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Select item 100701061.

Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice

Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson

JCI Insight. 2023 Mar 22; 8(6): e149360. Published online 2023 Mar 22. doi: 10.1172/jci.insight.149360

PMCID:: PMC10070106

Abstract Article PDF–3.1M

Select item 81770682.

Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions

Alex Zaufel, Sandra M.W. van de Wiel, Lu Yin, Günter Fauler, Daphne Chien, Xinzhong Dong, John F. Gilmer, Jennifer K. Truong, Paul A. Dawson, Stan F. J. van de Graaf, Peter Fickert, Tarek Moustafa

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Aug 1.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1; 1867(8): 166153. Published online 2021 Apr 22. doi: 10.1016/j.bbadis.2021.166153

PMCID:: PMC8177068

Abstract Article PDF–1.5M

Select item 45983563.

Maternal bile acid transporter deficiency promotes neonatal demise

Yuanyuan Zhang, Fei Li, Yao Wang, Aaron Pitre, Zhong-ze Fang, Matthew W. Frank, Christopher Calabrese, Kristopher W. Krausz, Geoffrey Neale, Sharon Frase, Peter Vogel, Charles O. Rock, Frank J. Gonzalez, John D. Schuetz

Nat Commun. 2015; 6: 8186. Published online 2015 Sep 29. doi: 10.1038/ncomms9186

PMCID:: PMC4598356

Abstract Article PDF–1.5M

Select item 43877664.

Ostα^−/− mice are not protected from western diet‐induced weight gain

Christine L. Hammond, Sadie G. Wheeler, Nazzareno Ballatori, Patricia M. Hinkle

Physiol Rep. 2015 Jan; 3(1): e12263. Published online 2015 Jan 27. doi: 10.14814/phy2.12263

PMCID:: PMC4387766

Abstract Article PDF–416K

Select item 39564435.

Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels

Laurent Vergnes, Jessica M. Lee, Robert G. Chin, Johan Auwerx, Karen Reue

Cell Metab. Author manuscript; available in PMC 2014 Jun 4.

Published in final edited form as: Cell Metab. 2013 Jun 4; 17(6): 916–928. doi: 10.1016/j.cmet.2013.04.007

PMCID:: PMC3956443

Abstract Article PDF–3.9M

Select item 39490216.

Ostα^−/− mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity

Sadie G. Wheeler, Christine L. Hammond, François R. Jornayvaz, Varman T. Samuel, Gerald I. Shulman, Carol J. Soroka, James L. Boyer, Patricia M. Hinkle, Nazzareno Ballatori

Am J Physiol Gastrointest Liver Physiol. 2014 Mar 1; 306(5): G425–G438. Published online 2013 Dec 31. doi: 10.1152/ajpgi.00368.2013

PMCID:: PMC3949021

Abstract Article

Select item 37242247.

Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE^−/− mice

Tian Lan, Jamie Haywood, Paul A. Dawson

Atherosclerosis. Author manuscript; available in PMC 2014 Aug 1.

Published in final edited form as: Atherosclerosis. 2013 Aug; 229(2): 374–380. Published online 2013 May 28. doi: 10.1016/j.atherosclerosis.2013.05.017

PMCID:: PMC3724224

Abstract Article PDF–1.4M

Select item 35755958.

Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism

Tian Lan, Anuradha Rao, Jamie Haywood, Nancy D. Kock, Paul A. Dawson

J Hepatol. Author manuscript; available in PMC 2013 Aug 1.

Published in final edited form as: J Hepatol. 2012 Aug; 57(2): 359–365. Published online 2012 Apr 25. doi: 10.1016/j.jhep.2012.03.025

PMCID:: PMC3575595

Abstract Article PDF–1.7M

Select item 33755459.

β-Subunit of the Ostα-Ostβ Organic Solute Transporter Is Required Not Only for Heterodimerization and Trafficking but Also for Function

Whitney V. Christian, Na Li, Patricia M. Hinkle, Nazzareno Ballatori

J Biol Chem. 2012 Jun 15; 287(25): 21233–21243. Published online 2012 Apr 25. doi: 10.1074/jbc.M112.352245

PMCID:: PMC3375545

Abstract Article PDF–2.9M

Select item 320292610.

Molecular Mechanisms of Altered Bile Acid Homeostasis in Organic Solute Transporter-Alpha Knockout Mice

Tian Lan, Jamie Haywood, Anuradha Rao, Paul A. Dawson

Dig Dis. 2011 Jun; 29(1): 18–22. doi: 10.1159/000324124

PMCID:: PMC3202926

Abstract Article PDF–155K

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317453912.

Ostα depletion protects liver from oral bile acid load

Carol J. Soroka, Heino Velazquez, Albert Mennone, Nazzareno Ballatori, James L. Boyer

Am J Physiol Gastrointest Liver Physiol. 2011 Sep; 301(3): G574–G579. Published online 2011 Jun 30. doi: 10.1152/ajpgi.00141.2011

PMCID:: PMC3174539

Abstract Article

Select item 302253413.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 293996114.

Neurosteroid transport by the organic solute transporter OSTα-OSTβ

Fang Fang, Whitney V. Christian, Sadie G. Gorman, Mei Cui, Jiaoti Huang, Kim Tieu, Nazzareno Ballatori

J Neurochem. Author manuscript; available in PMC 2011 Oct 1.

Published in final edited form as: J Neurochem. 2010 Oct; 115(1): 220–233. Published online 2010 Aug 12. doi: 10.1111/j.1471-4159.2010.06920.x

PMCID:: PMC2939961

Abstract Article PDF–2.3M

Select item 281982015.

Mouse organic solute transporter α deficiency enhances renal excretion of bile acids and attenuates cholestasis

Carol J. Soroka, Albert Mennone, Lee R. Hagey, Nazzareno Ballatori, James L. Boyer

Hepatology. Author manuscript; available in PMC 2011 Jan 1.

Published in final edited form as: Hepatology. 2010 Jan; 51(1): 181–190. doi: 10.1002/hep.23265

PMCID:: PMC2819820

Abstract Article PDF–642K

Select item 255627016.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108