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Select item 110324331.

Genetic mechanism regulating diversity in the placement of eyes on the head of animals

Oorvashi Roy Puli, Neha Gogia, Anuradha Venkatakrishnan Chimata, Takeshi Yorimitsu, Hideki Nakagoshi, Madhuri Kango-Singh, Amit Singh

Proc Natl Acad Sci U S A. 2024 Apr 16; 121(16): e2316244121. Published online 2024 Apr 8. doi: 10.1073/pnas.2316244121

PMCID:: PMC11032433

Abstract Article PDF–4.8M

Select item 110314052.

Inhibition of S6K lowers age-related inflammation and increases lifespan through the endolysosomal system

Pingze Zhang, James H. Catterson, Sebastian Grönke, Linda Partridge

Nat Aging. 2024; 4(4): 491–509. Published online 2024 Feb 27. doi: 10.1038/s43587-024-00578-3

PMCID:: PMC11031405

Abstract Article PDF–12M

Select item 108987353.

Endolysosomal trafficking controls yolk granule biogenesis in vitellogenic Drosophila oocytes

Yue Yu, Dongsheng Chen, Stephen M. Farmer, Shiyu Xu, Beatriz Rios, Amanda Solbach, Xin Ye, Lili Ye, Sheng Zhang

PLoS Genet. 2024 Feb; 20(2): e1011152. Published online 2024 Feb 5. doi: 10.1371/journal.pgen.1011152

PMCID:: PMC10898735

Abstract Article PDF–9.6M

Select item 108510224.

Oxidative Stress Contributes to Slit Diaphragm Defects Caused by Disruption of Endocytosis

Gang Xi, Sajan A. Lamba, Michael Mysh, John S. Poulton

Kidney Int Rep. 2024 Feb; 9(2): 451–463. Published online 2023 Nov 25. doi: 10.1016/j.ekir.2023.11.018

PMCID:: PMC10851022

Abstract Article PDF–3.2M

Select item 108477255.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 107654146.

APOL1-G2 accelerates nephrocyte cell death by inhibiting the autophagy pathway

Jun-yi Zhu, Jin-Gu Lee, Yulong Fu, Joyce van de Leemput, Patricio E. Ray, Zhe Han

Dis Model Mech. 2023 Dec 1; 16(12): dmm050223. Published online 2023 Dec 27. doi: 10.1242/dmm.050223

PMCID:: PMC10765414

Abstract Article

Select item 106627617.

Coordination of Pickpocket ion channel delivery and dendrite growth in Drosophila sensory neurons

Josephine W. Mitchell, Ipek Midillioglu, Ethan Schauer, Bei Wang, Chun Han, Jill Wildonger

PLoS Genet. 2023 Nov; 19(11): e1011025. Published online 2023 Nov 9. doi: 10.1371/journal.pgen.1011025

PMCID:: PMC10662761

Abstract Article PDF–5.6M

Select item 105847558.

Insights into human kidney function from the study of Drosophila

Sybille Koehler, Tobias B. Huber

Pediatr Nephrol. 2023; 38(12): 3875–3887. Published online 2023 May 12. doi: 10.1007/s00467-023-05996-w

PMCID:: PMC10584755

Abstract Article PDF–1.2M

Select item 105142029.

The TNFR Wengen regulates the FGF pathway by an unconventional mechanism

Annalisa Letizia, Maria Lluisa Espinàs, Panagiotis Giannios, Marta Llimargas

Nat Commun. 2023; 14: 5874. Published online 2023 Sep 21. doi: 10.1038/s41467-023-41549-3

PMCID:: PMC10514202

Abstract Article PDF–5.4M

Select item 1044580210.

A Rab39-Klp98A-Rab35 endocytic recycling pathway is essential for rapid Golgi-dependent furrow ingression

Hui Miao, Megan Millage, Katherine R. Rollins, J. Todd Blankenship

Development. 2023 Aug 15; 150(16): dev201547. Published online 2023 Aug 17. doi: 10.1242/dev.201547

PMCID:: PMC10445802

Abstract Article

Select item 1039888611.

Interaction of the sorting nexin 25 homologue Snazarus with Rab11 balances endocytic and secretory transport and maintains the ultrafiltration diaphragm in nephrocytes

Tamás Maruzs, Dalma Feil-Börcsök, Enikő Lakatos, Gábor Juhász, András Blastyák, Dávid Hargitai, Steve Jean, Péter Lőrincz, Gábor Juhász

Mol Biol Cell. 2023 Aug 1; 34(9): ar87. Published online 2023 Aug 1. doi: 10.1091/mbc.E22-09-0421

PMCID:: PMC10398886

Abstract Article PDF–2.7M

Select item 1038757612.

