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Select item 114236781.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 113201222.

Endoplasmic reticulum and inner nuclear membrane ubiquitin-conjugating enzymes Ubc6 and Ubc7 confer resistance to hygromycin B in Saccharomyces cerevisiae

Sophia L Owutey, Katrina A Procuniar, Emmanuel Akoto, Jacob C Davis, Rachel M Vachon, LiLi F O'Malley, Hayden O Schneider, Philip J Smaldino, Jason D True, Ashley L Kalinski, Eric M Rubenstein

MicroPubl Biol. 2024; 2024: 10.17912/micropub.biology.001276. Published online 2024 Jul 29. doi: 10.17912/micropub.biology.001276

PMCID:: PMC11320122

Abstract Article PDF–1021K

Select item 109281203.

Substrate recognition mechanism of the endoplasmic reticulum-associated ubiquitin ligase Doa10

Kevin Wu, Samuel Itskanov, Diane L. Lynch, Yuanyuan Chen, Aasha Turner, James C. Gumbart, Eunyong Park

Nat Commun. 2024; 15: 2182. Published online 2024 Mar 11. doi: 10.1038/s41467-024-46409-2

PMCID:: PMC10928120

Abstract Article PDF–5.2M

Select item 107001384.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 105517005.

Misregulation of cell cycle-dependent methylation of budding yeast CENP-A contributes to chromosomal instability

Prashant K. Mishra, Wei-Chun Au, Pedro G. Castineira, Nazrin Ali, John Stanton, Lars Boeckmann, Yoshimitsu Takahashi, Michael Costanzo, Charles Boone, Kerry S. Bloom, Peter H. Thorpe, Munira A. Basrai

Mol Biol Cell. 2023 Sep 1; 34(10): ar99. Published online 2023 Aug 17. doi: 10.1091/mbc.E23-03-0108

PMCID:: PMC10551700

Abstract Article PDF–3.7M

Select item 102977006.

The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

Janhavi A. Kolhe, Neethu L. Babu, Brian C. Freeman

Mol Cell. Author manuscript; available in PMC 2024 Jun 15.

Published in final edited form as: Mol Cell. 2023 Jun 15; 83(12): 2035–2044.e7. Published online 2023 Jun 8. doi: 10.1016/j.molcel.2023.05.021

PMCID:: PMC10297700

Abstract Article PDF–2.0M

Select item 101039817.

Deep mutational scanning highlights a new role for cytosolic regions in Hrd1 function

Brian G. Peterson, Jiwon Hwang, Jennifer E. Russ, Jeremy Schroeder, Peter L. Freddolino, Ryan D. Baldridge

Version 1. bioRxiv. Preprint. 2023 Apr 3. doi: 10.1101/2023.04.03.535444

Published in:: Cell Rep. 2023 Nov 28; 42(11): 113451.

PMCID:: PMC10103981

Abstract Article PDF–5.6M

Select item 96527728.

Lipid saturation induces degradation of squalene epoxidase for sterol homeostasis and cell survival

Leng-Jie Huang, Rey-Huei Chen

Life Sci Alliance. 2023 Jan; 6(1): e202201612. Published online 2022 Nov 11. doi: 10.26508/lsa.202201612

PMCID:: PMC9652772

Abstract Article PDF–3.9M

Select item 96309869.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 961935010.

Elements of the ERAD ubiquitin ligase Doa10 regulating sequential poly-ubiquitylation of its targets

Adrian B. Mehrtash, Mark Hochstrasser

iScience. 2022 Nov 18; 25(11): 105351. Published online 2022 Oct 13. doi: 10.1016/j.isci.2022.105351

PMCID:: PMC9619350

Abstract Article PDF–4.1M

Select item 920981111.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916991312.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 857691713.

Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis

Emmanuel T. Nsamba, Abesh Bera, Michael Costanzo, Charles Boone, Mohan L. Gupta, Jr.

J Cell Biol. 2021 Dec 6; 220(12): e202010155. Published online 2021 Nov 5. doi: 10.1083/jcb.202010155

PMCID:: PMC8576917

Abstract Article PDF–7.4M

Select item 842120414.

Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast

Laurence Decourty, Christophe Malabat, Emmanuel Frachon, Alain Jacquier, Cosmin Saveanu

Nucleic Acids Res. 2021 Sep 7; 49(15): 8535–8555. Published online 2021 Aug 6. doi: 10.1093/nar/gkab680

PMCID:: PMC8421204

Abstract Article PDF–2.9M

Select item 795739815.

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains

Lukas Pluska, Ernst Jarosch, Henrik Zauber, Andreas Kniss, Anita Waltho, Katrin Bagola, Maximilian von Delbrück, Frank Löhr, Brenda A Schulman, Matthias Selbach, Volker Dötsch, Thomas Sommer

EMBO J. 2021 Mar 15; 40(6): e106094. Published online 2021 Feb 12. doi: 10.15252/embj.2020106094