Fly Drosophila melanogaster

Elisabetta Catalani, Kashi Brunetti, Simona Del Quondam, Silvia Bongiorni, Simona Picchietti, Anna Maria Fausto, Gabriele Lupidi, Enrico Marcantoni, Cristiana Perrotta, Gabriele Achille, Federico Buonanno, Claudio Ortenzi, Davide Cervia

Toxics. 2024 Feb; 12(2): 102. Published online 2024 Jan 24. doi: 10.3390/toxics12020102

PMCID:: PMC10891975

Abstract Article PDF–6.2M

Select item 108162826.

The Lifespan of D. melanogaster Depends on the Function of the Gagr Gene, a Domesticated gag Gene of Drosophila LTR Retrotransposons

Yevgenia Balakireva, Maria Nikitina, Pavel Makhnovskii, Inna Kukushkina, Ilya Kuzmin, Alexander Kim, Lidia Nefedova

Insects. 2024 Jan; 15(1): 68. Published online 2024 Jan 17. doi: 10.3390/insects15010068

PMCID:: PMC10816282

Abstract Article PDF–4.1M

Select item 102641577.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 100857568.

Polycomb response elements reduce leaky expression of Cas9 under temperature-inducible Hsp70Bb promoter in Drosophila melanogaster

Natalie Warsinger-Pepe, Carly Chang, Connor R Desroberts, Omar S Akbari

G3 (Bethesda) 2023 Apr; 13(4): jkad024. Published online 2023 Jan 27. doi: 10.1093/g3journal/jkad024

PMCID:: PMC10085756

Abstract Article PDF–1.4M

Select item 100789179.

A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi

William W Fisher, Ann S Hammonds, Richard Weiszmann, Benjamin W Booth, Louis Gevirtzman, Jaeda E J Patton, Connor A Kubo, Robert H Waterston, Susan E Celniker

Genetics. 2023 Apr; 223(4): iyad004. Published online 2023 Jan 19. doi: 10.1093/genetics/iyad004

PMCID:: PMC10078917

Abstract Article PDF–18M

Select item 947454510.

Mettl3-dependent m⁶A modification attenuates the brain stress response in Drosophila

Alexandra E. Perlegos, Emily J. Shields, Hui Shen, Kathy Fange Liu, Nancy M. Bonini

Nat Commun. 2022; 13: 5387. Published online 2022 Sep 14. doi: 10.1038/s41467-022-33085-3

PMCID:: PMC9474545

Abstract Article PDF–2.7M

Select item 945842111.

The DEAD-box helicase Hlc regulates basal transcription and chromatin opening of stress-responsive genes

Ruirui Jia, Jiamei Lin, Jin You, Shi Li, Ge Shan, Chuan Huang

Nucleic Acids Res. 2022 Sep 9; 50(16): 9175–9189. Published online 2022 Aug 11. doi: 10.1093/nar/gkac684

PMCID:: PMC9458421

Abstract Article PDF–2.5M

Select item 935702212.

The CRTC-CREB axis functions as a transcriptional sensor to protect against proteotoxic stress in Drosophila

Youjie Yin, Peng Ma, Saifei Wang, Yao Zhang, Ruolei Han, Chunyu Huo, Meixian Wu, Hansong Deng

Cell Death Dis. 2022 Aug; 13(8): 688. Published online 2022 Aug 6. doi: 10.1038/s41419-022-05122-y

PMCID:: PMC9357022

Abstract Article PDF–4.5M

Select item 928742613.

Fatty acid tryptamide from cacao elongates Drosophila melanogaster lifespan with sirtuin-dependent heat shock protein expression

Kiko Kanno, Yasunari Kayashima, Kazuji Tamura, Takako Miyara, Kento Baba, Megumi Koganei, Midori Natsume, Shinjiro Imai

Sci Rep. 2022; 12: 12080. Published online 2022 Jul 15. doi: 10.1038/s41598-022-16471-1

PMCID:: PMC9287426

Abstract Article PDF–2.1M

Select item 910052114.

Photoperiod-Dependent Expression of MicroRNA in Drosophila

Mirko Pegoraro, Bettina Fishman, Valeria Zonato, Georgios Zouganelis, Amanda Francis, Charalambos P. Kyriacou, Eran Tauber

Int J Mol Sci. 2022 May; 23(9): 4935. Published online 2022 Apr 29. doi: 10.3390/ijms23094935

PMCID:: PMC9100521

Abstract Article PDF–1.5M

Select item 901959515.

Phylogenetic annotation of Drosophila melanogaster heat shock protein 70 genes

Gen Kaneko

MicroPubl Biol. 2022; 2022: 10.17912/micropub.biology.000558. Published online 2022 Apr 20. doi: 10.17912/micropub.biology.000558

PMCID:: PMC9019595

Abstract Article PDF–517K

Select item 893368716.

Microbiome-by-ethanol interactions impact Drosophila melanogaster fitness, physiology, and behavior

James Angus Chandler, Lina Victoria Innocent, Daniel Jonathan Martinez, Isaac Li Huang, Jane Lani Yang, Michael Bruce Eisen, William Basil Ludington

iScience. 2022 Apr 15; 25(4): 104000. Published online 2022 Feb 28. doi: 10.1016/j.isci.2022.104000

PMCID:: PMC8933687

Abstract Article PDF–2.7M

Select item 874227117.

Temperature-Inducible Precision-Guided Sterile Insect Technique

Nikolay P. Kandul, Junru Liu, Omar S. Akbari

CRISPR J. December 2021; 4(6): 822–835. Published online 2021 Dec 16. doi: 10.1089/crispr.2021.0077

PMCID:: PMC8742271

Abstract Article PDF–1.2M

Select item 861049318.

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee

eLife. 2021; 10: e67516. Published online 2021 Oct 29. doi: 10.7554/eLife.67516

PMCID:: PMC8610493

Abstract Article PDF–13M

Select item 858467019.

A behavioral screen for mediators of age-dependent TDP-43 neurodegeneration identifies SF2/SRSF1 among a group of potent suppressors in both neurons and glia

Jorge Azpurua, Enas Gad El-Karim, Marvel Tranquille, Josh Dubnau

PLoS Genet. 2021 Nov; 17(11): e1009882. Published online 2021 Nov 1. doi: 10.1371/journal.pgen.1009882

PMCID:: PMC8584670

Abstract Article PDF–1.4M

Select item 849627720.

A cross-species approach for the identification of Drosophila male sterility genes

Kimihide Ibaraki, Mihoko Nakatsuka, Takashi Ohsako, Masahide Watanabe, Yu Miyazaki, Machi Shirakami, Timothy L Karr, Rikako Sanuki, Masatoshi Tomaru, Toshiyuki Takano-Shimizu-Kouno

G3 (Bethesda) 2021 Aug; 11(8): jkab183. Published online 2021 May 29. doi: 10.1093/g3journal/jkab183