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Items: 1 to 20 of 49

1.
Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function
Hannah Guak, Matthew Weiland, Alexandra Vander Ark, Lukai Zhai, Kin Lau, Mario Corrado, Paula Davidson, Ebenezer Asiedu, Batsirai Mabvakure, Shelby Compton, Lisa DeCamp, Catherine A. Scullion, Russell G. Jones, Sara M. Nowinski, Connie M. Krawczyk
Cell Rep. Author manuscript; available in PMC 2024 Sep 22.
Published in final edited form as: Cell Rep. 2024 Aug 27; 43(8): 114506. Published online 2024 Jul 24. doi: 10.1016/j.celrep.2024.114506
PMCID:
PMC11416765
AbstractArticlePDF–3.1M
2.
Histone demethylase JARID1C/KDM5C regulates Th17 cells by increasing IL-6 expression in diabetic plasmacytoid dendritic cells
Christopher O. Audu, Sonya J. Wolf, Amrita D. Joshi, Jadie Y. Moon, William J. Melvin, Sriganesh B. Sharma, Frank M. Davis, Andrea T. Obi, Rachel Wasikowski, Lam C. Tsoi, Emily C. Barrett, Kevin D. Mangum, Tyler M. Bauer, Steven L. Kunkel, Beth B. Moore, Katherine A. Gallagher
JCI Insight. 2024 Jun 24; 9(12): e172959. Published online 2024 Jun 24. doi: 10.1172/jci.insight.172959
PMCID:
PMC11383169
AbstractArticlePDF–1.3M
3.
WNT signalling control by KDM5C during development affects cognition
Violetta Karwacki-Neisius, Ahram Jang, Engin Cukuroglu, Albert Tai, Alan Jiao, Danilo Predes, Joon Yoon, Emily Brookes, Jiekai Chen, Aimee Iberg, Florian Halbritter, Katrin Õunap, Jozef Gecz, Thorsten M. Schlaeger, Shannan Ho Sui, Jonathan Göke, Xi He, Maria K. Lehtinen, Scott L. Pomeroy, Yang Shi
Nature. 2024; 627(8004): 594–603. Published online 2024 Feb 21. doi: 10.1038/s41586-024-07067-y
PMCID:
PMC10954547
AbstractArticlePDF–27M
4.
The histone demethylase KDM5C controls female bone mass by promoting energy metabolism in osteoclasts
Huadie Liu, Lukai Zhai, Ye Liu, Di Lu, Alexandra Vander Ark, Tao Yang, Connie M. Krawczyk
Sci Adv. 2023 Apr; 9(14): eadg0731. Published online 2023 Apr 5. doi: 10.1126/sciadv.adg0731
PMCID:
PMC10075994
AbstractArticlePDF–2.2M
5.
The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Mette Louise Trempenau, Mikkel Bruhn Schuster, Sachin Pundhir, Mafalda Araujo Pereira, Adrija Kalvisa, Marta Tapia, Jinyu Su, Ying Ge, Bauke de Boer, Alexander Balhuizen, Frederik Otzen Bagger, Pavel Shliaha, Patrycja Sroczynska, Julian Walfridsson, Kirsten Grønbæk, Kim Theilgaard-Mönch, Ole N. Jensen, Kristian Helin, Bo T. Porse
Leukemia. 2023; 37(3): 593–605. Published online 2023 Jan 12. doi: 10.1038/s41375-023-01810-6
PMCID:
PMC9991918
AbstractArticlePDF–2.4M
6.
Sexually Dimorphic Alterations in the Transcriptome and Behavior with Loss of Histone Demethylase KDM5C
Katherine M. Bonefas, Christina N. Vallianatos, Brynne Raines, Natalie C. Tronson, Shigeki Iwase
Cells. 2023 Feb; 12(4): 637. Published online 2023 Feb 16. doi: 10.3390/cells12040637
PMCID:
PMC9954040
AbstractArticlePDF–1.2M
7.
Alcohol‐associated fibrosis in females is mediated by female‐specific activation of lysine demethylases KDM5B and KDM5C
Michael Schonfeld, Janice Averilla, Sumedha Gunewardena, Steven A. Weinman, Irina Tikhanovich
Hepatol Commun. 2022 Aug; 6(8): 2042–2057. Published online 2022 Apr 25. doi: 10.1002/hep4.1967
PMCID:
PMC9315128
AbstractArticlePDF–6.5M
8.
