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Select item 115138361.

A candidate loss-of-function variant in SGIP1 causes synaptic dysfunction and recessive parkinsonism

Marianna Decet, Patrick Scott, Sabine Kuenen, Douja Meftah, Jef Swerts, Carles Calatayud, Sandra F. Gallego, Natalie Kaempf, Eliana Nachman, Roman Praschberger, Nils Schoovaerts, Chris C. Tang, David Eidelberg, Samir Al Adawi, Abdullah Al Asmi, Ramachandiran Nandhagopal, Patrik Verstreken

Cell Rep Med. 2024 Oct 15; 5(10): 101749. Published online 2024 Sep 26. doi: 10.1016/j.xcrm.2024.101749

PMCID:: PMC11513836

Abstract Article PDF–7.3M

Select item 114956002.

Tissue-specific knockout in the Drosophila neuromuscular system reveals ESCRT’s role in formation of synapse-derived extracellular vesicles

Xinchen Chen, Sarah Perry, Ziwei Fan, Bei Wang, Elizabeth Loxterkamp, Shuran Wang, Jiayi Hu, Dion Dickman, Chun Han

PLoS Genet. 2024 Oct; 20(10): e1011438. Published online 2024 Oct 10. doi: 10.1371/journal.pgen.1011438

PMCID:: PMC11495600

Abstract Article PDF–5.7M

Select item 114803343.

Histamine synthesis and transport are coupled in axon terminals via a dual quality control system

Lei Peng, Tao Wang

EMBO J. 2024 Oct; 43(20): 4472–4491. Published online 2024 Sep 6. doi: 10.1038/s44318-024-00223-0

PMCID:: PMC11480334

Abstract Article PDF–5.4M

Select item 113373414.

Genetic and molecular analysis of the synaptotagmin family

B. Adolfsen, J.T. Littleton

Cell Mol Life Sci. 2001 Mar; 58(3): 393–402. doi: 10.1007/PL00000865

PMCID:: PMC11337341

Abstract Article PDF–180K

Select item 111133555.

C. elegans RNA-dependent RNA polymerases rrf-1 and ego-1 silence Drosophila transgenes by differing mechanisms

Guowen Duan, Robert B. Saint, Chris A. Helliwell, Carolyn A. Behm, Ming-Bo Wang, Peter M. Waterhouse, Karl H. J. Gordon

Cell Mol Life Sci. 2013 Apr; 70(8): 1469–1481. Published online 2012 Dec 8. doi: 10.1007/s00018-012-1218-8

PMCID:: PMC11113355

Abstract Article PDF–811K

Select item 110787286.

The effects of methylphenidate and atomoxetine on Drosophila brain at single-cell resolution and potential drug repurposing for ADHD treatment

Susu Qu, Xiangyu Zhou, Zhicheng Wang, Yi Wei, Han Zhou, Xinshuang Zhang, Qingjie Zhu, Yanmin Wang, Quanjun Yang, Likun Jiang, Yuan Ma, Yuan Gao, Lei Kong, Li Zhang

Mol Psychiatry. 2024; 29(1): 165–185. Published online 2023 Nov 13. doi: 10.1038/s41380-023-02314-6

PMCID:: PMC11078728

Abstract Article PDF–4.8M

Select item 110607187.

Conditional chemoconnectomics (cCCTomics) as a strategy for efficient and conditional targeting of chemical transmission

Renbo Mao, Jianjun Yu, Bowen Deng, Xihuimin Dai, Yuyao Du, Sujie Du, Wenxia Zhang, Yi Rao

eLife. 2024; 12: RP91927. Published online 2024 Apr 30. doi: 10.7554/eLife.91927

PMCID:: PMC11060718

Abstract Article PDF–4.3M

Select item 109651088.

Comparative genomic analyses reveal evidence for adaptive A-to-I RNA editing in insect Adar gene

Caiqing Zheng, Ling Ma, Fan Song, Li Tian, Wanzhi Cai, Hu Li, Yuange Duan

Epigenetics. 2024; 19(1): 2333665. Published online 2024 Mar 25. doi: 10.1080/15592294.2024.2333665

PMCID:: PMC10965108

Abstract Article PDF–7.0M

Select item 109457689.

Cellular and molecular organization of the Drosophila foregut

Haolong Zhu, William B. Ludington, Allan C. Spradling

Proc Natl Acad Sci U S A. 2024 Mar 12; 121(11): e2318760121. Published online 2024 Mar 5. doi: 10.1073/pnas.2318760121

PMCID:: PMC10945768

Abstract Article PDF–5.0M

Select item 1090770010.

Baf-mediated transcriptional regulation of teashirt is essential for the development of neural progenitor cell lineages

Byung Su Ko, Myeong Hoon Han, Min Jee Kwon, Dong Gon Cha, Yuri Ji, Eun Seo Park, Min Jae Jeon, Somi Kim, Kyeongho Lee, Yoon Ha Choi, Jusung Lee, Monica Torras-Llort, Ki-Jun Yoon, Hyosang Lee, Jong Kyoung Kim, Sung Bae Lee

Exp Mol Med. 2024 Feb; 56(2): 422–440. Published online 2024 Feb 19. doi: 10.1038/s12276-024-01169-3

PMCID:: PMC10907700

Abstract Article PDF–7.5M

Select item 1084895211.

