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Select item 103353981.

Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells

Kanako Iwasaki, Benjamin Lalani, Jiho Kahng, Priscila Carapeto, Stephanie Sanjines, Francesko Hela, Cristian Abarca, Tadataka Tsuji, Justin Darcy, Andrzej Bartke, Yu-Hua Tseng, Rohit N. Kulkarni, Cristina Aguayo-Mazzucato

Front Endocrinol (Lausanne) 2023; 14: 1203534. Published online 2023 Jun 27. doi: 10.3389/fendo.2023.1203534

PMCID:: PMC10335398

Abstract Article PDF–2.2M

Select item 100914852.

Pituitary Stem Cell Regulation by Zeb2 and BMP Signaling

Amanda H Winningham, Sally A Camper

Endocrinology. 2023 Mar; 164(3): bqad016. Published online 2023 Jan 23. doi: 10.1210/endocr/bqad016

PMCID:: PMC10091485

Abstract Article

Select item 98517463.

Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man

Hironori Bando, Michelle L Brinkmeier, Frederic Castinetti, Qing Fang, Mi-Sun Lee, Alexandru Saveanu, Frédérique Albarel, Clémentine Dupuis, Thierry Brue, Sally A Camper

Hum Mol Genet. 2023 Feb 1; 32(3): 367–385. Published online 2022 Aug 11. doi: 10.1093/hmg/ddac192

PMCID:: PMC9851746

Abstract Article PDF–3.5M

Select item 92501364.

Transient early life growth hormone exposure permanently alters brain, muscle, liver, macrophage, and adipocyte status in long‐lived Ames dwarf mice

Xinna Li, Madaline McPherson, Mary Hager, Yimin Fang, Andrzej Bartke, Richard A. Miller

FASEB J. 2022 Jul; 36(7): e22394. Published online 2022 Jun 15. doi: 10.1096/fj.202200143R

PMCID:: PMC9250136

Abstract Article PDF–4.4M

Select item 80169025.

Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans

Angelica Gualtieri, Nikolina Kyprianou, Louise C. Gregory, Maria Lillina Vignola, James G. Nicholson, Rachael Tan, Shin-ichi Inoue, Valeria Scagliotti, Pedro Casado, James Blackburn, Fernando Abollo-Jimenez, Eugenia Marinelli, Rachael E. J. Besser, Wolfgang Högler, I. Karen Temple, Justin H. Davies, Andrey Gagunashvili, Iain C.A.F. Robinson, Sally A. Camper, Shannon W. Davis, Pedro R. Cutillas, Evelien F. Gevers, Yoko Aoki, Mehul T. Dattani, Carles Gaston-Massuet

Nat Commun. 2021; 12: 2028. Published online 2021 Apr 1. doi: 10.1038/s41467-021-21712-4

PMCID:: PMC8016902

Abstract Article PDF–15M

Select item 79024446.

Skeletal muscle RBM3 expression is associated with extended lifespan in Ames Dwarf and calorie restricted mice

Zachary R. Hettinger, Amy L. Confides, Peter W. Vanderklish, Silvana Sidhom, Michal M. Masternak, Esther E. Dupont-Versteegden

Exp Gerontol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Exp Gerontol. 2021 Apr; 146: 111214. Published online 2020 Dec 30. doi: 10.1016/j.exger.2020.111214

PMCID:: PMC7902444

Abstract Article PDF–414K

Select item 74100637.

Rathke’s cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors

Michelle L. Brinkmeier, Hironori Bando, Adriana C. Camarano, Shingo Fujio, Koji Yoshimoto, Flávio S.J. de Souza, Sally A. Camper

J Clin Invest. 2020 Aug 3; 130(8): 4501–4515. Published online 2020 Jul 20. doi: 10.1172/JCI136745

PMCID:: PMC7410063

Abstract Article PDF–25M

Select item 70297778.

PROP1-Dependent Retinoic Acid Signaling Regulates Developmental Pituitary Morphogenesis and Hormone Expression

Leonard Y M Cheung, Sally A Camper

Endocrinology. 2020 Feb; 161(2): bqaa002. Published online 2020 Jan 8. doi: 10.1210/endocr/bqaa002

PMCID:: PMC7029777

Abstract Article

Select item 70257159.

Primordial follicle reserve, DNA damage and macrophage infiltration in the ovaries of the long-living Ames dwarf mice

Tatiana Dandolini Saccon, Monique Tomazele Rovani, Driele Neske Garcia, Rafael Gianella Mondadori, Luis Augusto Xavier Cruz, Carlos Castilho Barros, Andrzej Bartke, Michal M Masternak, Augusto Schneider

Exp Gerontol. Author manuscript; available in PMC 2021 Apr 1.

Published in final edited form as: Exp Gerontol. 2020 Apr; 132: 110851. Published online 2020 Jan 25. doi: 10.1016/j.exger.2020.110851

PMCID:: PMC7025715

Abstract Article PDF–942K

Select item 693989010.

Genetic variation in thyroid folliculogenesis influences susceptibility to hypothyroidism-induced hearing impairment

Amanda H. Mortensen, Qing Fang, Michelle T. Fleming, Thomas J. Jones, Alexandre Z. Daly, Kenneth R. Johnson, Sally A. Camper

Mamm Genome. Author manuscript; available in PMC 2020 Jan 2.

Published in final edited form as: Mamm Genome. 2019 Feb; 30(1-2): 5–22. Published online 2019 Feb 18. doi: 10.1007/s00335-019-09792-6

PMCID:: PMC6939890

Abstract Article PDF–2.4M

Select item 645693011.

