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Items: 1 to 20 of 882

1.
SHC-3: a previously unidentified C. elegans Shc family member functions in the insulin-like signaling pathway to enhance survival during L1 arrest
Mercedes Di Bernardo, Victoria L León Guerrero, Jacob C Sutoski, William Rod Hardy, Lesley T MacNeil
Genetics. 2024 Oct; 228(2): iyae093. Published online 2024 Jun 11. doi: 10.1093/genetics/iyae093
PMCID:
PMC11630764
ArticlePDF–1.5M
2.
Non-cell-autonomous regulation of germline proteostasis by insulin/IGF-1 signaling-induced dietary peptide uptake via PEPT-1
Tahir Muhammad, Stacey L Edwards, Allison C Morphis, Mary V Johnson, Vitor De Oliveira, Tomasz Chamera, Siyan Liu, Ngoc Gia Tuong Nguyen, Jian Li
EMBO J. 2024 Nov; 43(21): 4892–4921. Published online 2024 Sep 16. doi: 10.1038/s44318-024-00234-x
PMCID:
PMC11535032
ArticlePDF–8.9M
3.
Clerodendranthus spicatus (Thunb.) Water Extracts Reduce Lipid Accumulation and Oxidative Stress in the Caenorhabditis elegans
Xian Xiao, Fanhua Wu, Bing Wang, Zeping Cai, Lanying Wang, Yunfei Zhang, Xudong Yu, Yanping Luo
Int J Mol Sci. 2024 Sep; 25(17): 9655. Published online 2024 Sep 6. doi: 10.3390/ijms25179655
PMCID:
PMC11394974
ArticlePDF–4.6M
4.
Peroxiredoxin 2 regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing
Qin Xia, Penglin Li, José C. Casas-Martinez, Antonio Miranda-Vizuete, Emma McDermott, Peter Dockery, Katarzyna Goljanek-Whysall, Brian McDonagh
Mol Metab. 2024 Oct; 88: 102003. Published online 2024 Aug 6. doi: 10.1016/j.molmet.2024.102003
PMCID:
PMC11388264
ArticlePDF–4.0M
5.
Anoectochilus roxburghii Extract Extends the Lifespan of Caenorhabditis elegans through Activating the daf-16/FoxO Pathway
Peng Xu, Jianfeng Wang, Junyi Wang, Xiaoxiao Hu, Wei Wang, Shengmin Lu, Yingkun Sheng
Antioxidants (Basel) 2024 Aug; 13(8): 945. Published online 2024 Aug 2. doi: 10.3390/antiox13080945
PMCID:
PMC11351832
ArticlePDF–11M
6.
Uncovering the Molecular Pathways Implicated in the Anti-Cancer Activity of the Imidazoquinoxaline Derivative EAPB02303 Using a Caenorhabditis elegans Model
Perla Makhoul, Simon Galas, Stéphanie Paniagua-Gayraud, Carine Deleuze-Masquefa, Hiba El Hajj, Pierre-Antoine Bonnet, Myriam Richaud
Int J Mol Sci. 2024 Jul; 25(14): 7785. Published online 2024 Jul 16. doi: 10.3390/ijms25147785
PMCID:
PMC11277376
ArticlePDF–2.3M
7.
Combinatorial transcriptomic and genetic dissection of insulin/IGF‐1 signaling‐regulated longevity in Caenorhabditis elegans
Seokjin Ham, Sieun S. Kim, Sangsoon Park, Hyunwoo C. Kwon, Seokjun G. Ha, Yunkyu Bae, Gee‐Yoon Lee, Seung‐Jae V. Lee
Aging Cell. 2024 Jul; 23(7): e14151. Published online 2024 Mar 26. doi: 10.1111/acel.14151
PMCID:
PMC11258480
ArticlePDF–1.4M
8.
The clinical antiprotozoal drug nitazoxanide and its metabolite tizoxanide extend Caenorhabditis elegans lifespan and healthspan
Wenfeng Li, Shuming Chen, Jing Lang, Jing Luo, Jiahui Chen, Liping Zhang, Zhijie Sun, Deli Dong
Acta Pharm Sin B. 2024 Jul; 14(7): 3266–3280. Published online 2024 Mar 28. doi: 10.1016/j.apsb.2024.03.031
PMCID:
PMC11252460
ArticlePDF–4.0M
9.
Influence of Oleacein, an Olive Oil and Olive Mill Wastewater Phenolic Compound, on Caenorhabditis elegans Longevity and Stress Resistance
Morgane Carrara, Myriam Richaud, Pierre Cuq, Simon Galas, Delphine Margout-Jantac
Foods. 2024 Jul; 13(13): 2146. Published online 2024 Jul 5. doi: 10.3390/foods13132146
PMCID:
PMC11241402
ArticlePDF–2.4M
10.
Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans
Makoto Horikawa, Masamitsu Fukuyama, Adam Antebi, Masaki Mizunuma
Nat Commun. 2024; 15: 5793. Published online 2024 Jul 10. doi: 10.1038/s41467-024-50111-8
PMCID:
PMC11237089
ArticlePDF–11M
11.
