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Select item 106422361.

Neural control of redox response and microbiota-triggered inflammation in Drosophila gut

Naoyuki Fuse, Haruka Hashiba, Kentaro Ishibashi, Takuro Suzuki, Quang-Dat Nguyen, Kiho Fujii, Wakako Ikeda-Ohtsubo, Haruki Kitazawa, Hiromu Tanimoto, Shoichiro Kurata

Front Immunol. 2023; 14: 1268611. Published online 2023 Oct 26. doi: 10.3389/fimmu.2023.1268611

PMCID:: PMC10642236

Abstract Article PDF–2.3M

Select item 104951092.

Fat body-specific reduction of CTPS alleviates HFD-induced obesity

Jingnan Liu, Yuanbing Zhang, Qiao-Qi Wang, Youfang Zhou, Ji-Long Liu

eLife. 2023; 12: e85293. Published online 2023 Sep 11. doi: 10.7554/eLife.85293

PMCID:: PMC10495109

Abstract Article PDF–13M

Select item 104425443.

A nerve-wracking buzz: lessons from Drosophila models of peripheral neuropathy and axon degeneration

Martha R. C. Bhattacharya

Front Aging Neurosci. 2023; 15: 1166146. Published online 2023 Aug 8. doi: 10.3389/fnagi.2023.1166146

PMCID:: PMC10442544

Abstract Article PDF–841K

Select item 103226904.

Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency

Yi Zhu, Amanda G. Lobato, Adriana P. Rebelo, Tijana Canic, Natalie Ortiz-Vega, Xianzun Tao, Sheyum Syed, Christopher Yanick, Mario Saporta, Michael Shy, Riccardo Perfetti, Shoshana Shendelman, Stephan Züchner, R. Grace Zhai

JCI Insight. 2023 May 22; 8(10): e164954. Published online 2023 May 22. doi: 10.1172/jci.insight.164954

PMCID:: PMC10322690

Abstract Article PDF–14M

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 99561306.

Circulating fructose regulates a germline stem cell increase via gustatory receptor–mediated gut hormone secretion in mated Drosophila

Ryo Hoshino, Hiroko Sano, Yuto Yoshinari, Takashi Nishimura, Ryusuke Niwa

Sci Adv. 2023 Feb; 9(8): eadd5551. Published online 2023 Feb 24. doi: 10.1126/sciadv.add5551

PMCID:: PMC9956130

Abstract Article PDF–1.8M

Select item 97332797.

The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors

Llewellyn Green, Marta Coronado-Zamora, Santiago Radío, Gabriel E. Rech, Judit Salces-Ortiz, Josefa González

BMC Biol. 2022; 20: 275. Published online 2022 Dec 8. doi: 10.1186/s12915-022-01479-w

PMCID:: PMC9733279

Abstract Article PDF–3.8M

Select item 92233048.

The polyol pathway is an evolutionarily conserved system for sensing glucose uptake

Hiroko Sano, Akira Nakamura, Mariko Yamane, Hitoshi Niwa, Takashi Nishimura, Kimi Araki, Kazumasa Takemoto, Kei-ichiro Ishiguro, Hiroki Aoki, Yuzuru Kato, Masayasu Kojima

PLoS Biol. 2022 Jun; 20(6): e3001678. Published online 2022 Jun 10. doi: 10.1371/journal.pbio.3001678

PMCID:: PMC9223304

Abstract Article PDF–3.1M

Select item 83535999.

BIALLELIC MUTATIONS IN SORD CAUSE A COMMON AND POTENTIALLY TREATABLE HEREDITARY NEUROPATHY WITH IMPLICATIONS FOR DIABETES

