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Select item 113361361.

The C. elegans Myc-family of transcription factors coordinate a dynamic adaptive response to dietary restriction

Adam B. Cornwell, Yun Zhang, Manjunatha Thondamal, David W. Johnson, Juilee Thakar, Andrew V. Samuelson

GeroScience. 2024 Oct; 46(5): 4827–4854. Published online 2024 Jun 15. doi: 10.1007/s11357-024-01197-x

PMCID:: PMC11336136

Abstract Article PDF–4.0M

Select item 110722722.

EAT-2 attenuates C. elegans development via metabolic remodeling in a chemically defined food environment

Xuwen Cao, Yusu Xie, Hanwen Yang, Peiqi Sun, Beining Xue, L. Rene Garcia, Liusuo Zhang

Cell Mol Life Sci. 2023 Aug; 80(8): 205. Published online 2023 Jul 14. doi: 10.1007/s00018-023-04849-x

PMCID:: PMC11072272

Abstract Article PDF–4.4M

Select item 110039583.

An Intricate Network Involving the Argonaute ALG-1 Modulates Organismal Resistance to Oxidative Stress

Carlos A. Vergani-Junior, Raíssa De P. Moro, Silas Pinto, Evandro A. De-Souza, Henrique Camara, Deisi L. Braga, Guilherme Tonon-da-Silva, Thiago L. Knittel, Gabriel P. Ruiz, Raissa G. Ludwig, Katlin B. Massirer, William B. Mair, Marcelo A. Mori

Nat Commun. 2024; 15: 3070. Published online 2024 Apr 9. doi: 10.1038/s41467-024-47306-4

PMCID:: PMC11003958

Abstract Article PDF–1.9M

Select item 109180634.

Dietary E. coli promotes age-dependent chemotaxis decline in C. elegans

Nadia Suryawinata, Rikuou Yokosawa, Ke Hui Cassandra Tan, Alison Lok Lai, Ryusei Sone, Ikue Mori, Kentaro Noma

Sci Rep. 2024; 14: 5529. Published online 2024 Mar 6. doi: 10.1038/s41598-024-52272-4

PMCID:: PMC10918063

Abstract Article PDF–2.3M

Select item 108282695.

In-vivo screening implicates endoribonuclease Regnase-1 in modulating senescence-associated lysosomal changes

Richard Venz, Anita Goyala, Abel Soto-Gamez, Tugce Yenice, Marco Demaria, Collin Y. Ewald

GeroScience. 2024 Apr; 46(2): 1499–1514. Published online 2023 Aug 29. doi: 10.1007/s11357-023-00909-z

PMCID:: PMC10828269

Abstract Article PDF–3.0M

Select item 103538276.

Multiple pals gene modules control a balance between immunity and development in Caenorhabditis elegans

Vladimir Lažetić, Michael J. Blanchard, Theresa Bui, Emily R. Troemel

PLoS Pathog. 2023 Jul; 19(7): e1011120. Published online 2023 Jul 18. doi: 10.1371/journal.ppat.1011120

PMCID:: PMC10353827

Abstract Article PDF–4.6M

Select item 102562357.

A worm’s life: AMPK links muscle mitochondrial dynamics to physical fitness and healthy aging in Caenorhabditis elegans

Vihang A. Narkar

J Cardiovasc Aging. Author manuscript; available in PMC 2023 Jun 9.

Published in final edited form as: J Cardiovasc Aging. 2023; 3(3): 25. Published online 2023 May 4. doi: 10.20517/jca.2023.14

PMCID:: PMC10256235

Article PDF–237K

Select item 102364458.

Increased Alcohol Dehydrogenase 1 activity promotes longevity

Abbas Ghaddar, Vinod K. Mony, Swarup Mishra, Samuel Berhanu, James C. Johnson, Elisa Enriquez-Hesles, Emma Harrison, Aaroh Patel, Mary Kate Horak, Jeffrey S. Smith, Eyleen J. O’Rourke

Curr Biol. Author manuscript; available in PMC 2024 Mar 27.

Published in final edited form as: Curr Biol. 2023 Mar 27; 33(6): 1036–1046.e6. Published online 2023 Feb 17. doi: 10.1016/j.cub.2023.01.059

PMCID:: PMC10236445

Abstract Article PDF–1.3M

Select item 102291329.

Bacterial diet affects the age-dependent decline of associative learning in Caenorhabditis elegans

Satoshi Higurashi, Sachio Tsukada, Binta Maria Aleogho, Joo Hyun Park, Yana Al-Hebri, Masaru Tanaka, Shunji Nakano, Ikue Mori, Kentaro Noma

eLife. 2023; 12: e81418. Published online 2023 May 30. doi: 10.7554/eLife.81418

PMCID:: PMC10229132

Abstract Article PDF–1.0M

Select item 1015423610.

Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity

Wenming Huang, Chun Kew, Stephanie de Alcantara Fernandes, Anna Löhrke, Lynn Han, Constantinos Demetriades, Adam Antebi

Nat Aging. 2022; 2(9): 796–808. Published online 2022 Sep 19. doi: 10.1038/s43587-022-00275-z

PMCID:: PMC10154236

Abstract Article PDF–17M

Select item 1008652111.

The conserved microRNA‐229 family controls low‐insulin signaling and dietary restriction induced longevity through interactions with SKN‐1/NRF2

Latika Matai, Thalyana Stathis, Jonathan D. Lee, Christine Parsons, Tanvi Saxena, Kovi Shlomchik, Frank J. Slack

Aging Cell. 2023 Apr; 22(4): e13785. Published online 2023 Feb 7. doi: 10.1111/acel.13785

PMCID:: PMC10086521

Abstract Article PDF–5.0M

Select item 1006952312.

Gold Nanoparticles Reduce Food Sensation in Caenorhabditis elegans via the Voltage-Gated Channel EGL-19

Meimei Wang, Zhenzhen Zhang, Ning Sun, Baolin Yang, Jihao Mo, Daping Wang, Mingqin Su, Jian Hu, Miaomiao Wang, Lei Wang

Int J Nanomedicine. 2023; 18: 1659–1676. Published online 2023 Mar 30. doi: 10.2147/IJN.S394666

Correction in:: Int J Nanomedicine. 2023; 18: 2797–2798.

PMCID:: PMC10069523

Abstract Article PDF–11M

Select item 997031213.

The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Trisha A. Staab, Grace McIntyre, Lu Wang, Joycelyn Radeny, Lisa Bettcher, Melissa Guillen, Margaret P. Peck, Azia P. Kalil, Samantha P. Bromley, Daniel Raftery, Jason P. Chan

Aging (Albany NY) 2023 Feb 14; 15(3): 650–674. Published online 2023 Feb 13. doi: 10.18632/aging.204515

PMCID:: PMC9970312

Abstract Article PDF–2.0M

Select item 992627814.

Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics

Juliane Cruz Campos, Luiz Henrique Marchesi Bozi, Barbara Krum, Luiz Roberto Grassmann Bechara, Nikolas Dresch Ferreira, Gabriel Santos Arini, Rudá Prestes Albuquerque, Annika Traa, Takafumi Ogawa, Alexander M. van der Bliek, Afshin Beheshti, Edward T. Chouchani, Jeremy M. Van Raamsdonk, T. Keith Blackwell, Julio Cesar Batista Ferreira

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2204750120. Published online 2023 Jan 3. doi: 10.1073/pnas.2204750120