The neuron-specific IIS/FOXO transcriptome in aged animals reveals regulatory mechanisms of cognitive aging
Yifei Weng, Shiyi Zhou, Katherine Morillo, Rachel Kaletsky, Sarah Lin, Coleen T Murphy
eLife. 2024; 13: RP95621. Published online 2024 Jun 26. doi: 10.7554/eLife.95621
PMCID:
PMC11208049
ArticlePDF–4.7M
12.
Exploring the Impact of French Raw-Milk Cheeses on Oxidative Process Using Caenorhabditis elegans and Human Leukocyte Models
Anna Diet, Christophe Poix, Muriel Bonnet, Christian Coelho, Isabelle Ripoche, Caroline Decombat, Julien Priam, Etienne Saunier, Pierre Chalard, Stéphanie Bornes, Florence Caldefie-Chezet, Laurent Rios
Nutrients. 2024 Jun; 16(12): 1862. Published online 2024 Jun 13. doi: 10.3390/nu16121862
PMCID:
PMC11206881
ArticlePDF–3.1M
13.
The Probiotic Strain Lactobacillus acidophilus CL1285 Reduces Fat Deposition and Oxidative Stress and Increases Lifespan in Caenorhabditis elegans
Samir Bouasker, Sonja Nodland, Mathieu Millette
Microorganisms. 2024 Jun; 12(6): 1036. Published online 2024 May 21. doi: 10.3390/microorganisms12061036
PMCID:
PMC11205358
ArticlePDF–2.8M
14.
Jujubae Fructus extract prolongs lifespan and improves stress tolerance in Caenorhabditis elegans dependent on DAF-16/SOD-3
Zhi Zhang, Jiajia Li, Feng Li, Tao Wang, Xiaoyan Luo, Bing Li, Yilin You, Changjing Wu, Xiaomeng Liu
Sci Rep. 2024; 14: 13713. Published online 2024 Jun 14. doi: 10.1038/s41598-024-64045-0
PMCID:
PMC11178930
ArticlePDF–2.1M
15.
4,4′-methylenediphenol reduces Aβ-induced toxicity in a Caenorhabditis elegans model of Alzheimer’s disease
Xingzhi Yu, Jie Tao, Tian Xiao, Xiaohua Duan
Front Aging Neurosci. 2024; 16: 1393721. Published online 2024 May 30. doi: 10.3389/fnagi.2024.1393721
PMCID:
PMC11171718
ArticlePDF–9.4M
16.
DOS-3 mediates cell-non-autonomous DAF-16/FOXO activity in antagonizing age-related loss of C. elegans germline stem/progenitor cells
Zhifei Zhang, Haiyan Yang, Lei Fang, Guangrong Zhao, Jun Xiang, Jialin C. Zheng, Zhao Qin
Nat Commun. 2024; 15: 4904. Published online 2024 Jun 8. doi: 10.1038/s41467-024-49318-6
PMCID:
PMC11162419
ArticlePDF–4.2M
17.
2-Butoxytetrahydrofuran, Isolated from Holothuria scabra, Attenuates Aggregative and Oxidative Properties of α-Synuclein and Alleviates Its Toxicity in a Transgenic Caenorhabditis elegans Model of Parkinson’s Disease
Sukrit Promtang, Tanatcha Sanguanphun, Pawanrat Chalorak, Laurence S. Pe, Nakorn Niamnont, Prasert Sobhon, Krai Meemon
ACS Chem Neurosci. 2024 Jun 5; 15(11): 2182–2197. Published online 2024 May 10. doi: 10.1021/acschemneuro.4c00008
PMCID:
PMC11157484
ArticlePDF–8.0M
18.
Time-course swRNA-seq uncovers a hierarchical gene regulatory network in controlling the response-repair-remodeling after wounding
Xinghai Yu, Jinghua Zhou, Wenkai Ye, Jingxiu Xu, Rui Li, Li Huang, Yi Chai, Miaomiao Wen, Suhong Xu, Yu Zhou
Commun Biol. 2024; 7: 694. Published online 2024 Jun 6. doi: 10.1038/s42003-024-06352-w
PMCID:
PMC11156874
ArticlePDF–10M
19.
P-hydroxybenzaldehyde protects Caenorhabditis elegans from oxidative stress and β-amyloid toxicity
Xingzhi Yu, Jie Tao, Tian Xiao, Xiaohua Duan
Front Aging Neurosci. 2024; 16: 1414956. Published online 2024 May 22. doi: 10.3389/fnagi.2024.1414956
PMCID:
PMC11150654
ArticlePDF–6.1M
20.
Loss of the ceramide synthase HYL-2 from Caenorhabditis elegans impairs stress responses and alters sphingolipid composition
Huaiyi Zhu, Yunfei You, Boming Yu, Zhitao Deng, Min Liu, Zhenying Hu, Jingjing Duan
J Biol Chem. 2024 Jun; 300(6): 107320. Published online 2024 Apr 25. doi: 10.1016/j.jbc.2024.107320
PMCID:
PMC11145541
ArticlePDF–1.6M

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