Role of Rab5 early endosomes in regulating Drosophila gut antibacterial response

Manish Joshi, Annelise Viallat-Lieutaud, Julien Royet

iScience. 2023 Aug 18; 26(8): 107335. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107335

PMCID:: PMC10387576

Abstract Article PDF–6.7M

Select item 1037257613.

Regulatory sites in the Mon1–Ccz1 complex control Rab5 to Rab7 transition and endosome maturation

Ann-Christin Borchers, Maren Janz, Jan-Hannes Schäfer, Arne Moeller, Daniel Kümmel, Achim Paululat, Christian Ungermann, Lars Langemeyer

Proc Natl Acad Sci U S A. 2023 Jul 25; 120(30): e2303750120. Published online 2023 Jul 18. doi: 10.1073/pnas.2303750120

PMCID:: PMC10372576

Abstract Article PDF–2.0M

Select item 1031663014.

Gbb glutathionylation promotes its proteasome-mediated degradation to inhibit synapse growth

Md Shafayat Hossain, Aiyu Yao, Xinhua Qiao, Wenwen Shi, Ting Xie, Chang Chen, Yong Q. Zhang

J Cell Biol. 2023 Sep 4; 222(9): e202202068. Published online 2023 Jun 30. doi: 10.1083/jcb.202202068

PMCID:: PMC10316630

Abstract Article PDF–6.6M

Select item 1025504915.

Control of Synaptic Levels of Nicotinic Acetylcholine Receptor by the Sequestering Subunit Dα5 and Secreted Scaffold Protein Hig

Minoru Nakayama, Osamu Nishimura, Yuhi Nishimura, Miwa Kitaichi, Shigehiro Kuraku, Masaki Sone, Chihiro Hama

J Neurosci. 2023 May 31; 43(22): 3989–4004. doi: 10.1523/JNEUROSCI.2243-21.2023

PMCID:: PMC10255049

Abstract Article PDF–7.4M

Select item 1022708016.

LC3-associated phagocytosis promotes glial degradation of axon debris after injury in Drosophila models

Áron Szabó, Virág Vincze, Aishwarya Sanjay Chhatre, András Jipa, Sarolta Bognár, Katalin Eszter Varga, Poulami Banik, Adél Harmatos-Ürmösi, Lukas J. Neukomm, Gábor Juhász

Nat Commun. 2023; 14: 3077. Published online 2023 May 29. doi: 10.1038/s41467-023-38755-4

PMCID:: PMC10227080

Abstract Article PDF–9.4M

Select item 1017559117.

Chitinase-like proteins promoting tumorigenesis through disruption of cell polarity via enlarged endosomal vesicles

Dilan Khalili, Martin Kunc, Sarah Herbrich, Anna M. Müller, Ulrich Theopold

Front Oncol. 2023; 13: 1170122. Published online 2023 Apr 28. doi: 10.3389/fonc.2023.1170122

PMCID:: PMC10175591

Abstract Article PDF–14M

Select item 1014737818.

Axon guidance genes modulate neurotoxicity of ALS-associated UBQLN2

Sang Hwa Kim, Kye D Nichols, Eric N Anderson, Yining Liu, Nandini Ramesh, Weiyan Jia, Connor J Kuerbis, Mark Scalf, Lloyd M Smith, Udai Bhan Pandey, Randal S Tibbetts

eLife. 2023; 12: e84382. Published online 2023 Apr 11. doi: 10.7554/eLife.84382

PMCID:: PMC10147378

Abstract Article PDF–33M

Select item 1004117319.

Fragile X mental retardation protein coordinates neuron-to-glia communication for clearance of developmentally transient brain neurons

Chunzhu Song, Kendal Broadie

Proc Natl Acad Sci U S A. 2023 Mar 21; 120(12): e2216887120. Published online 2023 Mar 15. doi: 10.1073/pnas.2216887120

PMCID:: PMC10041173

Abstract Article PDF–2.8M

Select item 1001538020.

Phase separation of Hippo signalling complexes

Teresa T Bonello, Danfeng Cai, Georgina C Fletcher, Kyler Wiengartner, Victoria Pengilly, Kimberly S Lange, Zhe Liu, Jennifer Lippincott‐Schwartz, Jennifer M Kavran, Barry J Thompson

EMBO J. 2023 Mar; 42(6): e112863. Published online 2023 Feb 20. doi: 10.15252/embj.2022112863