An extra-clock ultradian brain oscillator sustains circadian timekeeping

Min Tang, Li-Hui Cao, Tian Yang, Si-Xing Ma, Bi-Yang Jing, Na Xiao, Shuang Xu, Kang-Rui Leng, Dong Yang, Meng-Tong Li, Dong-Gen Luo

Sci Adv. 2022 Sep; 8(35): eabo5506. Published online 2022 Sep 2. doi: 10.1126/sciadv.abo5506

PMCID:: PMC10848952

Abstract Article PDF–8.5M

Select item 1082080112.

Ca²⁺ imaging of synaptic compartments using subcellularly targeted GCaMP8f in Drosophila

Jiawen Chen, Kaikai He, Yifu Han, Dion Dickman

STAR Protoc. 2024 Mar 15; 5(1): 102832. Published online 2024 Jan 9. doi: 10.1016/j.xpro.2023.102832

PMCID:: PMC10820801

Abstract Article PDF–4.5M

Select item 1075951613.

Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila

Gabrielle Lim-Kian-Siang, Arianna R. Izawa-Ishiguro, Yong Rao

Mol Brain. 2024; 17: 2. Published online 2024 Jan 2. doi: 10.1186/s13041-023-01073-3

PMCID:: PMC10759516

Abstract Article PDF–2.3M

Select item 1071363814.

Neuronal substrates of egg-laying behaviour at the abdominal ganglion of Drosophila melanogaster

Cristina Oliveira-Ferreira, Miguel Gaspar, Maria Luísa Vasconcelos

Sci Rep. 2023; 13: 21941. Published online 2023 Dec 11. doi: 10.1038/s41598-023-48109-1

PMCID:: PMC10713638

Abstract Article PDF–3.9M

Select item 1069946715.

Cholinergic neurons trigger epithelial Ca²⁺ currents to heal the gut

Afroditi Petsakou, Yifang Liu, Ying Liu, Aram Comjean, Yanhui Hu, Norbert Perrimon

Nature. Author manuscript; available in PMC 2024 May 1.

Published in final edited form as: Nature. 2023 Nov; 623(7985): 122–131. Published online 2023 Sep 18. doi: 10.1038/s41586-023-06627-y

PMCID:: PMC10699467

Abstract Article PDF–7.5M

Select item 1067385716.

Different spectral sensitivities of ON- and OFF-motion pathways enhance the detection of approaching color objects in Drosophila

Kit D. Longden, Edward M. Rogers, Aljoscha Nern, Heather Dionne, Michael B. Reiser

Nat Commun. 2023; 14: 7693. Published online 2023 Nov 24. doi: 10.1038/s41467-023-43566-8

PMCID:: PMC10673857

Abstract Article PDF–4.3M

Select item 1050201317.

Genetic atlas of hygro-and thermosensory cells in the vinegar fly Drosophila melanogaster

Kristina Corthals, Vilma Andersson, Allison Churcher, Johan Reimegård, Anders Enjin

Sci Rep. 2023; 13: 15202. Published online 2023 Sep 14. doi: 10.1038/s41598-023-42506-2

PMCID:: PMC10502013

Abstract Article PDF–5.5M

Select item 1049614918.

Internal sensory neurons regulate stage-specific growth in Drosophila

Yuya Ohhara, Naoki Yamanaka

Development. 2022 Nov 1; 149(21): dev200440. Published online 2022 Oct 28. doi: 10.1242/dev.200440

PMCID:: PMC10496149

Abstract Article

Select item 1043884019.

Growth deregulation and interaction with host hemocytes contribute to tumor progression in a Drosophila brain tumor model

Chrysanthi Voutyraki, Alexandros Choromidis, Anastasia Meligkounaki, Nikolaos Andreas Vlachopoulos, Vasiliki Theodorou, Sofia Grammenoudi, Emmanouil Athanasiadis, Sara Monticelli, Angela Giangrande, Christos Delidakis, Evanthia Zacharioudaki

Proc Natl Acad Sci U S A. 2023 Aug 15; 120(33): e2221601120. Published online 2023 Aug 7. doi: 10.1073/pnas.2221601120

PMCID:: PMC10438840

Abstract Article PDF–4.3M

Select item 1026407420.

Belly roll, a GPI-anchored Ly6 protein, regulates Drosophila melanogaster escape behaviors by modulating the excitability of nociceptive peptidergic interneurons

Kai Li, Yuma Tsukasa, Misato Kurio, Kaho Maeta, Akimitsu Tsumadori, Shumpei Baba, Risa Nishimura, Akira Murakami, Koun Onodera, Takako Morimoto, Tadashi Uemura, Tadao Usui

eLife. 2023; 12: e83856. Published online 2023 Jun 13. doi: 10.7554/eLife.83856