Premature Expression of FOXO1 in Developing Mouse Pituitary Results in Anterior Lobe Hypoplasia

Caitlin E Stallings, Buffy S Ellsworth

Endocrinology. 2018 Aug; 159(8): 2891–2904. Published online 2018 May 22. doi: 10.1210/en.2018-00107

PMCID:: PMC6456930

Abstract Article

Select item 643280012.

The hippocampus of Ames dwarf mice exhibits enhanced antioxidative defenses following kainic acid-induced oxidative stress

Sunita Sharma, Sharlene Rakoczy, Kristine Dahlheimer, Holly Brown-Borg

Exp Gerontol. Author manuscript; available in PMC 2019 Mar 25.

Published in final edited form as: Exp Gerontol. 2010 Dec; 45(12): 936–949. Published online 2010 Sep 8. doi: 10.1016/j.exger.2010.08.013

PMCID:: PMC6432800

Abstract Article PDF–2.3M

Select item 628794513.

A whole lifespan mouse multi-tissue DNA methylation clock

Margarita V Meer, Dmitriy I Podolskiy, Alexander Tyshkovskiy, Vadim N Gladyshev

eLife. 2018; 7: e40675. Published online 2018 Nov 14. doi: 10.7554/eLife.40675

PMCID:: PMC6287945

Abstract Article PDF–2.0M

Select item 628127314.

Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity

Oliver Hahn, Thomas M. Stubbs, Wolf Reik, Sebastian Grönke, Andreas Beyer, Linda Partridge

PLoS Genet. 2018 Nov; 14(11): e1007766. Published online 2018 Nov 21. doi: 10.1371/journal.pgen.1007766

PMCID:: PMC6281273

Abstract Article PDF–2.6M

Select item 628097415.

Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans

Ryan O. Walters, Esperanza Arias, Antonio Diaz, Emmanuel S. Burgos, Fangxia Guan, Simoni Tiano, Kai Mao, Cara L. Green, Yungping Qiu, Hardik Shah, Donghai Wang, Adam D. Hudgins, Tahmineh Tabrizian, Valeria Tosti, David Shechter, Luigi Fontana, Irwin J. Kurland, Nir Barzilai, Ana Maria Cuervo, Daniel E.L. Promislow, Derek M. Huffman

Cell Rep. Author manuscript; available in PMC 2018 Dec 5.

Published in final edited form as: Cell Rep. 2018 Oct 16; 25(3): 663–676.e6. doi: 10.1016/j.celrep.2018.09.065

PMCID:: PMC6280974

Abstract Article PDF–2.4M

Select item 580875516.

Cathepsin B regulates hepatic lipid metabolism by cleaving liver fatty acid–binding protein

Simeon Thibeaux, Shaila Siddiqi, Olga Zhelyabovska, Faisal Moinuddin, Michal M. Masternak, Shadab A. Siddiqi

J Biol Chem. 2018 Feb 9; 293(6): 1910–1923. Published online 2017 Dec 19. doi: 10.1074/jbc.M117.778365

PMCID:: PMC5808755

Abstract Article PDF–2.2M

Select item 572224717.

Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

Christopher Hine, Hyo-Jeong Kim, Yan Zhu, Eylul Harputlugil, Alban Longchamp, Marina Souza Matos, Preeti Ramadoss, Kevin Bauerle, Lear Brace, John M. Asara, C. Keith Ozaki, Sheue-yann Cheng, Subhankar Singha, Kyo Han Ahn, Alec Kimmelman, Ffolliott M. Fisher, Pavlos Pissios, Dominic J. Withers, Colin Selman, Rui Wang, Kelvin Yen, Valter D. Longo, Pinchas Cohen, Andrzej Bartke, John J. Kopchick, Richard Miller, Anthony N. Hollenberg, James R. Mitchell

Cell Metab. 2017 Jun 6; 25(6): 1320–1333.e5. doi: 10.1016/j.cmet.2017.05.003

PMCID:: PMC5722247

Abstract Article

Select item 551935418.

A dual agonist of farnesoid X receptor (FXR) and the G protein–coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice

Xiaoxin X. Wang, Yuhuan Luo, Dong Wang, Luciano Adorini, Mark Pruzanski, Evgenia Dobrinskikh, Moshe Levi

J Biol Chem. 2017 Jul 21; 292(29): 12018–12024. Published online 2017 Jun 8. doi: 10.1074/jbc.C117.794982

PMCID:: PMC5519354

Abstract Article PDF–589K

Select item 551557519.

Longevity is impacted by growth hormone action during early postnatal period

Liou Y Sun, Yimin Fang, Amit Patki, Jacob JE Koopman, David B Allison, Cristal M Hill, Michal M Masternak, Justin Darcy, Jian Wang, Samuel McFadden, Andrzej Bartke

eLife. 2017; 6: e24059. Published online 2017 Jul 4. doi: 10.7554/eLife.24059

PMCID:: PMC5515575

Abstract Article PDF–5.0M

Select item 539738320.

Ovarian aging and the activation of the primordial follicle reserve in the long-lived Ames dwarf and the short-lived bGH transgenic mice

Tatiana D. Saccon, Fabiana Moreira, Luis A. Cruz, Rafael G. Mondadori, Yimin Fang, Carlos C. Barros, L. Spinel, A. Bartke, Michal M. Masternak, A. Schneider

Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Nov 5.

Published in final edited form as: Mol Cell Endocrinol. 2017 Nov 5; 455: 23–32. Published online 2016 Oct 19. doi: 10.1016/j.mce.2016.10.015

PMCID:: PMC5397383

Abstract Article PDF–2.6M

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