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Select item 101655411.

Systematic analysis of YFP traps reveals common mRNA/protein discordance in neural tissues

Joshua S. Titlow, Maria Kiourlappou, Ana Palanca, Jeffrey Y. Lee, Dalia S. Gala, Darragh Ennis, Joyce J.S. Yu, Florence L. Young, David Miguel Susano Pinto, Sam Garforth, Helena S. Francis, Finn Strivens, Hugh Mulvey, Alex Dallman-Porter, Staci Thornton, Diana Arman, Marissa J. Millard, Aino I. Järvelin, Mary Kay Thompson, Martin Sargent, Ilias Kounatidis, Richard M. Parton, Stephen Taylor, Ilan Davis

J Cell Biol. 2023 Jun 5; 222(6): e202205129. Published online 2023 May 5. doi: 10.1083/jcb.202205129

PMCID:: PMC10165541

Abstract Article PDF–8.4M

Select item 101645912.

RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system

Filip Pekovic, Christiane Rammelt, Jana Kubíková, Jutta Metz, Mandy Jeske, Elmar Wahle

Nucleic Acids Res. 2023 May 8; 51(8): 3950–3970. Published online 2023 Mar 23. doi: 10.1093/nar/gkad159

PMCID:: PMC10164591

Abstract Article PDF–4.6M

Select item 101057363.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 94184434.

A conserved domain of Drosophila RNA-binding protein Pumilio interacts with multiple CCR4–NOT deadenylase complex subunits to repress target mRNAs

Rebecca J. Haugen, René M. Arvola, Robert P. Connacher, Richard T. Roden, Aaron C. Goldstrohm

J Biol Chem. 2022 Sep; 298(9): 102270. Published online 2022 Jul 16. doi: 10.1016/j.jbc.2022.102270

PMCID:: PMC9418443

Abstract Article PDF–2.6M

Select item 88632975.

Transcriptional Regulators of Ecdysteroid Biosynthetic Enzymes and Their Roles in Insect Development

Takumi Kamiyama, Ryusuke Niwa

Front Physiol. 2022; 13: 823418. Published online 2022 Feb 8. doi: 10.3389/fphys.2022.823418

PMCID:: PMC8863297

Abstract Article PDF–1.4M

Select item 86644866.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 73906267.

Silencing of CCR4-NOT complex subunits affects heart structure and function

Lisa Elmén, Claudia B. Volpato, Anaïs Kervadec, Santiago Pineda, Sreehari Kalvakuri, Nakissa N. Alayari, Luisa Foco, Peter P. Pramstaller, Karen Ocorr, Alessandra Rossini, Anthony Cammarato, Alexandre R. Colas, Andrew A. Hicks, Rolf Bodmer

Dis Model Mech. 2020 Jul 1; 13(7): dmm044727. Published online 2020 Jul 20. doi: 10.1242/dmm.044727

PMCID:: PMC7390626

Abstract Article

Select item 70389328.

Unique repression domains of Pumilio utilize deadenylation and decapping factors to accelerate destruction of target mRNAs

René M Arvola, Chung-Te Chang, Joseph P Buytendorp, Yevgen Levdansky, Eugene Valkov, Peter L Freddolino, Aaron C Goldstrohm

Nucleic Acids Res. 2020 Feb 28; 48(4): 1843–1871. Published online 2019 Dec 21. doi: 10.1093/nar/gkz1187

PMCID:: PMC7038932

Abstract Article PDF–8.8M

Select item 69615789.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 689046510.

Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing

Lauren E Foley, Jinli Ling, Radhika Joshi, Naveh Evantal, Sebastian Kadener, Patrick Emery

eLife. 2019; 8: e50063. Published online 2019 Nov 8. doi: 10.7554/eLife.50063

PMCID:: PMC6890465

Abstract Article PDF–3.0M

Select item 679686211.

Defining an evolutionarily conserved role of GW182 in circular RNA degradation

Ruirui Jia, Mei-Sheng Xiao, Zhengguo Li, Ge Shan, Chuan Huang

Cell Discov. 2019; 5: 45. Published online 2019 Sep 17. doi: 10.1038/s41421-019-0113-y

PMCID:: PMC6796862

Article PDF–908K

Select item 679619412.