Andrea Cortese, Yi Zhu, Adriana Rebelo, Sara Negri, Steve Courel, Lisa Abreu, Chelsea J Bacon, Yunhong Bai, Dana M Bis-Brewer, Enrico Bugiardini, Elena Buglo, Matt C Danzi, Shawna ME Feely, Alkyoni A Fragkouli, Nourelhoda A Haridy, Inherited Neuropathy Consortium, Rosario Isasi, Alaa Khan, Matilde Laurà, Stefania Magri, Menelaos Pipis, Chiara Pisciotta, Eric Powell, Alexander M Rossor, Janet Sowden, Stefano Tozza, Jana Vandrovcova, Julia Dallman, Elena Grignani, Enrico Marchioni, Steven S Scherer, Beisha Tang, Zhiqiang Lin, Abdullah Al-Ajmi, Rebecca Schüle, Matthis Synofzik, Thierry Maisonobe, Tanya Stojkovic, Michaela Auer-Grumbach, Mohamed A Abdelhamed, Sherifa A. Hamed, Ruxu Zhang, Fiore Manganelli, Lucio Santoro, Paola Saveri, Franco Taroni, Davide Pareyson, Henry Houlden, David N Herrmann, Mary M Reilly, Michael E Shy, Grace Zhai, Stephan Zuchner

Nat Genet. Author manuscript; available in PMC 2021 Aug 10.

Published in final edited form as: Nat Genet. 2020 May; 52(5): 473–481. Published online 2020 May 4. doi: 10.1038/s41588-020-0615-4

PMCID:: PMC8353599

Abstract Article PDF–2.5M

Select item 788512010.

Wolbachia and Virus Alter the Host Transcriptome at the Interface of Nucleotide Metabolism Pathways

Amelia R. I. Lindsey, Tamanash Bhattacharya, Richard W. Hardy, Irene L. G. Newton

mBio. 2021 Jan-Feb; 12(1): e03472-20. Published online 2021 Feb 9. doi: 10.1128/mBio.03472-20

PMCID:: PMC7885120

Abstract Article PDF–3.5M

Select item 758298811.

Recent Advances in Drosophila Models of Charcot-Marie-Tooth Disease

Fukiko Kitani-Morii, Yu-ichi Noto

Int J Mol Sci. 2020 Oct; 21(19): 7419. Published online 2020 Oct 8. doi: 10.3390/ijms21197419

PMCID:: PMC7582988

Abstract Article PDF–620K

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 633882713.

Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy

Hamutal Arbel, Sumanta Basu, William W. Fisher, Ann S. Hammonds, Kenneth H. Wan, Soo Park, Richard Weiszmann, Benjamin W. Booth, Soile V. Keranen, Clara Henriquez, Omid Shams Solari, Peter J. Bickel, Mark D. Biggin, Susan E. Celniker, James B. Brown

Proc Natl Acad Sci U S A. 2019 Jan 15; 116(3): 900–908. Published online 2018 Dec 31. doi: 10.1073/pnas.1808833115

PMCID:: PMC6338827

Abstract Article PDF–1.5M

Select item 597943114.

Aging and Intermittent Fasting Impact on Transcriptional Regulation and Physiological Responses of Adult Drosophila Neuronal and Muscle Tissues

Sharon Zhang, Eric P. Ratliff, Brandon Molina, Nadja El-Mecharrafie, Jessica Mastroianni, Roxanne W. Kotzebue, Madhulika Achal, Ruth E. Mauntz, Arysa Gonzalez, Ayeh Barekat, William A. Bray, Andrew M. Macias, Daniel Daugherty, Greg L. Harris, Robert A. Edwards, Kim D. Finley

Int J Mol Sci. 2018 Apr; 19(4): 1140. Published online 2018 Apr 10. doi: 10.3390/ijms19041140

PMCID:: PMC5979431

Abstract Article PDF–28M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 512686417.

Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster

Punita Juneja, Andrew Quinn, Francis M. Jiggins

BMC Genomics. 2016; 17: 981. Published online 2016 Nov 28. doi: 10.1186/s12864-016-3333-7

PMCID:: PMC5126864

Abstract Article PDF–1.1M

Select item 482595518.

Sir2 Acts through Hepatocyte Nuclear Factor 4 to maintain insulin Signaling and Metabolic Homeostasis in Drosophila

Rebecca A. S. Palu, Carl S. Thummel

PLoS Genet. 2016 Apr; 12(4): e1005978. Published online 2016 Apr 8. doi: 10.1371/journal.pgen.1005978

PMCID:: PMC4825955

Abstract Article PDF–1.8M

Select item 478811619.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 452833020.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

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