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Select item 102049571.

TORC1 regulation of dendrite regrowth after pruning is linked to actin and exocytosis

Neeraja Sanal, Lorena Keding, Ulrike Gigengack, Esther Michalke, Sebastian Rumpf

PLoS Genet. 2023 May; 19(5): e1010526. Published online 2023 May 11. doi: 10.1371/journal.pgen.1010526

PMCID:: PMC10204957

Abstract Article PDF–4.4M

Select item 99975702.

NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development

Joshua Hudson, Sayantanee Paul, Alexey Veraksa, Amin Ghabrial, Kieran F Harvey, Carole Poon

G3 (Bethesda) 2023 Mar; 13(3): jkad013. Published online 2023 Jan 19. doi: 10.1093/g3journal/jkad013

PMCID:: PMC9997570

Abstract Article PDF–798K

Select item 93364953.

Chromatin and transcriptomic profiling uncover dysregulation of the Tip60 HAT/HDAC2 epigenomic landscape in the neurodegenerative brain

Mariah Beaver, Bhanu Chandra Karisetty, Haolin Zhang, Akanksha Bhatnagar, Ellen Armour, Visha Parmar, Reshma Brown, Merry Xiang, Felice Elefant

Epigenetics. 2022; 17(7): 786–807. Published online 2021 Aug 9. doi: 10.1080/15592294.2021.1959742

PMCID:: PMC9336495

Abstract Article PDF–3.5M

Select item 91967874.

A yeast two-hybrid screening identifies novel Atg8a interactors in Drosophila

Panagiotis Tsapras, Ioannis P. Nezis

Autophagy. 2022; 18(5): 1211–1212. Published online 2022 Feb 28. doi: 10.1080/15548627.2022.2045535

PMCID:: PMC9196787

Abstract Article PDF–370K

Select item 86644865.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86644556.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 85343997.

Drosophila Dendritic Arborisation Neurons: Fantastic Actin Dynamics and Where to Find Them

Lukas Kilo, Tomke Stürner, Gaia Tavosanis, Anna B. Ziegler

Cells. 2021 Oct; 10(10): 2777. Published online 2021 Oct 16. doi: 10.3390/cells10102777

PMCID:: PMC8534399

Abstract Article PDF–2.3M

Select item 84688278.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 80229469.

An RNAi screen of the kinome in epithelial follicle cells of the Drosophila melanogaster ovary reveals genes required for proper germline death and clearance

Diane P V Lebo, Alice Chirn, Jeffrey D Taylor, Andre Levan, Valentina Doerre Torres, Emily Agreda, Sandy B Serizier, Allison K Lord, Victoria K Jenkins, Kimberly McCall

G3 (Bethesda) 2021 Feb; 11(2): jkaa066. Published online 2021 Mar 6. doi: 10.1093/g3journal/jkaa066

PMCID:: PMC8022946

Abstract Article PDF–1.3M

Select item 757659910.

Emerging role of the Hippo pathway in autophagy

Dongying Wang, Jiaxing He, Bingyu Huang, Shanshan Liu, Hongming Zhu, Tianmin Xu

Cell Death Dis. 2020 Oct; 11(10): 880. Published online 2020 Oct 20. doi: 10.1038/s41419-020-03069-6

PMCID:: PMC7576599

Abstract Article PDF–2.3M

Select item 750273811.

Multiplexed conditional genome editing with Cas12a in Drosophila

Fillip Port, Maja Starostecka, Michael Boutros

Proc Natl Acad Sci U S A. 2020 Sep 15; 117(37): 22890–22899. Published online 2020 Aug 25. doi: 10.1073/pnas.2004655117

PMCID:: PMC7502738

Abstract Article PDF–4.5M

Select item 702148712.

Ser/Thr kinase Trc controls neurite outgrowth in Drosophila by modulating microtubule-microtubule sliding

Rosalind Norkett, Urko del Castillo, Wen Lu, Vladimir I Gelfand

eLife. 2020; 9: e52009. Published online 2020 Feb 5. doi: 10.7554/eLife.52009

PMCID:: PMC7021487

Abstract Article PDF–5.9M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 654822714.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 650653915.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 645136216.

Beyond being innervated: the epidermis actively shapes sensory dendritic patterning

Wei-Kang Yang, Cheng-Ting Chien

Open Biol. 2019 Mar; 9(3): 180257. Published online 2019 Mar 27. doi: 10.1098/rsob.180257

PMCID:: PMC6451362

Abstract Article PDF–1.0M

Select item 628129717.

A Hippo-like signalling pathway controls tracheal morphogenesis in Drosophila melanogaster

Carole L. C. Poon, Weijie Liu, Yanjun Song, Marta Gomez, Yavuz Kulaberoglu, Xiaomeng Zhang, Wenjian Xu, Alexey Veraksa, Alexander Hergovich, Amin Ghabrial, Kieran F. Harvey

Dev Cell. Author manuscript; available in PMC 2019 Dec 3.

Published in final edited form as: Dev Cell. 2018 Dec 3; 47(5): 564–575.e5. Published online 2018 Oct 25. doi: 10.1016/j.devcel.2018.09.024

PMCID:: PMC6281297

Abstract Article PDF–2.5M

Select item 607860418.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 593136919.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556