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Select item 109578971.

An evolutionary mechanism to assimilate new nutrient sensors into the mTORC1 pathway

Grace Y. Liu, Patrick Jouandin, Raymond E. Bahng, Norbert Perrimon, David M. Sabatini

Nat Commun. 2024; 15: 2517. Published online 2024 Mar 21. doi: 10.1038/s41467-024-46680-3

PMCID:: PMC10957897

Abstract Article PDF–2.0M

Select item 101127102.

Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila

Xin Gu, Patrick Jouandin, Pranav V. Lalgudi, Rich Binari, Max L. Valenstein, Michael A. Reid, Annamarie E. Allen, Nolan Kamitaki, Jason W. Locasale, Norbert Perrimon, David M. Sabatini

Nature. Author manuscript; available in PMC 2023 Apr 18.

Published in final edited form as: Nature. 2022 Aug; 608(7921): 209–216. Published online 2022 Jul 20. doi: 10.1038/s41586-022-04960-2

Correction in:: Nature. 2022 Sep 13

PMCID:: PMC10112710

Abstract Article PDF–4.7M

Select item 99104873.

Wdr59 promotes or inhibits TORC1 activity depending on cellular context

Yingbiao Zhang, Chun-Yuan Ting, Shu Yang, John Reich, Karenne Fru, Mary A. Lilly

Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2212330120. Published online 2022 Dec 28. doi: 10.1073/pnas.2212330120

PMCID:: PMC9910487

Abstract Article PDF–7.5M

Select item 92396804.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 80791505.

Methionine restriction breaks obligatory coupling of cell proliferation and death by an oncogene Src in Drosophila

Hiroshi Nishida, Morihiro Okada, Lynna Yang, Tomomi Takano, Sho Tabata, Tomoyoshi Soga, Diana M Ho, Jongkyeong Chung, Yasuhiro Minami, Sa Kan Yoo

eLife. 2021; 10: e59809. Published online 2021 Apr 27. doi: 10.7554/eLife.59809

PMCID:: PMC8079150

Abstract Article PDF–6.6M

Select item 79921876.

Epigenetic Regulation of Drosophila Germline Stem Cell Maintenance and Differentiation

Velinda Vidaurre, Xin Chen

Dev Biol. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Dev Biol. 2021 May; 473: 105–118. Published online 2021 Feb 18. doi: 10.1016/j.ydbio.2021.02.003

PMCID:: PMC7992187

Abstract Article PDF–1.0M

Select item 57078057.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890028.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 48642419.

The GATOR2 Component Wdr24 Regulates TORC1 Activity and Lysosome Function

Weili Cai, Youheng Wei, Michal Jarnik, John Reich, Mary A. Lilly

PLoS Genet. 2016 May; 12(5): e1006036. Published online 2016 May 11. doi: 10.1371/journal.pgen.1006036

PMCID:: PMC4864241

Abstract Article PDF–6.9M

Select item 452833010.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832911.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 435288712.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 432874513.

The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle

Maria L Spletter, Christiane Barz, Assa Yeroslaviz, Cornelia Schönbauer, Irene R S Ferreira, Mihail Sarov, Daniel Gerlach, Alexander Stark, Bianca H Habermann, Frank Schnorrer

EMBO Rep. 2015 Feb; 16(2): 178–191. Published online 2014 Dec 22. doi: 10.15252/embr.201439791

PMCID:: PMC4328745

Abstract Article PDF–4.8M

Select item 372865414.

A tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

Liron Bar-Peled, Lynne Chantranupong, Andrew D. Cherniack, Walter W. Chen, Kathleen A. Ottina, Brian C. Grabiner, Eric D. Spear, Scott L. Carter, Matthew Meyerson, David M. Sabatini

Science. Author manuscript; available in PMC 2013 Jul 31.

Published in final edited form as: Science. 2013 May 31; 340(6136): 1100–1106. doi: 10.1126/science.1232044

PMCID:: PMC3728654

Abstract Article PDF–2.5M

Select item 353067715.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946716.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 310883717.

A Conserved Coatomer-related Complex Containing Sec13 and Seh1 Dynamically Associates With the Vacuole in Saccharomyces cerevisiae

Svetlana Dokudovskaya, Francois Waharte, Avner Schlessinger, Ursula Pieper, Damien P. Devos, Ileana M. Cristea, Rosemary Williams, Jean Salamero, Brian T. Chait, Andrej Sali, Mark C. Field, Michael P. Rout, Catherine Dargemont

Mol Cell Proteomics. 2011 Jun; 10(6): M110.006478. Published online 2011 Mar 31. doi: 10.1074/mcp.M110.006478

PMCID:: PMC3108837

Abstract Article PDF–2.7M

Select item 304044118.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

Select item 282505319.

Sequence Finishing and Mapping of Drosophila melanogaster Heterochromatin

Roger A. Hoskins, Joseph W. Carlson, Cameron Kennedy, David Acevedo, Martha Evans-Holm, Erwin Frise, Kenneth H. Wan, Soo Park, Maria Mendez-Lago, Fabrizio Rossi, Alfredo Villasante, Patrizio Dimitri, Gary H. Karpen, Susan E. Celniker

Science. Author manuscript; available in PMC 2010 Feb 19.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1625–1628. doi: 10.1126/science.1139816

PMCID:: PMC2825053

Abstract Article PDF–858K

Select item 281928020.

The Release 5.1 Annotation of Drosophila melanogaster Heterochromatin

Christopher D. Smith, ShengQiang Shu, Christopher J. Mungall, Gary H. Karpen

Science. Author manuscript; available in PMC 2010 Feb 10.

Published in final edited form as: Science. 2007 Jun 15; 316(5831): 1586. doi: 10.1126/science.1139815

Correction in:: volume 317 on page 1325

PMCID:: PMC2819280

Abstract Article PDF–1.3M

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