PMC Links for GEO Profiles (Select 52737068) - PMC

Select item 110227501.

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons

Yongzhi Yang, Meghan Lee Arnold, Caitlin M. Lange, Ling-Hsuan Sun, Michael Broussalian, Saam Doroodian, Hiroshi Ebata, Elizabeth H. Choy, Karie Poon, Tatiana M. Moreno, Anupama Singh, Monica Driscoll, Caroline Kumsta, Malene Hansen

Nat Aging. Author manuscript; available in PMC 2024 Apr 17.

Published in final edited form as: Nat Aging. 2024 Feb; 4(2): 198–212. Published online 2024 Jan 4. doi: 10.1038/s43587-023-00548-1

PMCID:: PMC11022750

Abstract Article PDF–4.4M

Select item 108762122.

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

Yong Yu, Shihong M Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu, Bentian Jing, Qian Zhao, David M Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C Wang

eLife. 2024; 13: e85214. Published online 2024 Jan 19. doi: 10.7554/eLife.85214

PMCID:: PMC10876212

Abstract Article PDF–5.9M

Select item 106122393.

Liensinine and neferine exert neuroprotective effects via the autophagy pathway in transgenic Caenorhabditis elegans

Meng-chen Wu, Ye-hui Gao, Chen Zhang, Bo-tian Ma, Hong-ru Lin, Jin-yun Jiang, Meng-fan Xue, Shan Li, Hong-bing Wang

BMC Complement Med Ther. 2023; 23: 386. Published online 2023 Oct 27. doi: 10.1186/s12906-023-04183-6

PMCID:: PMC10612239

Abstract Article PDF–2.2M

Select item 104728634.

The active zone protein CLA-1 (Clarinet) bridges two subsynaptic domains to regulate presynaptic sorting of ATG-9

Zhao Xuan, Daniel A. Colón-Ramos

Autophagy. 2023; 19(10): 2807–2808. Published online 2023 Jun 30. doi: 10.1080/15548627.2023.2229227

PMCID:: PMC10472863

Abstract Article PDF–417K

Select item 103356765.

Partial inhibition of class III PI3K VPS-34 ameliorates motor aging and prolongs health span

Zhongliang Hu, Yamei Luo, Yuting Liu, Yaru Luo, Liangce Wang, Shengsong Gou, Yuling Peng, Rui Wei, Da Jia, Yuan Wang, Shangbang Gao, Yan Zhang

PLoS Biol. 2023 Jul; 21(7): e3002165. Published online 2023 Jul 11. doi: 10.1371/journal.pbio.3002165

PMCID:: PMC10335676

Abstract Article PDF–2.2M

Select item 101015006.

The active zone protein Clarinet regulates synaptic sorting of ATG-9 and presynaptic autophagy

Zhao Xuan, Sisi Yang, Benjamin Clark, Sarah E. Hill, Laura Manning, Daniel A. Colón-Ramos

PLoS Biol. 2023 Apr; 21(4): e3002030. Published online 2023 Apr 13. doi: 10.1371/journal.pbio.3002030

PMCID:: PMC10101500

Abstract Article PDF–4.4M

Select item 98099487.

SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity

Chiao-Yin Lim, Huan-Ting Lin, Caroline Kumsta, Tzu-Chiao Lu, Feng-Yung Wang, Yun-Hsuan Kang, Malene Hansen, Tsui-Ting Ching, Ao-Lin Hsu

Autophagy. 2023; 19(1): 224–240. Published online 2022 May 3. doi: 10.1080/15548627.2022.2068267

PMCID:: PMC9809948

Abstract Article PDF–4.7M

Select item 92984308.

Transmembrane protein ATG-9 links presynaptic autophagy with the synaptic vesicle cycle

Sisi Yang, Daniel A. Colón-Ramos

Autophagy. 2022; 18(7): 1746–1747. Published online 2022 Mar 29. doi: 10.1080/15548627.2022.2049151

PMCID:: PMC9298430

Abstract Article PDF–969K

Select item 90170689.

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

Sisi Yang, Daehun Park, Laura Manning, Sarah E. Hill, Mian Cao, Zhao Xuan, Ian Gonzalez, Yongming Dong, Benjamin Clark, Lin Shao, Ifechukwu Okeke, Agustin Almoril-Porras, Jihong Bai, Pietro De Camilli, Daniel A. Colón-Ramos

Neuron. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: Neuron. 2022 Mar 2; 110(5): 824–840.e10. Published online 2022 Jan 21. doi: 10.1016/j.neuron.2021.12.031

PMCID:: PMC9017068

Abstract Article PDF–3.3M

Select item 860502510.

The autophagy protein ATG9A enables lipid mobilization from lipid droplets

Elodie Mailler, Carlos M. Guardia, Xiaofei Bai, Michal Jarnik, Chad D. Williamson, Yan Li, Nunziata Maio, Andy Golden, Juan S. Bonifacino

Nat Commun. 2021; 12: 6750. Published online 2021 Nov 19. doi: 10.1038/s41467-021-26999-x

PMCID:: PMC8605025

Abstract Article PDF–16M

Select item 800402111.

Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans

Georgios Konstantinidis, Nektarios Tavernarakis

Cells. 2021 Mar; 10(3): 694. Published online 2021 Mar 21. doi: 10.3390/cells10030694

PMCID:: PMC8004021

Abstract Article PDF–1.0M

Select item 653428712.

Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans

Hyemin Min, Yong-Uk Lee, Yhong-Hee Shim, Ichiro Kawasaki

PLoS Genet. 2019 May; 15(5): e1008150. Published online 2019 May 24. doi: 10.1371/journal.pgen.1008150

PMCID:: PMC6534287

Abstract Article PDF–4.7M

Select item 621659013.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 564018114.

The recycling endosome protein RAB-10 promotes autophagic flux and localization of the transmembrane protein ATG-9

N. J. Palmisano, N. Rosario, M. Wysocki, M. Hong, B. Grant, A. Meléndez

Autophagy. 2017; 13(10): 1742–1753. Published online 2017 Sep 5. doi: 10.1080/15548627.2017.1356976

PMCID:: PMC5640181

Abstract Article PDF–1.2M

Select item 549447415.

Molecular definitions of autophagy and related processes

Lorenzo Galluzzi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Francesco Cecconi, Augustine M Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Jayanta Debnath, Vojo Deretic, Ivan Dikic, Eeva‐Liisa Eskelinen, Gian Maria Fimia, Simone Fulda, David A Gewirtz, Douglas R Green, Malene Hansen, J Wade Harper, Marja Jäättelä, Terje Johansen, Gabor Juhasz, Alec C Kimmelman, Claudine Kraft, Nicholas T Ktistakis, Sharad Kumar, Beth Levine, Carlos Lopez‐Otin, Frank Madeo, Sascha Martens, Jennifer Martinez, Alicia Melendez, Noboru Mizushima, Christian Münz, Leon O Murphy, Josef M Penninger, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Laura Santambrogio, Luca Scorrano, Anna Katharina Simon, Hans‐Uwe Simon, Anne Simonsen, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Guido Kroemer

EMBO J. 2017 Jul 3; 36(13): 1811–1836. Published online 2017 Jun 8. doi: 10.15252/embj.201796697