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Select item 109455081.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700

PMCID:: PMC10945508

Abstract Article PDF–5.7M

Select item 109359542.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 109334773.

Drosophila eIF3f1 mediates host immune defense by targeting dTak1

Yixuan Hu, Fanrui Kong, Huimin Guo, Yongzhi Hua, Yangyang Zhu, Chuchu Zhang, Abdul Qadeer, Yihua Xiao, Qingshuang Cai, Shanming Ji

EMBO Rep. 2024 Mar; 25(3): 1415–1435. Published online 2024 Jan 26. doi: 10.1038/s44319-024-00067-z

PMCID:: PMC10933477

Abstract Article PDF–3.5M

Select item 107499474.

Markers and mechanisms of death in Drosophila

John Tower

Front Aging. 2023; 4: 1292040. Published online 2023 Dec 12. doi: 10.3389/fragi.2023.1292040

PMCID:: PMC10749947

Abstract Article PDF–1.4M

Select item 107326905.

A Drosophila melanogaster model shows that fast growing Metarhizium species are the deadliest despite eliciting a strong immune response

Jonathan B. Wang, Hsiao-Ling Lu, Huiyu Sheng, Raymond J St. Leger

Virulence. 2023; 14(1): 2275493. Published online 2023 Nov 8. doi: 10.1080/21505594.2023.2275493

PMCID:: PMC10732690

Abstract Article PDF–4.7M

Select item 107246946.

The adaptor protein 14-3-3zeta modulates intestinal immunity and aging in Drosophila

Xiaolan Fan, Tiantian Huang, Shuai Wang, Ziyue Yang, Wenhao Song, Yao Zeng, Yingdong Tong, Yujuan Cai, Deying Yang, Bo Zeng, Mingwang Zhang, Qingyong Ni, Yan Li, Diyan Li, Mingyao Yang

J Biol Chem. 2023 Dec; 299(12): 105414. Published online 2023 Oct 31. doi: 10.1016/j.jbc.2023.105414

PMCID:: PMC10724694

Abstract Article PDF–2.7M

Select item 106974167.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 106523108.

Smurfness‐based two‐phase model of ageing helps deconvolve the ageing transcriptional signature

Flaminia Zane, Hayet Bouzid, Sofia Sosa Marmol, Mira Brazane, Savandara Besse, Julia Lisa Molina, Céline Cansell, Fanny Aprahamian, Sylvère Durand, Jessica Ayache, Christophe Antoniewski, Nicolas Todd, Clément Carré, Michael Rera

Aging Cell. 2023 Nov; 22(11): e13946. Published online 2023 Oct 12. doi: 10.1111/acel.13946

PMCID:: PMC10652310

Abstract Article PDF–20M

Select item 106164859.

Interactions between innate immunity and insulin signaling affect resistance to infection in insects

Andrea M. Darby, Brian P. Lazzaro

Front Immunol. 2023; 14: 1276357. Published online 2023 Oct 17. doi: 10.3389/fimmu.2023.1276357

Correction in:: Front Immunol. 2024; 15: 1400514.

PMCID:: PMC10616485

Abstract Article PDF–1.5M

Select item 1060910710.

The Sterol Transporter Npc2c Controls Intestinal Stem Cell Mitosis and Host–Microbiome Interactions in Drosophila

Constantina Neophytou, Euripides Soteriou, Chrysoula Pitsouli

Metabolites. 2023 Oct; 13(10): 1084. Published online 2023 Oct 16. doi: 10.3390/metabo13101084

PMCID:: PMC10609107

Abstract Article PDF–8.3M

Select item 1059016111.

The reproductive status determines tolerance and resistance to Mycobacterium marinum in Drosophila melanogaster

Marta Arch, Maria Vidal, Esther Fuentes, Anmaw Shite Abat, Pere-Joan Cardona

Evol Med Public Health. 2023; 11(1): 332–347. Published online 2023 Sep 6. doi: 10.1093/emph/eoad029

PMCID:: PMC10590161

Abstract Article PDF–907K

Select item 1057756512.

Heterochromatic silencing of immune‐related genes in glia is required for BBB integrity and normal lifespan in drosophila

Shunpan Shu, Mingsheng Jiang, Xue Deng, Wenkai Yue, Xu Cao, Kai Zhang, Zeqing Wang, Hao He, Jihong Cui, Qiangqiang Wang, Kun Qu, Yanshan Fang

Aging Cell. 2023 Oct; 22(10): e13947. Published online 2023 Aug 18. doi: 10.1111/acel.13947

PMCID:: PMC10577565

Abstract Article PDF–12M

Select item 1056293413.

The nematode parasite Steinernema hermaphroditum is pathogenic to Drosophila melanogaster larvae without activating their immune response

Tien Huynh, Damien O'Halloran, John Hawdon, Ioannis Eleftherianos

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000944. Published online 2023 Sep 25. doi: 10.17912/micropub.biology.000944

PMCID:: PMC10562934

Abstract Article PDF–187K

Select item 1054721114.

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Kriti Gupta, Sveta Chakrabarti, Vishnu Janardan, Nishita Gogia, Sanghita Banerjee, Swarna Srinivas, Deepthi Mahishi, Sandhya S. Visweswariah

PLoS Genet. 2023 Sep; 19(9): e1010962. Published online 2023 Sep 21. doi: 10.1371/journal.pgen.1010962

PMCID:: PMC10547211

Abstract Article PDF–2.9M

Select item 1054606815.

Single-cell sequencing of tumor-associated macrophages in a Drosophila model

Dilan Khalili, Mubasher Mohammed, Martin Kunc, Martina Sindlerova, Johan Ankarklev, Ulrich Theopold

Front Immunol. 2023; 14: 1243797. Published online 2023 Sep 19. doi: 10.3389/fimmu.2023.1243797

PMCID:: PMC10546068

Abstract Article PDF–7.2M

Select item 1048312616.

Effect of aminergic signaling on the humoral innate immunity response of Drosophila

Giulia Cattabriga, Giorgia Giordani, Giuseppe Gargiulo, Valeria Cavaliere

Front Physiol. 2023; 14: 1249205. Published online 2023 Aug 24. doi: 10.3389/fphys.2023.1249205

PMCID:: PMC10483126

Abstract Article PDF–929K

Select item 1043400417.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 1031778418.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 1027036019.

Steroid hormone regulation of innate immunity in Drosophila melanogaster

Scott A. Keith

PLoS Genet. 2023 Jun; 19(6): e1010782. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010782

PMCID:: PMC10270360

Abstract Article PDF–1.0M

Select item 1027035120.

Damage sensing mediated by serine proteases Hayan and Persephone for Toll pathway activation in apoptosis-deficient flies

Shotaro Nakano, Soshiro Kashio, Kei Nishimura, Asuka Takeishi, Hina Kosakamoto, Fumiaki Obata, Erina Kuranaga, Takahiro Chihara, Yoshio Yamauchi, Toshiaki Isobe, Masayuki Miura

PLoS Genet. 2023 Jun; 19(6): e1010761. Published online 2023 Jun 15. doi: 10.1371/journal.pgen.1010761