Defining the expression of piRNA and transposable elements in Drosophila ovarian germline stem cells and somatic support cells

Benjamin Story, Xing Ma, Kazue Ishihara, Hua Li, Kathryn Hall, Allison Peak, Perera Anoja, Jungeun Park, Jeff Haug, Marco Blanchette, Ting Xie

Life Sci Alliance. 2019 Oct; 2(5): e201800211. Published online 2019 Oct 16. doi: 10.26508/lsa.201800211

PMCID:: PMC6796194

Abstract Article PDF–3.3M

Select item 664888613.

Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression

Vincenzo Ruscica, Praveen Bawankar, Daniel Peter, Sigrun Helms, Cátia Igreja, Elisa Izaurralde

Nucleic Acids Res. 2019 Jul 26; 47(13): 7035–7048. Published online 2019 May 22. doi: 10.1093/nar/gkz429

PMCID:: PMC6648886

Abstract Article PDF–2.8M

Select item 643120914.

PERIOD-controlled deadenylation of the timeless transcript in the Drosophila circadian clock

Brigitte Grima, Christian Papin, Béatrice Martin, Elisabeth Chélot, Prishila Ponien, Eric Jacquet, François Rouyer

Proc Natl Acad Sci U S A. 2019 Mar 19; 116(12): 5721–5726. Published online 2019 Mar 4. doi: 10.1073/pnas.1814418116

PMCID:: PMC6431209

Abstract Article PDF–1.1M

Select item 639246015.

Inhibiting transcription in cultured metazoan cells with actinomycin D to monitor mRNA turnover

Wi S. Lai, Rene M. Arvola, Aaron C. Goldstrohm, Perry J. Blackshear

Methods. Author manuscript; available in PMC 2020 Feb 15.

Published in final edited form as: Methods. 2019 Feb 15; 155: 77–87. Published online 2019 Jan 6. doi: 10.1016/j.ymeth.2019.01.003

PMCID:: PMC6392460

Abstract Article PDF–687K

Select item 632825416.

Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3′ UTRs

Pooja Flora, Siu Wah Wong-Deyrup, Elliot Todd Martin, Ryan J. Palumbo, Mohamad Nasrallah, Andrew Oligney, Patrick Blatt, Dhruv Patel, Gabriele Fuchs, Prashanth Rangan

Cell Rep. Author manuscript; available in PMC 2019 Jan 10.

Published in final edited form as: Cell Rep. 2018 Dec 26; 25(13): 3828–3843.e9. doi: 10.1016/j.celrep.2018.12.007

PMCID:: PMC6328254

Abstract Article PDF–3.3M

Select item 629516217.

Multilayered gene control drives timely exit from the stem cell state in uncommitted progenitors during Drosophila asymmetric neural stem cell division

Hideyuki Komori, Krista L. Golden, Taeko Kobayashi, Ryoichiro Kageyama, Cheng-Yu Lee

Genes Dev. 2018 Dec 1; 32(23-24): 1550–1561. doi: 10.1101/gad.320333.118

PMCID:: PMC6295162

Abstract Article PDF–7.1M

Select item 616849718.

LOTUS domain protein MARF1 binds CCR4-NOT deadenylase complex to post-transcriptionally regulate gene expression in oocytes

Li Zhu, Suresh K. Kandasamy, Susan E. Liao, Ryuya Fukunaga

Nat Commun. 2018; 9: 4031. Published online 2018 Oct 2. doi: 10.1038/s41467-018-06404-w

Correction in:: Nat Commun. 2019; 10: 1074.

PMCID:: PMC6168497

Abstract Article PDF–3.4M

Select item 610929419.

The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models

Carmen Vicente, Rocco Stirparo, Sofie Demeyer, Charles E. de Bock, Olga Gielen, Mardelle Atkins, Jiekun Yan, Georg Halder, Bassem A. Hassan, Jan Cools

J Hematol Oncol. 2018; 11: 108. Published online 2018 Aug 25. doi: 10.1186/s13045-018-0650-0

PMCID:: PMC6109294

Abstract Article PDF–3.1M

Select item 570780520.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

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