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Select item 111663711.

Enhanced TRPC3 transcription through AT1R/PKA/CREB signaling contributes to mitochondrial dysfunction in renal tubular epithelial cells in D‐galactose‐induced accelerated aging mice

Bin Wang, Wenpei Yu, Weiguang Zhang, Min Zhang, Yue Niu, Xinye Jin, Jie Zhang, Ding Sun, Hao Li, Zehao Zhang, Qing Luo, Xiaowei Cheng, Jingxue Niu, Guangyan Cai, Xiangmei Chen, Yizhi Chen

Aging Cell. 2024 Jun; 23(6): e14130. Published online 2024 Feb 28. doi: 10.1111/acel.14130

PMCID:: PMC11166371

Abstract Article PDF–31M

Select item 111482822.

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao

Front Pharmacol. 2024; 15: 1392328. Published online 2024 May 21. doi: 10.3389/fphar.2024.1392328

PMCID:: PMC11148282

Abstract Article PDF–5.1M

Select item 110844763.

The Rise in Tubular pH during Hypercalciuria Exacerbates Calcium Stone Formation

Farai C. Gombedza, Samuel Shin, Jaclyn Sadiua, George B. Stackhouse, Bidhan C. Bandyopadhyay

Int J Mol Sci. 2024 May; 25(9): 4787. Published online 2024 Apr 27. doi: 10.3390/ijms25094787

PMCID:: PMC11084476

Abstract Article PDF–3.8M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109021305.

A role for TRPC3 in mammalian testis development

Zhenhua Ming, Stefan Bagheri-Fam, Emily R. Frost, Janelle M. Ryan, Brittany Vining, Vincent R. Harley

Front Cell Dev Biol. 2024; 12: 1337714. Published online 2024 Feb 15. doi: 10.3389/fcell.2024.1337714

Correction in:: Front Cell Dev Biol. 2024; 12: 1484634.

PMCID:: PMC10902130

Abstract Article PDF–5.5M

Select item 107180176.

TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca²⁺ concentration in mouse cardiomyocytes

Yohei Yamaguchi, Gentaro Iribe, Toshiyuki Kaneko, Ken Takahashi, Takuro Numaga-Tomita, Motohiro Nishida, Lutz Birnbaumer, Keiji Naruse

J Physiol Sci. 2018 Mar; 68(2): 153–164. Published online 2017 Jan 19. doi: 10.1007/s12576-016-0519-3

PMCID:: PMC10718017

Abstract Article PDF–1.2M

Select item 104547667.

Canonical Transient Receptor Potential Channel 3 Contributes to Cerebral Blood Flow Changes Associated with Cortical Spreading Depression in Mice

Fang Zheng

Int J Mol Sci. 2023 Aug; 24(16): 12611. Published online 2023 Aug 9. doi: 10.3390/ijms241612611

PMCID:: PMC10454766

Abstract Article PDF–1.9M

Select item 103790218.

Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice

Do-Yang Park, Woon Heo, Miran Kang, Taeyoung Ahn, DoHyeon Kim, Ayeon Choi, Lutz Birnbaumer, Hyung-Ju Cho, Joo Young Kim

Int J Mol Sci. 2023 Jul; 24(14): 11284. Published online 2023 Jul 10. doi: 10.3390/ijms241411284

PMCID:: PMC10379021

Abstract Article PDF–2.0M

Select item 102588339.

Ablation of TRPC3 compromises bicarbonate and phosphate transporter activity in mice proximal tubular cells

Samuel Shin, Eugenia Awuah Boadi, Bidhan C. Bandyopadhyay

Clin Exp Pharmacol Physiol. Author manuscript; available in PMC 2024 Jan 1.

Published in final edited form as: Clin Exp Pharmacol Physiol. 2023 Mar; 50(3): 247–255. Published online 2022 Dec 18. doi: 10.1111/1440-1681.13741

PMCID:: PMC10258833

Abstract Article PDF–1.2M

Select item 1008276910.

Ablation of TRPC3 disrupts Ca²⁺ signaling in salivary ductal cells and promotes sialolithiasis

Bok-Eum Choi, Samuel Shin, Sade Evans, Brij B. Singh, Bidhan C. Bandyopadhyay

Sci Rep. 2023; 13: 5772. Published online 2023 Apr 8. doi: 10.1038/s41598-023-32602-8

PMCID:: PMC10082769

Abstract Article PDF–2.7M

Select item 995131411.

TRPC3 Regulates Islet Beta‐Cell Insulin Secretion

Gaëlle Rached, Youakim Saliba, Dina Maddah, Joelle Hajal, Viviane Smayra, Jules‐Joel Bakhos, Klaus Groschner, Lutz Birnbaumer, Nassim Fares

Adv Sci (Weinh) 2023 Feb; 10(6): 2204846. Published online 2023 Jan 15. doi: 10.1002/advs.202204846

PMCID:: PMC9951314

Abstract Article PDF–4.2M

Select item 976832812.