Activation of Xist by an evolutionarily conserved function of KDM5C demethylase
Milan Kumar Samanta, Srimonta Gayen, Clair Harris, Emily Maclary, Yumie Murata-Nakamura, Rebecca M. Malcore, Robert S. Porter, Patricia M. Garay, Christina N. Vallianatos, Paul B. Samollow, Shigeki Iwase, Sundeep Kalantry
Nat Commun. 2022; 13: 2602. Published online 2022 May 11. doi: 10.1038/s41467-022-30352-1
PMCID:
PMC9095838
AbstractArticlePDF–3.6M
9.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
10.
The Second Oncogenic Hit Determines the Cell Fate of ETV6-RUNX1 Positive Leukemia
Guillermo Rodríguez-Hernández, Ana Casado-García, Marta Isidro-Hernández, Daniel Picard, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alberto Orfao, Oscar Blanco, Susana Riesco, Pablo Prieto-Matos, Francisco Javier García Criado, María Begoña García Cenador, Hanno Hock, Tariq Enver, Isidro Sanchez-Garcia, Carolina Vicente-Dueñas
Front Cell Dev Biol. 2021; 9: 704591. Published online 2021 Jul 15. doi: 10.3389/fcell.2021.704591
PMCID:
PMC8320889
AbstractArticlePDF–7.0M
11.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity
Jenny C. Link, Carrie B. Wiese, Xuqi Chen, Rozeta Avetisyan, Emilio Ronquillo, Feiyang Ma, Xiuqing Guo, Jie Yao, Matthew Allison, Yii-Der Ida Chen, Jerome I. Rotter, Julia S. El -Sayed Moustafa, Kerrin S. Small, Shigeki Iwase, Matteo Pellegrini, Laurent Vergnes, Arthur P. Arnold, Karen Reue
J Clin Invest. 2020 Nov 2; 130(11): 5688–5702. Published online 2020 Sep 28. doi: 10.1172/JCI140223
PMCID:
PMC7598065
AbstractArticlePDF–6.5M
14.
Mutually suppressive roles of KMT2A and KDM5C in behaviour, neuronal structure, and histone H3K4 methylation
Christina N. Vallianatos, Brynne Raines, Robert S. Porter, Katherine M. Bonefas, Michael C. Wu, Patricia M. Garay, Katie M. Collette, Young Ah Seo, Yali Dou, Catherine E. Keegan, Natalie C. Tronson, Shigeki Iwase
Commun Biol. 2020; 3: 278. Published online 2020 Jun 1. doi: 10.1038/s42003-020-1001-6
Correction in:
Commun Biol. 2020; 3: 331.
PMCID:
PMC7264178
AbstractArticlePDF–4.4M
15.
Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders
Loredana Poeta, Agnese Padula, Benedetta Attianese, Mariaelena Valentino, Lucia Verrillo, Stefania Filosa, Cheryl Shoubridge, Adriano Barra, Charles E Schwartz, Jesper Christensen, Hans van Bokhoven, Kristian Helin, Maria Brigida Lioi, Patrick Collombat, Jozef Gecz, Lucia Altucci, Elia Di Schiavi, Maria Giuseppina Miano
Hum Mol Genet. 2019 Dec 15; 28(24): 4089–4102. Published online 2019 Nov 6. doi: 10.1093/hmg/ddz254
PMCID:
PMC7002875
AbstractArticlePDF–1.4M
16.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
17.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
18.
Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons
Marilyn Scandaglia, Jose P. Lopez-Atalaya, Alejandro Medrano-Fernandez, Maria T. Lopez-Cascales, Beatriz del Blanco, Michal Lipinski, Eva Benito, Roman Olivares, Shigeki Iwase, Yang Shi, Angel Barco
Cell Rep. Author manuscript; available in PMC 2017 Nov 9.
Published in final edited form as: Cell Rep. 2017 Oct 3; 21(1): 47–59. doi: 10.1016/j.celrep.2017.09.014
PMCID:
PMC5679733
AbstractArticlePDF–2.4M
19.
Patient Mutations of the Intellectual Disability Gene KDM5C Down-Regulate Netrin G2 and Suppress Neurite Growth in Neuro2a Cells
Gengze Wei, Xinxian Deng, Saurabh Agarwal, Shigeki Iwase, Christine Disteche, Jun Xu
J Mol Neurosci. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: J Mol Neurosci. 2016 Sep; 60(1): 33–45. Published online 2016 Jul 16. doi: 10.1007/s12031-016-0770-3
PMCID:
PMC5412133
AbstractArticlePDF–681K
20.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M

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