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Items: 1 to 20 of 28

1.
Epi-microRNA mediated metabolic reprogramming counteracts hypoxia to preserve affinity maturation
Rinako Nakagawa, Miriam Llorian, Sunita Varsani-Brown, Probir Chakravarty, Jeannie M. Camarillo, David Barry, Roger George, Neil P. Blackledge, Graham Duddy, Neil L. Kelleher, Robert J. Klose, Martin Turner, Dinis P. Calado
Nat Commun. 2024; 15: 10516. Published online 2024 Dec 3. doi: 10.1038/s41467-024-54937-0
PMCID:
PMC11615350
AbstractArticlePDF–4.3M
2.
MicroRNA-721 regulates gluconeogenesis via KDM2A-mediated epigenetic modulation in diet-induced insulin resistance in C57BL/6J mice
Shaheen Wasil Kabeer, Shivam Sharma, Shalemraju Sriramdasu, Kulbhushan Tikoo
Biol Res. 2024; 57: 27. Published online 2024 May 14. doi: 10.1186/s40659-024-00495-0
PMCID:
PMC11092102
AbstractArticlePDF–15M
3.
KDM2A Deficiency in the Liver Promotes Abnormal Liver Function and Potential Liver Damage
Matthew Martin, Aishat Motolani, Hyeong-Geug Kim, Amy M. Collins, Faranak Alipourgivi, Jiamin Jin, Han Wei, Barry A. Wood, Yao-Ying Ma, X. Charlie Dong, Raghavendra G. Mirmira, Tao Lu
Biomolecules. 2023 Oct; 13(10): 1457. Published online 2023 Sep 27. doi: 10.3390/biom13101457
PMCID:
PMC10604476
AbstractArticlePDF–1.9M
4.
Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
Chen Chen, June Ho Shin, Zhuoqing Fang, Kevin Brennan, Nina B. Horowitz, Kathleen L. Pfaff, Emma L. Welsh, Scott J. Rodig, Olivier Gevaert, Or Gozani, Ravindra Uppaluri, John B. Sunwoo
Cancer Res. Author manuscript; available in PMC 2024 Feb 15.
Published in final edited form as: Cancer Res. 2023 Aug 15; 83(16): 2645–2655. doi: 10.1158/0008-5472.CAN-22-3114
PMCID:
PMC10526980
AbstractArticlePDF–1.6M
5.
Oocyte-Specific Knockout of Histone Lysine Demethylase KDM2a Compromises Fertility by Blocking the Development of Follicles and Oocytes
Xianrong Xiong, Xiaojian Zhang, Manzhen Yang, Yanjin Zhu, Hailing Yu, Xixi Fei, Fuko Mastuda, Daoliang Lan, Yan Xiong, Wei Fu, Shi Yin, Jian Li
Int J Mol Sci. 2022 Oct; 23(19): 12008. Published online 2022 Oct 9. doi: 10.3390/ijms231912008
PMCID:
PMC9570323
AbstractArticlePDF–4.6M
6.
Ablation of KDM2A Inhibits Preadipocyte Proliferation and Promotes Adipogenic Differentiation
Yonglin Hua, Yongqi Yue, Dan Zhao, Yan Ma, Yan Xiong, Xianrong Xiong, Jian Li
Int J Mol Sci. 2021 Sep; 22(18): 9759. Published online 2021 Sep 9. doi: 10.3390/ijms22189759
PMCID:
PMC8467897
AbstractArticlePDF–4.6M
7.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
TBX1 is required for normal stria vascularis and semicircular canal development
Cong Tian, Kenneth R. Johnson
Dev Biol. Author manuscript; available in PMC 2021 Feb 19.
Published in final edited form as: Dev Biol. 2020 Jan 1; 457(1): 91–103. Published online 2019 Sep 21. doi: 10.1016/j.ydbio.2019.09.013
PMCID:
PMC7893642
AbstractArticlePDF–3.5M
10.
SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair
Sarallah Rezazadeh, David Yang, Seyed Ali Biashad, Denis Firsanov, Masaki Takasugi, Michael Gilbert, Gregory Tombline, Natarajan V. Bhanu, Benjamin A. Garcia, Andrei Seluanov, Vera Gorbunova
Aging (Albany NY) 2020 Jun 30; 12(12): 11165–11184. Published online 2020 Jun 25. doi: 10.18632/aging.103567
PMCID:
PMC7343504
AbstractArticlePDF–2.1M
11.
KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity
Anne H Turberfield, Takashi Kondo, Manabu Nakayama, Yoko Koseki, Hamish W King, Haruhiko Koseki, Robert J Klose
Nucleic Acids Res. 2019 Sep 26; 47(17): 9005–9023. Published online 2019 Jul 31. doi: 10.1093/nar/gkz607
PMCID:
PMC6753492
AbstractArticlePDF–5.3M
12.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
The Histone Demethylase Jhdm1a Regulates Hepatic Gluconeogenesis
Dongning Pan, Chunxiao Mao, Tie Zou, Annie Y. Yao, Marcus P. Cooper, Victor Boyartchuk, Yong-Xu Wang
PLoS Genet. 2012 Jun; 8(6): e1002761. Published online 2012 Jun 14. doi: 10.1371/journal.pgen.1002761
PMCID:
PMC3375226
AbstractArticlePDF–835K
15.
Recognition of CpG Island Chromatin by KDM2A Requires Direct and Specific Interaction with Linker DNA
Jin C. Zhou, Neil P. Blackledge, Anca M. Farcas, Robert J. Klose
Mol Cell Biol. 2012 Jan; 32(2): 479–489. doi: 10.1128/MCB.06332-11
PMCID:
PMC3255781
AbstractArticlePDF–2.3M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
CpG Islands Recruit a Histone H3 Lysine 36 Demethylase
Neil P. Blackledge, Jin C. Zhou, Michael Y. Tolstorukov, Anca M. Farcas, Peter J. Park, Robert J. Klose
Mol Cell. 2010 Apr 23; 38(2-2): 179–190. doi: 10.1016/j.molcel.2010.04.009
PMCID:
PMC3098377
AbstractArticle
18.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
19.
Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65
Tao Lu, Mark W. Jackson, Benlian Wang, Maojing Yang, Mark R. Chance, Masaru Miyagi, Andrei V. Gudkov, George R. Stark
Proc Natl Acad Sci U S A. 2010 Jan 5; 107(1): 46–51. Published online 2009 Dec 29. doi: 10.1073/pnas.0912493107
PMCID:
PMC2806709
AbstractArticlePDF–777K
20.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K

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