Deletion of classical transient receptor potential 1, 3 and 6 alters pulmonary vasoconstriction in chronic hypoxia-induced pulmonary hypertension in mice

Kathrin Malkmus, Monika Brosien, Fenja Knoepp, Lisa Schaffelhofer, Friedrich Grimminger, Christoph Rummel, Thomas Gudermann, Alexander Dietrich, Lutz Birnbaumer, Norbert Weissmann, Simone Kraut

Front Physiol. 2022; 13: 1080875. Published online 2022 Dec 7. doi: 10.3389/fphys.2022.1080875

PMCID:: PMC9768328

Abstract Article PDF–2.4M

Select item 957477713.

Store-operated Ca²⁺ entry and Ca²⁺ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1−/− and heptaTRPC knockout mice

Lucía Núñez, Gary S. Bird, Elena Hernando-Pérez, Enrique Pérez-Riesgo, James W. Putney, Jr, Carlos Villalobos

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2022 Oct 17.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2019 Jul; 1866(7): 1124–1136. Published online 2018 Nov 17. doi: 10.1016/j.bbamcr.2018.11.006

PMCID:: PMC9574777

Abstract Article PDF–1.8M

Select item 954950714.

Increase in membrane surface expression and phosphorylation of TRPC3 related to olfactory dysfunction in α‐synuclein transgenic mice

Min Chen, Jia Liu, Hanjiang Luo, Chunli Duan, Ge Gao, Hui Yang

J Cell Mol Med. 2022 Oct; 26(19): 5008–5020. Published online 2022 Aug 27. doi: 10.1111/jcmm.17524

PMCID:: PMC9549507

Abstract Article PDF–11M

Select item 937551015.

Sodium‐Glucose Cotransporter 2 Inhibitor Canagliflozin Antagonizes Salt‐Sensitive Hypertension Through Modifying Transient Receptor Potential Channels 3 Mediated Vascular Calcium Handling

Yu Zhao, Li Li, Zongshi Lu, Yingru Hu, Hexuan Zhang, Fang Sun, Qiang Li, Chengkang He, Wentao Shu, Lijuan Wang, Tingbing Cao, Zhidan Luo, Zhencheng Yan, Daoyan Liu, Peng Gao, Zhiming Zhu

J Am Heart Assoc. 2022 Aug 2; 11(15): e025328. Published online 2022 Jul 29. doi: 10.1161/JAHA.121.025328

Correction in:: J Am Heart Assoc. 2023 Apr 4; 12(7): e027656.

PMCID:: PMC9375510

Abstract Article PDF–17M

Select item 926611116.

A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia

Tsukasa Shimauchi, Takuro Numaga-Tomita, Yuri Kato, Hiroyuki Morimoto, Kosuke Sakata, Ryosuke Matsukane, Akiyuki Nishimura, Kazuhiro Nishiyama, Atsushi Shibuta, Yutoku Horiuchi, Hitoshi Kurose, Sang Geon Kim, Yasuteru Urano, Takashi Ohshima, Motohiro Nishida

Cells. 2022 Jul; 11(13): 2041. Published online 2022 Jun 27. doi: 10.3390/cells11132041

PMCID:: PMC9266111

Abstract Article PDF–3.1M

Select item 861097417.

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation

Rin Khang, Areum Jo, Hojin Kang, Hanna Kim, Eunsang Kwag, Ji-Yeong Lee, Okjae Koo, Jinsu Park, Hark Kyun Kim, Dong-Gyu Jo, Inwoo Hwang, Jee-Yin Ahn, Yunjong Lee, Jeong-Yun Choi, Yun-Song Lee, Joo-Ho Shin

Sci Rep. 2021; 11: 22745. Published online 2021 Nov 23. doi: 10.1038/s41598-021-02218-x

PMCID:: PMC8610974

Abstract Article PDF–2.5M

Select item 845657218.

TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons

Ki Bum Um, Suyun Hahn, So Woon Kim, Yoon Je Lee, Lutz Birnbaumer, Hyun Jin Kim, Myoung Kyu Park

eLife. 2021; 10: e70920. Published online 2021 Aug 19. doi: 10.7554/eLife.70920

PMCID:: PMC8456572

Abstract Article PDF–6.2M

Select item 823328319.

Mapping the expression of transient receptor potential channels across murine placental development

Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens

Cell Mol Life Sci. 2021 Jun; 78(11): 4993–5014. Published online 2021 Apr 21. doi: 10.1007/s00018-021-03837-3

PMCID:: PMC8233283

Abstract Article PDF–4.1M

Select item 732635320.

TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations

John J. O'Malley, Frederik Seibt, Jeannie Chin, Michael Beierlein

J Neurosci. 2020 Jun 17; 40(25): 4813–4823. doi: 10.1523/JNEUROSCI.0324-20.2020

PMCID:: PMC7326353

Abstract Article PDF–2.0M

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